Title
5' avian leukosis virus sequences and osteopetrotic potential
Academic Program
Biochemistry & Molecular Pharmacology
UMMS Affiliation
Graduate School of Biomedical Sciences; Department of Pathology; Department of Molecular Genetics and Microbiology
Publication Date
1992-10-01
Document Type
Article
Disciplines
Life Sciences | Medicine and Health Sciences
Abstract
Recombinants of Rous-associated virus-0 and Br21 have been used to localize 5' viral sequences that affect the osteopetrotic potential of avian leukosis viruses. Rous-associated virus-0 is a benign subgroup E virus of endogenous origin that does not cause osteopetrosis. Br21 is a constructed subgroup E virus with high osteopetrotic potential. 5' sequences that affected osteopetrotic potential resided in an 834-bp region near the 5' LTR. Sequence analysis of this region revealed differences between Br21 and RAV-0 in the mRNA leader and codons for MA.
Source
Virology. 1992 Oct;190(2):866-71.
Journal/Book/Conference Title
Virology
Related Resources
PubMed ID
1325711
Repository Citation
Robinson HL, Foster RG, Blais BP, Reinsch SS, Newstein MC, Shank PR. (1992). 5' avian leukosis virus sequences and osteopetrotic potential. GSBS Student Publications. Retrieved from https://escholarship.umassmed.edu/gsbs_sp/1048