Since the school's inception in 1979, students in the Morningside Graduate School of Biomedical Sciences at UMass Chan Medical School have contributed thousands of research publications to the field of biomedical sciences. This collection makes this body of work accessible to our students, faculty, potential recruits, the citizens of Massachusetts, and the world.

Attention students: Click on Submit Research in the left sidebar to submit your journal articles, posters, and presentations, after reviewing the Submission Guidelines. (Theses and dissertations should be submitted to Dissertations and Theses). You’ll need to log in or create a free account. If your publication appears in PubMed, you can enter the PubMed ID and information from PubMed will be used to populate the submission form. Questions? Contact escholarship@umassmed.edu.

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Publications from 2021

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Rising Black voices in urology - the next generation, Justin K. Achua, Jordan Bilbrew, Keiko Cooley, Amber Herbert, Asia Matthew-Onabanjo, Odinachi Moghalu, Akya Myrie, Nkiruka Odeluga, Jeunice Owens-Walton, Arriana Rieland, Dyvon Walker, and Aboubacar Kaba

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Systematic evaluation of chromosome conformation capture assays, Betul Akgol-Oksuz, Liyan Yang, Sameer Abraham, Sergey V. Venev, Nils Krietenstein, Krishna M. Parsi, Hakan Ozadam, Marlies E. Oomen, Ankita Nand, Hui Mao, Ryan Genga, Rene Maehr, Oliver J. Rando, Leonid A. Mirny, Johan H. Gibcus, and Job Dekker

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The tiny, conserved zinc-finger protein GTSF1 helps PIWI proteins achieve their full catalytic potential [preprint], Amena Arif, Deniz M. Ozata, Cecilia Anderson, Natsuko Izumi, Yukihide Tomari, and Phillip D. Zamore

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Eating-related pathology at the intersection of gender identity and expression, sexual orientation, and weight status: An intersectional Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA) of the Growing Up Today Study cohorts, Ariel L. Beccia, Jonggyu Baek, S. Bryn Austin, William M. Jesdale, and Kate L. Lapane

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Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics, Houda Belaghzal, Tyler M. Borrman, Andrew D. Stephens, Denis L. Lafontaine, Sergey V. Venev, Zhiping Weng, John F. Marko, and Job Dekker

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The Urinary Microbiome of Older Adults Residing in a Nursing Home Varies with Duration of Residence and Shows Increases in Potential Pathogens, Evan Bradley, Brent Schell, Doyle V. Ward, Vanni Bucci, Abigail Zeamer, and John P. Haran

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Targeting prominin2 transcription to overcome ferroptosis resistance in cancer, Caitlin W. Brown, Peter Chhoy, Dimpi Mukhopadhyay, Emmet R. Karner, and Arthur M. Mercurio

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KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection, Nicole Caduff, Donal McHugh, Lisa Rieble, Catherine Forconi, John M. Ong'echa, Peter O. Oluoch, Ana Raykova, Anita Murer, Michelle Boni, Lara Zuppiger, Thomas F. Schulz, David J. Blackbourn, Obinna Chijioke, Ann M. Moormann, and Christian Munz

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Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP [preprint], Christine E. Carbone; Anna B. Loveland; Howard Gamper, Jr.; Ya-Ming Hou; Gabriel Demo; and Andrei A. Korostelev

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Risk factors for monoclonal gammopathy of undetermined significance: a systematic review, Maira Castaneda-Avila, Christine M. Ulbricht, and Mara M. Epstein

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Prevalence and the factors associated with oral anticoagulant use among nursing home residents, Qiaoxi Chen, Kate L. Lapane, Anthony P. Nunes, Jennifer Tjia, Julie Hugunin, and Matthew J. Alcusky

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The role of clinician assistants in addressing perinatal depression, Katherine M. Cooper, Grace A. Masters, Tiffany A. Moore Simas, and Nancy Byatt

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Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants, Nageswara Rao Desaboini, Jacqueto Zephyr, Mina Henes, Elise T. Chan, Ashley N. Matthew, Adam Hedger, Hasahn L. Conway, Mohsan Saeed, Alicia Newton, Christos J. Petropoulos, Wei Huang, Nese Kurt Yilmaz, Celia A. Schiffer, and Akbar Ali

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Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity, William E. Diehl, Mehmet Hakan Guney, Teresa Vanzo, Pyae Phyo Kyawe, Judith M. White, Massimo Pizzato, and Jeremy Luban

