GSBS Dissertations and Theses

 

Since the school's inception in 1979, students in the Graduate School of Biomedical Sciences (GSBS) have contributed hundreds of doctoral dissertations and masters theses to the field of biomedical sciences. The GSBS Dissertations and Theses collection makes this body of work accessible to our students, faculty, potential recruits, and the citizens of Massachusetts.

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Publications from 2011

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Investigation of the C-Terminal Helix of HIV-1 Matrix: A Region Essential for Multiple Functions in the Viral Life Cycle: A Dissertation, Laura A. Brandano

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The Role of PC4 in Oxidative Stress: A Dissertation, Lijian Yu

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Quantitative Analysis of Novel Chemical and shRNA Based Methods to Increase Survival of Motor Neuron Protein Levels, Matthew C. Evans

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Regulation of Humoral Immunity by Pim Kinases: A Dissertation, Kristen N. Willems

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Investigating Age-Dependent Arthropathy in a Circadian Mutant Mouse Model: A Dissertation, Elizabeth A. Yu

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Mechanisms of Substrate Recognition by HCV NS3/4A Protease Provide Insights Into Drug Resistance: A Dissertation, Keith P. Romano

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Inflammation Alters Histone Methylation in the Central Nervous System: Implications for Neuropsychiatric Disease: A Dissertation, Caroline M. Connor

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The Importance of the Centrosomal Localization Sequence of Cyclin E for Promoting Centrosome Duplication: A Dissertation, Joshua J. Nordberg

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A Global Analysis of the Adaptations Required for Sterol Catabolism in Mycobacterium Tuberculosis: A Dissertation, Jennifer E. Griffin

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Conformational Lability in MHC II Proteins: A Dissertation, Corrie A. Painter

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Blocking the Notch Pathway with Gamma-Secretase Inhibitors Enhances Temozolomide Treatment of Gliomas through Therapy-Induced Senescence: A Dissertation, Candace A. Gilbert

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A Tale of Two SNPS: Polymorphism Analysis of Toll-like Receptor (TLR) Adapter Proteins: A Dissertation, Kamalpreet Nagpal

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Identification of a Command Neuron Directing the Expression of Feeding Behavior in Drosophila melanogaster: A Dissertation, Thomas F. Flood

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Critical and Independent Roles of the P/CAF Acetyltransferase in ARF-p53 Signaling: A Dissertation, Ian M. Love

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Roles of Secreted Virulence Factors in Pathogenicity of Haemophilus Influenzae: A Dissertation, Charles V. Rosadini

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Critical Molecular Pathways in Cancer Stem Cells of Chronic Myeloid Leukemia: A Dissertation, Yaoyu Chen

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Insulin Receptor Substrate-2 (IRS-2): A Novel Hypoxia-Responsive Gene in Breast Cancer: A Dissertation, Katerina Mardilovich

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The Role of miR-21 and miR-31 in Cellular Responses Mediated by TGF-β: A Dissertation, Charisa L. Cottonham

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Hsp90-Mediated Maturation of Kinases and Nuclear Steroid Hormone Receptors: A Dissertation, Natalie W. Pursell

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Factors Associated with Ordering and Completion of Laboratory Monitoring Tests for High-Risk Medications in the Ambulatory Setting: A Dissertation, Shira H. Fischer

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Molecular Mechanisms of piRNA Biogenesis and Function in Drosophila: A Dissertation, Chengjian Li

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The Effect of Glycemic Index and Glycemic Load on Glucose Control, Lipid Profiles and Anthropometrics Among Low-Income Latinos With Type 2 Diabetes: A Dissertation, Lauren A. Gellar

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Dissecting Signaling Pathways that Regulate Axonal Guidance Effects of Sonic Hedgehog: A Dissertation, Daorong Guo

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The Function of Innate γδ T Cell Subsets is Molecularly Programmed in the Thymus in Three Stages: A Dissertation, Kavitha Narayan

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Cooperating Events in Core Binding Factor Leukemia Development: A Dissertation, Dmitri Madera

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Molecular and Functional Properties of Transmitted HIV-1 Envelope Variants: A Dissertation, Michael G. Kishko

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Role of the Yeast Ste20 Protein Kinase Ortholog Map4k4 in Adipose Tissue Function: A Dissertation, Kalyani V. P. Guntur

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Neuronal Nicotinic Acetylcholine Receptors: Molecular Targets for Alcoholism and Ethanol Reward: A Dissertation, Linzy M. Hendrickson

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Improved Methods of Sepsis Case Identification and the Effects of Treatment with Low Dose Steroids: A Dissertation, Huifang Zhao

Publications from 2010

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Clinical Course of Bipolar Disorder During the Menopausal Transition: Comparison with Reproductive Age and Post Menopausal Women: A Master's Thesis, Wendy K. Marsh

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Host Cell Attachment by Lyme Disease and Relapsing Fever Spirochetes: A Dissertation, Vivian M. Benoit

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Immunity, Pathogenesis, and Prevention of Poxvirus Infections: A Dissertation, Mina O. Seedhom

