ATP-dependent chromatin remodeling
Graduate School of Biomedical Sciences; Program in Molecular Medicine; Program in Gene Function and Expression
Life Sciences | Medicine and Health Sciences
The study of chromatin and how this dynamic structure modulates events in the eukaryotic nucleus has become an increasingly important topic in biomedical research. A large number of enzymes have been discovered that are responsible for modifying and altering chromatin structure, either globally or specifically at particular gene promoters or regions of the chromosome. This chapter provides an introduction to the structure of chromatin and then describes how special classes of enzymes modulate chromatin structure to allow access to DNA.
DOI of Published Version
Curr Top Dev Biol. 2005;65:115-48. Link to article on publisher's site
Current topics in developmental biology
Smith CL, Peterson CL. (2005). ATP-dependent chromatin remodeling. GSBS Student Publications. https://doi.org/10.1016/S0070-2153(04)65004-6. Retrieved from https://escholarship.umassmed.edu/gsbs_sp/1131