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Cardiovascular Health Metrics in Patients Hospitalized with an Acute Coronary Syndrome, Eric Y. Ding, Jordy Mehawej, Hawa Abu, Darleen M. Lessard, Jane S. Saczynski, David D. McManus, Catarina I. Kiefe, and Robert J. Goldberg

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Personal Experiences with Diagnostic Delay Among Axial Spondyloarthritis Patients: A Qualitative Study, Catherine E. Dube, Kate L. Lapane, Katarina A. Ferrucci, Ariel L. Beccia, Sara K. Khan, Esther Yi, Jonathan Kay, Kristine A. Kuhn, Alexis Ogdie, and Shao-Hsien Liu

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An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids, Shawn B. Egri and Kuang Shen

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Genetic and epigenetic features of promoters with ubiquitous chromatin accessibility support ubiquitous transcription of cell-essential genes, Kaili Fan, Jill E. Moore, Xiao-Ou Zhang, and Zhiping Weng

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Physical Activity, Mental Health, and Technology Preferences to Support Cancer Survivors During the COVID-19 Pandemic: Cross-sectional Study, Jamie Faro, Kristin M. Mattocks, Catherine S. Nagawa, Stephenie C. Lemon, Bo Wang, Sarah L. Cutrona, and Rajani S. Sadasivam

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Experiences and perceptions of referrals to a community-based physical activity program for cancer survivors: a qualitative exploration, Jamie M. Faro, Kristin M. Mattocks, Dalton Mourao, Catherine S. Nagawa, Stephenie C. Lemon, Bo Wang, Sarah L. Cutrona, and Rajani S. Sadasivam

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Comparing recruitment strategies for a digital smoking cessation intervention: Technology-assisted peer recruitment, social media, ResearchMatch, and smokefree.gov, Jamie Faro, Catherine S. Nagawa, Elizabeth Aaker Orvek, Bridget M. Smith, Amanda C. Blok, Thomas K. Houston, Ariana Kamberi, Jeroan J. Allison, Sharina D. Person, and Rajani S. Sadasivam

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Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep, Chantal M. Ferguson, Bruno M. D. C. Godinho, Julia F. Alterman, Andrew H. Coles, Matthew R. Hassler, Dimas Echeverria, James W. Gilbert, Emily G. Knox, Jillian Caiazzi, Reka A. Haraszti, Robert M. King, Toloo Taghian, Ajit S. Puri, Richard P. Moser, Matthew J. Gounis, Neil Aronin, Heather L. Gray-Edwards, and Anastasia Khvorova

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Health Care Satisfaction in Relation to Gender Identity: Behavioral Risk Factor Surveillance Survey, 20 States (2014-2018), Katarina A. Ferrucci, Tubanji Walubita, Ariel L. Beccia, Eric Y. Ding, William M. Jesdale, Kate L. Lapane, and Carl G. Streed Jr.

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Widespread occurrence of hybrid internal-terminal exons in human transcriptomes [preprint], Ana Fiszbein, Michael McGurk, Ezequiel Calvo-Roitberg, GyeungYun Kim, Christopher B. Burge, and Athma A. Pai

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Stability of the cytosine methylome during post-testicular sperm maturation in mouse, Carolina Galan, Ryan W. Serra, Fengyun Sun, Vera D. Rinaldi, Colin C. Conine, and Oliver J. Rando

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Simultaneous profiling of multiple chromatin proteins in the same cells [preprint], Sneha Gopalan, Yuqing Wang, Nicholas W. Harper, Manuel Garber, and Thomas G. Fazzio

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BMP Signaling Promotes Neural Crest Identity and Accelerates Melanoma Onset, Alec K. Gramann, William Tyler Frantz, Karen A. Dresser, Camilla Borges Ferreira Gomes, Christine G. Lian, April C. Deng, and Craig J. Ceol

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The epithelial-specific ER stress sensor IRE1β enables host-microbiota crosstalk to affect colon goblet cell development [preprint], Michael J. Grey, Heidi De Luca, Doyle V. Ward, Irini A. M. Kreulen, Sage E. Foley, Jay R. Thiagarajah, Beth A. McCormick, Jerrold R. Turner, and Wayne I. Lencer