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The C Terminus of Activation Induced Cytidine Deaminase (AID) Recruits Proteins Important for Class Switch Recombination to the IG Locus: A Dissertation, Sanjay Ranjit

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Axon Death Prevented: Wlds and Other Neuroprotective Molecules: A Dissertation, Michelle A. Avery

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CD8+ T Cell Serotype-Cross-Reactivity is a Predominant Feature of Dengue Virus Infections in Humans: A Dissertation, Heather L. Friberg-Robertson

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MRI Contrast Agent Studies of Compartmental Differentiation, Dose-Dependence, and Tumor Characterization in the Brain: A Dissertation, Mohammed S. Shazeeb

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A Mindfulness-Based Intervention for Treatment of Anxiety in ICD Patients: Feasibility and Baseline Findings: A Dissertation, Elena Salmoirago Blotcher

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Converging Pathways in the Regulation of Longevity and Metabolism in Caenorhabditis Elegans: A Dissertation, Sri Devi Narasimhan

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Drosophila piRNA Function in Genome Maintenance, Telomere Protection and Genome Evolution: A Dissertation, Jaspreet S. Khurana

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Regulation of Cellular and HIV-1 Gene Expression by Positive Transcription Elongation Factor B: A Dissertation, Siobhan O'Brien

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Beyond Toll-Like Receptor 9: Interactions Between Plasmacytoid Dendritic Cells and Aspergillus Fumigatus: A Dissertation, Zaida G. Ramirez-Ortiz

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Acute Modulation of Endothelial Cell Glucose Transport: A Dissertation, Anthony J. Cura

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Generating Nucleosomal Asymmetry in Saccharomyces cerevisiae: A Masters Thesis, Yuanyuan Chen

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Energy Metabolism and the Induction of the Unfolded Protein Response: A Dissertation, Alison M. Burkart

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A Glia-Mediated Feedback Mechanism for the Termination of Drosophila Visual Response: A Dissertation, Peiyi Guo

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Mitochondrial Dysfunction and AKT Isoform-Specific Regulation in 3T3-L1 Adipocytes: A Dissertation, Xiarong Shi

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Regulation of Early T Cell Activation by TNF Superfamily Members TNF and FASL: A Dissertation, Bhavana Priyadharshini

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Elucidating the Transcriptional Network Underlying Expression of a Neuronal Nicotinic Receptor Gene: A Dissertation, Michael D. Scofield

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Magnetic Resonance Imaging of Neural and Pulmonary Vascular Function: A Dissertation, Ronn P. Walvick

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Structural and Functional Studies of Proteins Involved in Antigen Processing: A Dissertation, Tina T. Nguyen

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Mechanical Flow Restoration in Acute Ischemic Stroke: A Model System of Cerebrovascular Occlusion: A Dissertation, Juyu Chueh

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Dissecting the Role of Innate Pattern Recognition Receptors and Interferon Regulatory Factor-5 in the Immune Response to Human Metapneumovirus and other Pathogens: A Dissertation, Zhaozhao Jiang

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Elucidation of the Multi-Faceted Roles of the SIN (Septation Initiation Network); Understanding How the SIN Promotes Cytokinesis and Inhibits Interphase Growth in the Fission Yeast Schizosaccharomyces pombe: A Dissertation, Samriddha Ray

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Maternally Derived Anti-Dengue Antibodies and Risk of DHF in Infants: A Case-Control Study, Steven Hatch

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C. Elegans Metabolic Gene Regulatory Networks: A Dissertation, H. Efsun Arda

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Role of CPEB in Senescence and Inflammation: A Dissertation, Maria Ivshina

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Novel Complement Blocking Antibodies Against Serogroup B N. meningitidis: A Dissertation, Tathagat Dutta Ray

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Post-Transcriptional Control of Human Cellular Senescence: A Dissertation, David M. Burns

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Role of the cJun NH2-Terminal Kinase (JNK) in Cancer: A Dissertation, Cristina Arrigo Cellurale

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Endocytosis, Phagocytosis, and Innate Immune Responses: A Dissertation, Christine A. St. Pierre

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Clinically Relevant Doses of Chemotherapy Drugs Selectively and Reversibly Block Glioblastoma Neurosphere Proliferation in vitro: A Dissertation, Alicia M. Mihaliak

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A Novel Motif in HIV-1 Nef that Regulates MIP-1β Chemokine Release in Macrophages: A Dissertation, Lue Dai

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Pathogenesis of the Helicobacter Induced Mucosal Disease: A Dissertation, Calin Stoicov

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Sequence Determinants of the Folding Free-Energy Landscape of beta alpha-Repeat Proteins: A Dissertation, Sagar V. Kathuria

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The Coupling Between Folding, Zinc Binding, and Disulfide Bond Status of Human Cu, Zn Superoxide Dismutase: A Dissertation, Can Kayatekin

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T Cells Aid in Limiting Pathogen Burden and in Enhancing B1 and B2 Cell Antibody Responses to Membrane Glycolipid and the Surface Lipoprotein Decorin-Binding Protein A during Borrelia burgdorferi Infection: A Dissertation, Robyn Lynn Marty-Roix

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Roles of Cellular RNA-Dependent RNA Polymerases in Endogenous Small RNA Pathways in Caenorhabditis elegans: A Dissertation, Jessica J. Vasale

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Molecular Mechanisms of Neurite Complexity in the Drosophila Brain: A Dissertation, Lei Shi

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Co– and Post–Translational N–Linked Glycosylation of Cardiac Potassium Channel Subunits: A Dissertation, Tuba Bas

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Regulation of WRN Function by Acetylation and SIRT1-Mediated Deacetylation in Response to DNA Damage: A Dissertation, Kai Li

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RNA Recognition by the Caenorhabditis elegans Embryonic Determinants MEX-5 and MEX-3: A Dissertation, John M. Pagano Jr.