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Quantifying the regulatory role of individual transcription factors in Escherichia coli [preprint], Sunil Guharajan, Shivani Chhabra, Vinuselvi Parisutham, and Robert C. Brewster

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SWI/SNF senses carbon starvation with a pH-sensitive low complexity sequence [preprint], J. Ignacio Gutiérrez, Gregory P. Brittingham, Yonca Karadeniz, Kathleen D. Tran, Arnob Dutta, Alex S. Holehouse, Craig L. Peterson, and Liam J. Holt

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Inflammation-type dysbiosis of the oral microbiome associates with the duration of COVID-19 symptoms and long-COVID, John P. Haran, Evan Bradley, Abigail Zeamer, Lindsey Cincotta, Marie-Claire Salive, Protiva Dutta, Shafik Mutaawe, Otuwe Anya, Mario Meza-Segura, Ann M. Moormann, Doyle V. Ward, Beth A. McCormick, and Vanni Bucci

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The high prevalence of Clostridioides difficile among nursing home elders associates with a dysbiotic microbiome, John P. Haran, Doyle V. Ward, Shakti K. Bhattarai, Ethan Loew, Protiva Dutta, Amanda Higgins, Beth A. McCormick, and Vanni Bucci

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The Nursing Home Older Adult Gut Microbiome Composition Shows Time-dependent Dysbiosis and is Influenced by Medication Exposures, Age, Environment, and Frailty, John P. Haran, Abigail Zeamer, Doyle V. Ward, Protiva Dutta, Vanni Bucci, and Beth A. McCormick

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Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB), Benjamin K.I. Helfand, Elke Detroyer, Koen Milisen, Dimitrios Adamis, Eran D. Metzger, Edwin D. Boudreaux, Sharon K. Inouye, and Richard N. Jones

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YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation, Lizhi He, Henry E. Pratt, Mingshi Gao, Fengxiang Wei, Zhiping Weng, and Kevin Struhl

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YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation [preprint], Lizhi He, Henry E. Pratt, Fengxiang Wei, Mingshi Gao, Zhiping Weng, and Kevin Struhl

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Enzymatic enhancing of triplet-triplet annihilation upconversion by breaking oxygen quenching for background-free biological sensing, Ling Huang, Timmy Le, Kai Huang, and Gang Han

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The association between ambient air pollution and birth defects in five major ethnic groups in Liuzhou, China, Xiaoli Huang, Jichang Chen, Dingyuan Zeng, Zhong Lin, Carly Herbert, Lesley Cottrell, Liu Liu, Arlene S. Ash, and Bo Wang

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Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders, Benxia Hu, Hyejung Won, Won Mah, Royce B. Park, Bibi Kassim, Keeley Spiess, Alexey Kozlenkov, Cheynna A. Crowley, Sirisha Pochareddy, Yun Li, Stella Dracheva, Nenad Sestan, Schahram Akbarian, Daniel H. Geschwind, PsychENCODE Consortium, Eugenio Mattei, Michael J. Purcaro, Zhiping Weng, Jill E. Moore, Henry E. Pratt, Jack Huey, and Tyler M. Borrman

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Risk factors associated with suicidal ideation in newly admitted working-age nursing home residents, Julie Hugunin, Yiyang Yuan, Anthony J. Rothschild, Kate L. Lapane, and Christine M. Ulbricht

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Sustained Activation of Endothelial YAP1 Causes Epithelioid Hemangioendothelioma, Roy Jung, Harish Palleti Janardhan, Karen A. Dresser, Jennifer L. Cotton, Lloyd Hutchinson, Junhao Mao, and Chinmay M. Trivedi

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In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate, Su Myung Jung, Will G. Doxsey, Johnny Le, John A. Haley, Lorena Mazuecos, Amelia K. Luciano, Huawei Li, Cholsoon Jang, and David A. Guertin

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D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats, Risako Kato, Edlyn R. Zhang, Olivia G. Mallari, Olivia A. Moody, Kathleen F. Vincent, Eric D. Melonakos, Morgan J. Siegmann, Christa J. Nehs, Timothy T. Houle, Oluwaseun Akeju, and Ken Solt

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Translational Research in Vitiligo, Erica L. Katz and John E. Harris

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PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans, Heesun Kim, Yue-He Ding, Shan Lu, Mei-Qing Zuo, Wendy Tan, Darryl Conte Jr., Meng-Qiu Dong, and Craig C. Mello

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Bacterial processing of glucose modulates C. elegans lifespan and healthspan, Samuel F. Kingsley, Yonghak Seo, Calista Allen, Krishna S. Ghanta, Steven Finkel, and Heidi A. Tissenbaum

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Hi-C 3.0: Improved Protocol for Genome-Wide Chromosome Conformation Capture, Denis L. Lafontaine, Liyan Yang, Job Dekker, and Johan H. Gibcus

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The relationship between restless sleep and symptoms of the knee: data from the Osteoarthritis Initiative, Kate L. Lapane, Divya Shridharmurthy, Matthew S. Harkey, Jeffrey B. Driban, Catherine E. Dube, and Shao-Hsien Liu

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Primary care physician perspectives on screening for axial spondyloarthritis: A qualitative study, Kate L. Lapane, Divya Shridharmurthy, Sara Khan, Daniel Lindstrom, Ariel Beccia, Esther Yi, Jonathan Kay, Catherine E. Dube, and Shao-Hsien Liu

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xCT-Driven Expression of GPX4 Determines Sensitivity of Breast Cancer Cells to Ferroptosis Inducers, Namgyu Lee, Anne E. Carlisle, Austin Peppers, Sung Jin Park, Mihir B. Doshi, Meghan E. Spears, and Dohoon Kim

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Social support and strain and emotional distress among Latinos in the northeastern United States, Shir Lerman Ginzburg, Stephenie C. Lemon, Eric Romo, and Milagros C. Rosal

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A phase transition enhances the catalytic activity of SARM1, an NAD(+) glycohydrolase involved in neurodegeneration, Heather S. Loring, Victoria L. Czech, Janneke D. Icso, Lauren C. O'Connor, Sangram Parelkar, Alexandra B. Byrne, and Paul R. Thompson

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CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection [preprint], Yu-Jung Lu, Palmira Barreira-Silva, Shayla Boyce, Jennifer Powers, Kelly Cavallo, and Samuel M. Behar

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Geographic Variation of Statin Use Among US Nursing Home Residents With Life-limiting Illness, Deborah Mack, Jonggyu Baek, Jennifer Tjia, and Kate L. Lapane

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National Trends in Statin Use among the United States Nursing Home Population (2011-2016), Deborah Mack, Anne L. Hume, Jennifer Tjia, and Kate L. Lapane

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Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae, Kotchaphorn Mangkalaphiban, Feng He, Robin Ganesan, Chan Wu, Richard E. Baker, and Allan Jacobson

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Impact of the COVID-19 pandemic on mental health, access to care, and health disparities in the perinatal period, Grace A. Masters, Eugenia Asipenko, Aaron Bergman, Aaron L. Bergman, Sharina D. Person, Linda Brenckle, Tiffany Moore Simas, Jean Y. Ko, Cheryl L. Robbins, and Nancy Byatt

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Development of the Practice Readiness to Evaluate and address Perinatal Depression (PREPD) assessment, Grace A. Masters, Linda Brenckle, Padma Sankaran, Tiffany Moore Simas, Sharina D. Person, Jeroan J. Allison, Douglas Ziedonis, Jean Ko, Cheryl Robbins, and Nancy Byatt

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Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond, Ashley N. Matthew, Florian Leidner, Gordon J. Lockbaum, Mina Henes, Jacqueto Zephyr, Shurong Hou, Nageswara Rao Desaboini, Jennifer Timm, Linah N. Rusere, Debra A. Ragland, Janet L. Paulsen, Kristina L. Prachanronarong, Djade I. Soumana, Ellen A. Nalivaika, Nese Kurt Yilmaz, Akbar Ali, and Celia A. Schiffer

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Complex Patients Have More Emergency Visits: Don't Punish the Systems That Serve Them, Eric O. Mick, Matthew J. Alcusky, Nien-Chen Li, Frances E. Eanet, Jeroan J. Allison, Catarina I. Kiefe, and Arlene S. Ash

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Quantifying and Mitigating Motor Phenotypes Induced by Antisense Oligonucleotides in the Central Nervous System [preprint], Michael P. Moazami, Julia M. Rembetsy-Brown, Feng Wang, Pranathi Meda Krishnamurthy, Alexandra Weiss, Miklos G. Marosfoi, Robert M. King, Mona Motwani, Heather L. Gray-Edwards, Katherine A. Fitzgerald, Robert H. Brown Jr., and Jonathan K. Watts