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Role and Regulation of Fat Specific Protein (FSP27) in Lipolysis in 3T3-L1 Adipocytes: A Dissertation, Srijana Ranjit

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A Tale of Two ARFs: Tumor Suppressor and Anti-viral Functions of p14ARF: A Dissertation, Michael W. Straza

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Exploring Molecular Mechanisms of Drug Resistance in HIV-1 Protease through Biochemical and Biophysical Studies: A Dissertation, Rajintha M. Bandaranayake

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Novel Therapeutic Targets for Ph+ Chromosome Leukemia and Its Leukemia Stem Cells: A Dissertation, Cong Peng

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Description, Classification, and Prediction of Dengue Illnesses in a Thai Pediatric Cohort: A Dissertation, James A. Potts

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Role of Internal Calcium Stores in Exocytosis and Neurotransmission: A Dissertation, Jason J. Lefkowitz

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Factors Associated with Subjective Improvement Following Midurethral Sling Procedures for Stress Urinary Incontinence: A Masters Thesis, Emily Elise Weber Lebrun

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Glycosylation, Assembly and Trafficking of Cardiac Potassium Channel Complexes: A Dissertation, Kshama D. Chandrasekhar

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Age and Sex Differences in Duration of Pre-Hospital Delay, Hospital Treatment Practices, and Short-Term Outcomes in Patients Hospitalized with an Acute Coronary Syndrome/Acute Myocardial Infarction: A Dissertation, Hoa L. Nguyen

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Role of the Monocyte/Macrophage Cell Lineage in Obesity-Related Insulin Resistance, Olga T. Hardy

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The Role of Rip2 Protein in the Nod Mediated Innate Immune Response: A Dissertation, Yibin Yang

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Regulation of Immune Pathogenesis by Antigen-Specific CD8 T Cells Following Sequential Heterologous Infections: A Dissertation, Alex T. Chen

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Antibody Responses Elicited by DNA Prime-Protein Boost HIV Vaccines: A Dissertation, Michael Vaine

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Identification and Characterization of SNAPIN as a Novel Antagonist of HIV-1 Egress: A Dissertation, Patrick Younan

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A View of the IMD Pathway from the RHIM, Kamna Aggarwal

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Transcriptional Regulation of VEGFA by Unfolded Protein Response Signaling Pathway, Rajarshi Ghosh

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Endogenous Small RNAs in the Drosophila Soma: A Dissertation, Megha Ghildiyal

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An Integral Role of ARRDC3 in Stem Cell Migration and Breast Cancer Progression: A Dissertation, Kyle M. Draheim

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Behavioral Health Disorders and the Quality of Diabetes Care: A Dissertation, Yat (Gary) Hung Leung

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The Role of Dynamic Cdk1 Phosphorylation in Chromosome Segregation in Schizosaccharomyces pombe: A Dissertation, Sung Hugh Choi

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Cross-Talk Between Factors Involved in mRNA Translation and Decay: A Dissertation, Shubhendu Ghosh

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Development and Evaluation of Disease Activity Measures in Rheumatoid Arthritis Using Multi-Level Mixed Modeling and Other Statistical Methodologies: A Dissertation, Mary Jane Bentley

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Maintenance of Visual Sensitivity in the Drosophila Eye: A Dissertation, Lina Ni

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Defining the Roles of p300/CBP (CREB Binding Protein) and S5a in p53 Polyubiquitination, Degradation and DNA Damage Responses: A Dissertation, Dingding Shi

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Development of a Multi-Site Phase II Clinical Trial of Valproic Acid for Retinitis Pigmentosa, Christine Moulton Clemson

Publications from 2009

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Evasion of LPS-TLR4 Signaling as a Virulence Determinate for Yersinia pestis, Sara Montminy Paquette

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Identification of the Function of the Vpx Protein of Primate Lentiviruses: A Dissertation, Xiaonan Zhu

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The Role of Macropinocytosis in Sonic Hedgehog-Induced Axon Growth and Guidance: A Dissertation, Adrianne L. Kolpak

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Pathophysiology of Respiratory Failure Following Acute Organophosphate Poisoning : A Dissertation, Romolo Joseph Gaspari

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Regulation of the Cdc14-like Phosphatase CLP1 in Schizosaccharomyces pombe and Identification of SID2 Kinase Substrates: A Dissertation, Chun-Ti Chen

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Elucidation of the Role of the Exocyst Subunit Sec6p in Exocytosis: A Dissertation, Daniel Niron Brewer