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Association of killer cell immunoglobulin-like receptors with endemic Burkitt lymphoma in Kenyan children, Beatrice M. Muriuki, Catherine Forconi, Peter O. Oluoch, Jeffrey A. Bailey, Anita Ghansah, Ann M. Moormann, and John M. Ong'echa

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Written Advice Given by African American Smokers to Their Peers: Qualitative Study of Motivational Messages, Catherine S. Nagawa, Jamie M. Faro, Anitha J. Menon, Mayuko Ito Fukunaga, Jessica H. Williams, Dalton Mourao, Oluwabunmi M. Emidio, Maryann Davis, Lori Pbert, Sarah L. Cutrona, Thomas K. Houston, and Rajani S. Sadasivam

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Herbal or Dietary Supplement Use and Hypertensive Medications: Does the Combination Relate to Medication Adherence and Blood Pressure Control, Catherine S. Nagawa, Jessica A. Palakshappa, Rajani S. Sadasivam, and Thomas K. Houston

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Emerging Immunotherapies in the Treatment of Brain Metastases, Edwin Nieblas-Bedolla, Naema Nayyar, Mohini Singh, Ryan J. Sullivan, and Priscilla K. Brastianos

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Hinfp is a guardian of the somatic genome by repressing transposable elements, Niraj K. Nirala, Qi Li, Prachi N. Ghule, Hsi-Ju Chen, Rui Li, Lihua Julie Zhu, Ruijia Wang, Nicholas P. Rice, Junhao Mao, Janet L. Stein, Gary S. Stein, Andre J. van Wijnen, and Y. Tony Ip

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Multiple imputation to quantify misclassification in observational studies of the cognitively impaired: an application for pain assessment in nursing home residents, Anthony P. Nunes, Danni Zhao, William M. Jesdale, and Kate L. Lapane

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Allele-specific knockdown of mutant HTT protein via editing at coding region SNP heterozygosities, Sarah Oikemus, Edith L. Pfister, Ellen Sapp, Kathryn O. Chase, Lori A. Kennington, Edward Hudgens, Rachael Miller, Lihua Julie Zhu, Akanksh Chaudhary, Eric O. Mick, Miguel Sena-Esteves, Scot A. Wolfe, Marian DiFiglia, Neil Aronin, and Michael H. Brodsky

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The testis-specific transcription factor TCFL5 responds to A-MYB to elaborate the male meiotic program in placental mammals [preprint], Deniz M. Ozata, Tianxiong Yu, Katharine Cecchini, Haiwei Mou, Amena Arif, Cansu Colpan, Adriano Biasini, Ildar Gaitendinov, Dirk G. de Rooij, Zhiping Weng, and Phillip D. Zamore

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Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice, Pengpeng Liu, Shun-Qing Liang, Chunwei Zheng, Esther Mintzer, Yan G. Zhao, Karthikeyan Ponnienselvan, Aamir Mir, Erik J. Sontheimer, Guangping Gao, Terence R. Flotte, Scot A. Wolfe, and Wen Xue

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Factorbook: an Updated Catalog of Transcription Factor Motifs and Candidate Regulatory Motif Sites [preprint], Henry E. Pratt, Gregory Andrews, Nishigandha Phalke, Michael J. Purcaro, Arjan van der Velde, Jill E. Moore, and Zhiping Weng

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Type I IFN-Driven Immune Cell Dysregulation in Rat Autoimmune Diabetes, Natasha Qaisar, Adediwura Arowosegbe, Alan G. Derr, Alper Kucukural, Basanthi Satish, Riccardo Racicot, Zhiru Guo, Melanie I. Trombly, and Jennifer P. Wang

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A conserved neuropeptide system links head and body motor circuits to enable adaptive behavior, Shankar Ramachandran, Navonil Banerjee, Raja Bhattacharya, Michele L. Lemons, Jeremy Florman, Christopher M. Lambert, Denis Touroutine, Kellianne Alexander, Liliane Schoofs, Mark J. Alkema, Isabel Beets, and Michael M. Francis

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Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia, Monica Reis, Gareth R. Willis, Angeles Fernandez-Gonzalez, Vincent Yeung, Elizabeth Taglauer, Margaret Magaletta, Teagan J. Parsons, Alan G. Derr, Xianlan Liu, Rene Maehr, Stella Kourembanas, and S. Alex Mitsialis