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Endoderm Patterning in Zebrafish: Pancreas Development: A Dissertation, Kristen M. Alexa

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Co-evolution of HIV-1 Protease and its Substrates: A Dissertation, Madhavi Kolli

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Caspase Mediated Cleavage, IAP Binding, Ubiquitination and Kinase Activation : Defining the Molecular Mechanisms Required for Drosophila NF-кB Signaling: A Dissertation, Nicholas Paul Paquette

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Energetic and Dynamic Analysis of Inhibitor Binding to Drug-Resistant HIV-1 Proteases: A Dissertation, Yufeng Cai

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Sensitization of CD8 T Cells During Acute Viral Infections Impacts Bystander and Latecomer CD8 T Cell Responses : A Dissertation, Heather D. Marshall

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Neural Circuit Analyses of the Olfactory System in Drosophila: Input to Output: A Dissertation, Shamik DasGupta

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A Multiparameter Network Reveals Extensive Divergence Between C. elegans bHLH Transcription Factors: A Dissertation, Christian A. Grove

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Hypoxia Inducible Factors in Alcoholic Liver Disease: A Dissertation, Bharath D. Nath

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Mechanisms of NOTCH1 Mediated Leukemogenesis: A Dissertation, Kathleen J. Cullion

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Injection Treatment for Lower Back Pain in Older Adults with Lumbar Spinal Stenosis: A Dissertation, Virginia G. Briggs

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Regulation of BACH1/FANCJ Function in DNA Damage Repair: A Dissertation, Jenny X. Xie

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Cytoskeletal Regulation and Morphogen Signaling During Synaptic Outgrowth at the Drosophila Larval Neuromuscular Junction : A Dissertation, Preethi Ramachandran

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Characterization of the Nef-TCR Zeta Interaction and Its Role in Modulation of Src Family Kinase Activity: A Dissertation, Walter Minsub Kim

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Regulation of DNA Replication Origins in Fission Yeast: A Dissertation, Naveen Kommajosyula

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Respiratory Syncytial Virus (RSV) Induces Innate Immunity through Toll-Like Receptors and Acquired Immunity via the RSV G Protein: A Dissertation, Matthew R. Murawski

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Regulation of Cancer Cell Survival Mediated by Endogenous Tumor Suppression: A Dissertation, Minakshi Guha

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Long-Range Side Chain-Main Chain Hydrogen Bonds: A Molecular Signature of the TIM Barrel Architecture: A Dissertation, Xiaoyan Yang

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IAP Regulation of Tumor Metastasis: A Dissertation, Swarna Mehrotra

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Functional Elements of EspFu, an Enterohemorrhagic E. coli Effector that Stimulates Actin Assembly: A Dissertation, Brian M. Skehan

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Defining the Role of CtBP2 in p53-Independent Tumor Suppressor Function of ARF: A Dissertation, Ramesh C. Kovi

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Modeling Co-Occurring Depression and Anxiety in Patients with an Acute Coronary Syndrome: A Dissertation, Mayra Tisminetzky

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Study of the Function and Dynamics of Myosin II and Actin in Cytokinesis: A Dissertation, Mian Zhou

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Checkpoint Regulation of Replication Forks in Response to DNA Damage: A Dissertation, Nicholas Adrian Willis

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Systems Level Processing of Memory in the Fly Brain: A Dissertation, Michael Jonathan Krashes

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Functional Analysis of MicroRNA-10b in Breast Carcinoma: A Dissertation, Charlotte M. Harwood Moriarty

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The Circadian Clock in Monarch Butterfly: A Tale of Two CRYs: A Dissertation, Quan Yuan

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Nuclear Dynamics of a Broken Chromosome: A Dissertation, Pranav O. Oza

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Functional Analysis of Yeast Pheromone Receptors in ER Exit, Ligand-Induced Endocytosis and Oligomerization: A Dissertation, Chien-I Chang

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Chromatin Remodeling in Transgenic Mouse Brain: Implications for the Neurobiology of Depression: A Dissertation, Yan Jiang

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Prediction, Prevention and Treatment of Virally Induced Type 1 Diabetes: A Dissertation, Annie J. Kruger

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Defining the Importance of Fatty Acid Metabolism in Maintaining Adipocyte Function: A Dissertation, Jennifer L. Christianson

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Worming to Complete the Insulin/IGF-1 Signaling Cascade: A Dissertation, Srivatsan Padmanabhan

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Analysis of Long-Range Chromosomal Interactions in Saccharomyces cerevisiae: A Dissertation, Adriana Miele

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Delineating the C. elegans MicroRNA Regulatory Network: A Dissertation, Natalia Julia Martinez

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An Omega-Based Bacterial One-Hybrid System for the Determination of Transcription Factor Specificity, Marcus Blaine Noyes

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Recombinational Repair of a Chromosomal DNA Double Strand Break: A Dissertation, Manisha Sinha

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Differentially Expressed MicroRNAs Act As Inhibitors of BDNF in Prefrontal Cortex - Implications for Schizophrenia: A Dissertation, Nikolaos Mellios

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Role of WFS1 in Regulating Endoplasmic Reticulum Stress Signaling: A Dissertation, Sonya G. Fonseca

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Functional Interaction of BPV-1 E2 with the Papillomavirus Genome: A Dissertation, Suzanne Marie Melanson

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Role of Supervillin, a Membrane Raft Protein, in Cytoskeletal Organization and Invadopodia Function, Jessica Lynn Crowley

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Multifaceted Regulation of Peripheral T Cell Tolerance and Autoimmunity by FOXP3+ T Regulatory Cells: A Dissertation, Nitya Jain

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The Role of the MRN Complex in the S-Phase DNA Damage Checkpoint: A Dissertation, Mary Elizabeth Porter-Goff

Publications from 2008

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Bone Health and Coronary Heart Disease in Postmenopausal Women with Breast Cancer Treated with Tamoxifen: A Dissertation, Hongliu Ding

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Ethanol Sensitivity and Tolerance of Rat Neuronal BK Channels: A Dissertation, Patricia M. Wynne

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Chromatin Remodeling and Transcriptional Memory: A Dissertation, Sharmistha Kundu

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Adipocyte Insulin-Mediated Glucose Transport: The Role of Myosin 1c, and a Method for in vivo Investigation: A Dissertation, G. Nana Hagan

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VPS45p as a Model System for Elucidation of SEC1/MUNC18 Protein Function: A Dissertation, Melonnie Lynn Marie Furgason

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Effect of KCNE1 and KCNE3 Accessory Subunits on KCNQ1 Potassium Channel Function: A Dissertation, Jessica Marie Rocheleau

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piRNA Function and Biogenesis in the Drosophila Female Germline: A Dissertation, Carla Andrea Klattenhoff

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Regulation of Reactive Nitrogen Species (RNS) Metabolism and Resistance Mechanisms in Haemophilus influenzae: A Dissertation, Jane Colleen Harrington

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Role of TNF in Heterologous Immunity between Lymphocytic Choriomeningitis Virus and Vaccinia Virus: A Dissertation, Siwei Nie

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The Role of Janus-Kinase-3 in CD4+ T Cell Proliferation and Differentiation: A Dissertation, Min Shi

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DNA Damage-Induced Apoptosis in the Presence and Absence of the Tumor Suppressor p53: A Dissertation, Laura Michelle McNamee

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Modulation of Voltage-Gated N-Type Calcium Channels by G Protein-Coupled Receptors Involves Lipids and Proteins: A Dissertation, Tora Mitra Ganguli

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The Molecular Mechanisms Underlying the Polarized Distribution of Drosophila Dscam in Neurons: A Dissertation, Shun-Jen Yang

Molecular Mechanism of RNA-Mediated Gene Silencing in Human Cells: A Dissertation, Chia-Ying Chu

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Structural and Functional Studies of the KCNQ1-KCNE K+ Channel Complex: A Dissertation, Steven D. Gage

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Checkpoint Regulation of S-Phase Transcription: A Dissertation, Chaitali Dutta

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Roles for Histones H4 Serine 1 Phosphorylation in DNA Double Strand Break Repair and Chromatin Compaction: A Dissertation, Melissa Anne Foley

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Chemical-Biological Investigation of KCNQ1/KCNE K+ Channel Complexes: A Dissertation, Trevor J. Morin

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Toll-Like Receptors: Target of Hepatitis C Virus: A Dissertation, Serena Soyoung Yunmee Chang

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GLUT1 Structure Function; Context, Ligand Cooperativity, and Mutagenesis Studies: A Dissertation, Trista K. Robichaud

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Role of MAP4K4 Signaling in Adipocyte and Macrophage Derived Inflammation: A Dissertation, Gregory J. Tesz

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Analysis of Protein Arginine Methyltransferase Function during Myogenic Gene Transcription: A Dissertation, Caroline S. Dacwag

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Role of Endoplasmic Reticulum Stress Response Signaling in T Cells: A Dissertation, Steven C. Pino

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Development of a Substrate with Photo-Modulatable Rigidity for Probing Spatial and Temporal Responses of Cells to Mechanical Signals: A Dissertation, Margo Tilley Frey

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Innate Immunity in Type 2 Diabetes Pathogenesis: Role of the Lipopolysaccharide Signaling Cascade: A Dissertation, James L. Young

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Role of Disulfide Bond Rearrangement in Newcastle Disease Virus Entry: A Dissertation, Surbhi Jain

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The Role of TEC Family Kinases in Innate T Cell Development and Function: a Dissertation, Martin Felices

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Small RNA Sorting in Drosophila Produces Chemically Distinct Functional RNA-Protein Complexes: A Dissertation, Michael D. Horwich

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Notch-1 and IGF-1 as Survivin Regulatory Pathways in Cancer: A Dissertation, Connie Wing-Ching Lee

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Analysis of CPEB Family Protein Member CPEB4 Function in Mammalian Neurons: A Dissertation, Ming-Chung Kan

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A Study of Cell Polarity and Fate Specification in Early C. Elegans Embryos: A Dissertation, Soyoung Kim