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FLICK: an optimized plate reader-based assay to infer cell death kinetics, Ryan Richards, Megan E. Honeywell, and Michael J. Lee

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Multi-tissue integrative analysis of personal epigenomes [preprint], Joel Rozowsky, Jill E. Moore, Henry E. Pratt, Zhiping Weng, and Mark Gerstein

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Analysis of Emerging Variants in Structured Regions of the SARS-CoV-2 Genome, Sean P. Ryder, Brittany R. Morgan, Peren Coskun, Katianna Antkowiak, and Francesca Massi

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Disease Burden and Health-Related Quality of Life Among Women and Men with Spondyloarthritis: An Exploratory Analysis of a Population-Based Sample, Divya Shridharmurthy, Danni Zhao, Kate L. Lapane, Jonggyu Baek, Jonathan Kay, and Shao-Hsien Liu

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Lessons from a local effort to screen for SARS-CoV-2, Noah J. Silverstein and Jeremy Luban

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Innate lymphoid cells and disease tolerance in SARS-CoV-2 infection [preprint], Noah J. Silverstein, Yetao Wang, Zachary Manickas-Hill, Claudia C. Carbone, Ann Dauphin, MGH COVID-19 Collection & Processing Team, Jonathan Z. Li, Bruce D. Walker, Xu G. Yu, and Jeremy Luban

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c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease [preprint], Abigail O. Smith, Julie A. Jonassen, Kenley Preval, Roger J. Davis, and Gregory J. Pazour

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Cell-type specific circadian bioluminescence rhythms recorded from Dbp reporter mice reveal circadian oscillator misalignment [preprint], Ciearra B. Smith, Vincent van der Vinne, Eleanor McCartney, Adam C. Stowie, Tanya L. Leise, Blanca Martin-Burgos, Penny C. C. Molyneux, Lauren A. Garbutt, Michael H. Brodsky, Alec J. Davidson, Mary E. Harrington, Robert Dallmann, and David R. Weaver

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Sirtuin 3 Downregulation in Mycobacterium tuberculosis-Infected Macrophages Reprograms Mitochondrial Metabolism and Promotes Cell Death, Lorissa J. Smulan, Nuria M. Martinez, Michael C. Kiritsy, Chido L. Kativhu, Kelly Cavallo, Christopher M. Sassetti, Amit Singhal, Heinz G. Remold, and Hardy Kornfeld

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Single-cell RNA-seq reveals transcriptomic heterogeneity mediated by host-pathogen dynamics in lymphoblastoid cell lines, Elliott D. SoRelle, Joanne Dai, Emmanuela N. Bonglack, Emma M. Heckenberg, Jeffrey Y. Zhou, Stephanie N. Giamberardino, Jeffrey A. Bailey, Simon G. Gregory, Cliburn Chan, and Micah A. Luftig

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Yeast Particle Encapsulation of Scaffolded Terpene Compounds for Controlled Terpene Release, Ernesto R. Soto, Florentina Rus, Hanchen Li, Carli Garceau, Jeffrey Chicca, Elfawal A. Mostafa, David Gazzola, Martin K. Nielsen, Joseph F. Urban Jr., Raffi V. Aroian, and Gary R. Ostroff

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Protection of mice against experimental cryptococcosis by synthesized peptides delivered in glucan particles [preprint], Charles A. Specht, E. Jane Homan, Chrono K. Lee, Zhongming Mou, Christina L. Gomez, Maureen M. Hester, Ambily Abraham, Florentina Rus, Gary R. Ostroff, and Stuart M. Levitz

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Nox4 mediates skeletal muscle metabolic responses to exercise, Kalyn S. Specht, Shashi Kant, Heather Learnard, Maura Campbell, Amada D. Caliz, Yongmei Pei, Michaella M. Reif, John F. Keaney Jr., and Siobhan M. Craige

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Methodological Challenges for Epidemiologic Studies of Deprescribing at the End of Life, Jennifer Tjia, Jennifer L. Lund, Deborah Mack, Attah Mbrah, Yiyang Yuan, Qiaoxi Chen, Seun Osundolire, and Cara L. McDermott

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Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide, Helene Tran, Michael P. Moazami, Huiya Yang, Diane Mckenna-Yasek, Catherine Douthwright, Courtney Pinto, Jake P. Metterville, Minwook Shin, Nitasha Sanil, Craig Dooley, Ajit S. Puri, Alexandra Weiss, Nicholas Wightman, Heather L. Gray-Edwards, Miklos G. Marosfoi, Robert M. King, Jonathan K. Watts, and Robert H. Brown Jr.