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The Humanized Mouse Model: The Study of the Human Alloimmune Response: A Dissertation, Marie A. King

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Plasma Membrane Localization of Signaling Proteins in Yeast: a Dissertation, Satoe Takahashi

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TLR Activation Prevents Hematopoietic Chimerism Induced by Costimulation Blockade: A Dissertation, David M. Miller

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Molecular Mechanisms of Neuropeptide Secretion from Neurohypophysial Terminals: a Dissertation, James M. McNally

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Mutations in the vpu and env Genes of HIV-1 Can Adversely Impact Infectivity: A Dissertation, Kathryn H. Richards

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Regulation of the NF-кB Precursor relish by the Drosophila I-кB Kinase Complex: A Dissertation, Deniz Erturk Hasdemir

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Epigenetic Determinants of Altered Gene Expression in Schizophrenia: a Dissertation, Hsien-Sung Huang

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The Role of Endoplasmic Reticulum Stress Signaling in Pancreatic Beta Cells: a Dissertation, Kathryn L. Lipson

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Newcastle Disease Virus Virulence: Mechanism of the Interferon Antagonistic Activity of the V Protein and Characterization of a Putative Virulence-Specific Antibody to the Attachment Protein: a dissertation, Judith G. Alamares

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Functional Analysis of Ing1 and Ing4 in Cell Growth and Tumorigenesis: a Dissertation, Andrew H. Coles

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Mitotic Response to DNA Damage in Early Drosophila Embroyos: a Dissertation, Seongae Kwak

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Modulation of Neuropeptide Release via Voltage-Dependent and -Independent Signaling in Isolated Neurohypophysial Terminals: a Dissertation, Cristina M. Velazquez-Marrero

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Molecular Dissection of the Cellular Reponse to Dengue Virus Infection, Rajas V. Warke

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Role of Host Cellular Membrane Raft Domains in the Assembly and Release of Newcastle Disease Virus: A Dissertation, Jason P. Laliberte

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Myocardial Macrophage Phenotypic Variation and Cytokine-Mediated Induction of HIV-Associated Cardiac Disease: A Dissertation, Jennifer Holmes Yearley

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Magnetic Resonance Imaging of the Rat Retina: a Dissertation, Govind Bhagavatheeshwaran

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Cross-Reactive Memory CD4+ and CD8+ T Cells Alter the Immune Response to Heterologous Secondary Dengue Virus Infections in Mice: A Dissertation, Coreen Michele Beaumier

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The Molecular Mechanisms of Activity-Dependent Wingless (Wg)/Wnt Signaling at a Drosophila Glutamatergic Synapse: a Dissertation, Bulent Ataman

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Dissecting Small RNA Loading Pathway in Drosophila melanogaster: A Dissertation, Tingting Du

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CD4 T Cell-Mediated Lysis and Polyclonal Activation of B Cells During Lymphocytic Choriomeningitis Virus Infection: A Dissertation, Evan Robert Jellison

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Attrition of CD8 T Cells during the Early Stages of Viral Infections: a Dissertation, Kapil Bahl

Publications from 2007

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A Role for Histone Modification in the Mechanism of Action of Antidepressant and Stimulant Drugs: a Dissertation, Frederick Albert Schroeder

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Surface of Yersinia pestis: LCRV, F1 Production, Invasion and Oxygen: A Dissertation, Kimberly Lea Pouliot

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Transcript-Specific Cytoplasmic Degradation of YRA1 Pre-mRNA Mediated by the Yeast EDC3 Protein: A Dissertation, Shuyun Dong

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Probing the Structural Topology of HIV-1 Virion Infectivity Factor (VIF): A Dissertation, Jared R. Auclair

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Molecular and Neuronal Analysis of Circadian Photoresponses in Drosophila: A Dissertation, Alejandro D. Murad

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Modulation of Cav1.3 L-Type Calcium Channels by Arachidonic Acid and Muscarinic M1 Receptors: A Dissertation, Mandy L. Roberts-Crowley

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A Genetic Analysis of Genomic Stability in Caenorhabditis Elegans: A Dissertation, Melissa M. Auclair

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Understanding Assembly of AGO2 RISC: the RNAi enzyme: a Dissertation, Christian B. Matranga

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Distinct Behaviors of Infected and Bystander Dendritic Cells Following Exposure to Dengue Virus: A Dissertation, Zachary Davis Nightingale

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Folding and Assembly of Multimeric Proteins: Dimeric HIV-1 Protease and a Trimeric Coiled Coil Component of a Complex Hemoglobin Scaffold: A Dissertation, Amanda Ann Fitzgerald

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Autoimmune Diabetes and Transplantation Tolerance Induced by Costimulation Blockade in NOD Mice: a Dissertation, Julie Lambert

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Role of Notch1 in Cardiac Cell Differentiation and Migration: A Dissertation, Dinh Le Mary Chau

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Transfer of the Ribosome-Nascent Chain Complex to the Translocon in Cotranslational Translocation: A Thesis, Ying Jiang

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Motor Property of Mammalian Myosin 10: A Dissertation, Kazuaki Homma