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Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction, Motokazu Uchigashima, Amy Cheung, and Kensuke Futai

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Annotation of chromatin states in 66 complete mouse epigenomes during development, Arjan van der Velde, Kaili Fan, Junko Tsuji, Jill E. Moore, Michael J. Purcaro, Henry E. Pratt, and Zhiping Weng

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Inactivation of the Hippo Tumor Suppressor Pathway Promotes Melanoma [preprint], Marc A. Vittoria, Nathan Kingston, Eric Xia, Rui Hong, Lee Huang, Shayna McDonald, Andrew Tilston- Lunel, Revati A. Darp, Joshua Campbell, Deborah Lang, Xiaowei Xu, Craig J. Ceol, Xaralabos Varelas, and Neil J. Ganem

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WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization, Melissa D. Walker, Gabrielle E. Giese, Amy D. Holdorf, Sushila Bhattacharya, Cedric Diot, Aurian Garcia-Gonzalez, Brent Horowitz, Yong-Uk Lee, Thomas Leland, Xuhang Li, Zeynep Mirza, Huimin Na, Shivani Nanda, Olga Ponomarova, Hefei Zhang, Jingyan Zhang, L. Safak Yilmaz, and Albertha J. M. Walhout

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Development and Validation of an Automated Algorithm to Detect Atrial Fibrillation Within Stored Intensive Care Unit Continuous Electrocardiographic Data: Observational Study, Allan J. Walkey, Syed K. Bashar, Md Billal. Hossain, Eric Y. Ding, Daniella Albuquerque, Michael Winter, Ki H. Chon, and David D. McManus

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Aging and COVID-19 in Minority Populations: a Perfect Storm, Tubanji Walubita, Ariel Beccia, Esther Boama-Nyarko, Melissa Goulding, Carly Herbert, Jessica Kloppenburg, Guadalupe Mabry, Grace A. Masters, Asli McCullers, and Sarah N. Forrester

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Deficient spermiogenesis in mice lacking Rlim, Feng Wang, Maria Gracia Gervasi, Ana Boskovic, Fengyun Sun, Vera D. Rinaldi, Jun Yu, Mary C. Wallingford, Darya A. Tourzani, Jesse Mager, Lihua Julie Zhu, Oliver J. Rando, Pablo E. Visconti, Lara Strittmatter, and Ingolf Bach

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Role of epigenetics in unicellular to multicellular transition in Dictyostelium, Simon Yuan Wang, Elizabeth Ann Pollina, I-Hao Wang, Lindsay Kristina Pino, Henry L. Bushnell, Ken Takashima, Colette Fritsche, George Sabin, Benjamin Aaron. Garcia, Paul L. Greer, and Eric Lieberman Greer

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Clarification of human blood ILC subtype interrelatedness and discovery of amphiregulin production by human NK cells shed light on HIV-1 pathogenesis [preprint], Yetao Wang, Lawrence M. Lifshitz, Noah J. Silverstein, Esther Mintzer, Kevin Luk, Pamela St. Louis, Michael A. Brehm, Scot A. Wolfe, Steven G. Deeks, and Jeremy Luban

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NHR-49/PPAR-alpha and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase, Khursheed A. Wani, Debanjan Goswamy, Stefan Taubert, Ramesh Ratnappan, Arjumand Ghazi, and Javier E. Irazoqui

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The Intestinal and Oral Microbiomes Are Robust Predictors of COVID-19 Severity the Main Predictor of COVID-19-related Fatality [preprint], Doyle V. Ward, Shakti Bhattarai, Mayra Rojas-Correa, Ayan Purkayastha, Devon Holler, Ming Da Qu, William G. Mitchell, Jason D. Yang, Samuel Fountain, Abigail Zeamer, Catherine Forconi, Gavin Fujimori, Boaz Odwar, Caitlin Cawley, Beth A. McCormick, Ann M. Moormann, Mireya Wessolossky, Vanni Bucci, and Ana Maldonado-Contreras