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Neural Diversity in the Drosophila Olfactory Circuitry: A Dissertation, Sen-Lin Lai

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Identification and Characterization of Agv1, a Pre-Metazoan Arf GAP: A Dissertation, Kimberly Renee Long

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Mechanism and Function of Actin Pedestal Formation by Enterohemorrhagic Escherichia coli O157:H7: A Dissertation, Michael John Brady

Maintenance of Constitutive and Inactive X Heterochromatin in Cancer and a Link to BRCA1: A Dissertation, Gayle Jeannette Pageau

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How Does ATP Regulate Erythrocyte Glucose Transport?: a Dissertation, Jeffry M. Leitch

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Molecular and Behavioral Analysis of Drosophila Circadian Photoreception and Circadian Thermoreception: A Dissertation, Ania Busza

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The Role of CD40 in Naïve and Memory CD8+ T Cell Responses: a Dissertation, Maria Genevieve H. Hernandez

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Cartilage tissue engineering: uses of injection molding and computer aided design for the fabrication of complex geometries with high dimensional tolerances: a dissertation, Morgan E. Hott

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Identification and Characterization of Components of the Intraflagellar transport (IFT) Machinery: a Dissertation, Yuqing Hou

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Cooperative Oncogenesis and Polyploidization in Human Cancers: A Dissertation, Susan Ann Heilman

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Functional and Structural Dissection of the SWI/SNF Chromatin Remodeling Complex: A Dissertation, Xiaofang Yang

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Collagen and Fibrin Bioplymer Microthreads for Bioengineered Ligament Generation: a Dissertation, Kevin Cornwell

The Role of CHD2 in Mammalian Development and Disease: a Dissertation, Concetta G. A. Marfella

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Interaction of a Mammalian Virus with Host RNA Silencing Pathways: A Dissertation, Bradford Michael Stadler

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Human Erythrocyte Glucose Transporter (GLUT1) Structure, Function, and Regulation: A Dissertation, David M. Blodgett

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Regulation of Cell Polarization and Map Kinase Signaling in the Saccharomyces Cerevisiae Pheromone Response Pathway: a Dissertation, Shelly Catherine Strickfaden

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The Argonaute Family of Genes in Caenorhabditis Elegans: a Dissertation, Erbay Yigit

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Rethinking Mechanisms of Actin Pedestal Formation by Enteropathogenic Escherichia Coli in the Context of Multiple Signaling Cascades: a Dissertation, Pamela Joyce Savage

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Characterization of the BACH1 Helicase in the DNA Damage Response Pathway: a Dissertation, Rachel Litman

Publications from 2006

Identification of Novel Interacting Proteins of Histone Gene Regulator, HINF-P: a Dissertation, Angela Miele

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Mechanisms of Endocytic Sorting: A Dissertation, Deborah Marie Leonard

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Quantitative Analysis of Hedgehog Gradient Formation Using an Inducible Expression System: a Dissertation, Vivian F. Su

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M1 Muscarinic Modulation of N-Type Calcium Channels: A Dissertation, John F. Heneghan

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RNA Silencing Pathways in Schizosaccharomyces pombe and Drosophila melanogaster: A Dissertation, Alla A. Sigova

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Requirements for Assembly and Release of Newcastle Disease Virus-Like Particles: A Dissertation, Homer Dadios Pantua

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IFN-α/β Induction by dsRNA and Toll-Like Receptors Shortens Allograft Survival Induced by Costimulation Blockade: A Dissertation, Thomas B. Thornley

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Serotype Cross-Reactive CD8+ T Cell Response to Heterologous Secondary Dengue Virus Infections in Humans: a Dissertation, Hema Sundara Bashyam

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Identification of Novel (RNAi Deficient) Genes in C. elegans: A Dissertation, Chun-Chieh G. Chen

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Probing Protein Dynamics Through Mutational and Computational Studies of HIV-1 Protease: A Dissertation, Jennifer E. Murzycki

The Role of Cell Adhesion, the Cytoskeleton, and Membrane Trafficking during Synapse Outgrowth: A Dissertation, James A. Ashley

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Light Intermediate Chain 1: a Multifunctional Cargo Binder for Cytoplasmic Dynein 1: a Dissertation, Thomas Wadzinski

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Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways: A Dissertation, Sarah R. Oikemus

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Genetic Dissection of the Neural Circuitry Underlying Memory Stability in Drosophila: A Dissertation, Alex Carl Keene

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Perturbation and Modulation of Microtubule Cytoskeletal Elements in Response to the Potentially Oncogenic Molecules, Survivin and P53, and Cytokinesis: A Dissertation, Jack Rosa

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Development of Pharmacological Magnetic Resonance Imaging Methods and their Application to the Investigation of Antipsychotic Drugs: a Dissertation, Karl F. Schmidt

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PLAGL2 Cooperates in Leukemia Development by Upregulating MPL Expression: A Dissertation, Sean F. Landrette

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Analysis of Toll-Like Receptor 4 Signal Transduction and IRF3 Activation in the Innate Immune Response: A Dissertation, Daniel C. Rowe

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Regulation of Contractility by Adenosine A1 and A2A Receptors in the Murine Heart: Role of Protein Phosphatase 2A: A Dissertation, Eugene I. Tikh

Translational Control of M Phase Progression: a dissertation, Kiran Padmanabhan

Multimodal MRI, Behavioral Testing, and Histology in a Rat Model of Transient Focal Cerebral Ischemia : A Dissertation, Kenneth M. Sicard

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SOX13, A γδ T Cell-Specific Gene, Is a WNT-Signaling Antagonist Regulating T Cell Development: A Dissertation, Heather J. Melichar

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Characterization of the Relationship Between Measles Virus Fusion, Receptor Binding, and the Virus-Specific Interaction Between the Hemagglutinin and Fusion Glycoproteins: a Dissertation, Elizabeth Ann Corey

Characterization of Novel Lymphoid-Associated Genes Identified by Gene-Trapping: a Dissertation, Pamela James

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Rb Inactivation Leads to E2F1-mediated DNA Double Strand Break Accumulation: A Dissertation, Mary Theresa Pickering

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Transcriptional Regulation During Adipocyte Differentiation: A Role for SWI/SNF Chromatin Remodeling Enzymes: A Dissertation, Nunciada Salma

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Posttargeting Events in Cotranslational Translocation Through the Sec61 Complex: a Thesis, Zhiliang Cheng

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Dissecting the Mechanism for the Selective Induction of Apoptosis in Transformed Cells by CAV Apoptin: a Dissertation, Destin W. Heilman

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Analysis of the Role of Cytosolic Aminopeptidases in the Generation of MHC-Class I Presented Peptides: a Dissertation, Charles Fenton Towne

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Human Rad51: Regulation of Cellular Localization and Function in Response to DNA Damage: A Dissertation, Brian Thomas Bennett

Publications from 2005

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Characterization of the Interaction Between the Attachment and Fusion Glycoproteins Required for Paramyxovirus Fusion: a Dissertation, Vanessa R. Melanson

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The Role of Tec Kinases in CD4+ T Cell Activation: A Dissertation, Cheng-Rui Michael Li

Structural Determinants of Phosphoinositide Recognition by Grp1 Family Pleckstrin Homology Domains: a Dissertation, Thomas Charles Cronin

Biophysical Analysis of the Human Erythrocyte Glucose Transporter: a Dissertation, Christopher A. Graybill

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Regulation of Life Span by DAF-16/Forkhead Transcription Factor in Caenorhabditis elegans: A Dissertation, Seung Wook Oh

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CD4+ T Cell Responses: A Complex Network of Activating and Tolerizing Signals as Revealed by Gene Expression Analysis: A Dissertation, David Spaulding Brown

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Regulation of Cell Growth and Differentiation within the Context of Nuclear Architecture by the Runx2 Transcription Factor: a Dissertation, Daniel W. Young

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The Identification of Cooperating Mutations in TAL1-Mediated Leukemia in the Mouse: A Dissertation, Jennifer Ann Calvo

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Biochemical Mechanism of RNA Interference in Higher Organisms: A Dissertation, Dianne S. Schwarz

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A Biochemical Dissection of the RNA Interference Pathway in Drosophila melanogaster: A Dissertation, Benjamin Haley

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Characterization of JNK Binding Proteins: A Dissertation, Jeffrey Scott Rogers

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Chemokine Induction by Dengue Virus Infection: Mechanisms and the Role of Viral Proteins: a Dissertation, Carey L. Medin

Mechanisms of Host Cell Attachment by the Lyme Disease Spirochete: A Dissertation, Joshua Richard Fischer

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Egr-2 and PD-1 Are Required for Induction and Maintenance of T Cell Anergy: A Dissertation, Kenneth D. Bishop

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Mechanisms of Host-Range Function of Vaccinia Virus K1L Gene: a Dissertation, Ritu Rakshit Bradley

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Cross-Reactive CD8 T Cell Responses and Heterologous Immunity During Acute Epstein-Barr Virus Infection: a Dissertation, Shalyn Catherine Clute

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Functions of the Cdc14-Family Phosphatase Clp1p in the Cell Cycle Regulation of Schizosaccharomyces pombe: A Dissertation, Susanne Trautmann

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Cytoplasmic Localization of HIV-1 Vif Is Necessary for Apobec3G Neutralization and Viral Replication: A Dissertation, Melissa Ann Farrow

NMR Characterization of Pathological Disease States: Monitoring Response to Single-Dose Radiotherapy in a RIF-1 Tumor Model and the Role of Spreading Depression in the Evolution of Ischemic Stroke: a Dissertation, Erica C. Henning

The Function of Myosin IX: the Ninth Class of Myosin Superfamily: a Dissertation, Nobutaka Saeki

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The Epigenetic Silencing of PMP24 During the Progression of Prostate Cancer from an Androgen-Dependent to Androgen-Independent State in the LNCAP Cell Model: a Dissertation, Mengchu Wu

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Analysis of Polarity Signaling in Both Early Embryogenesis and Germline Development in C. Elegans: A Dissertation, Yanxia Bei

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Regulation and Function of Stress-Activated Protein Kinase Signal Transduction Pathways: A Dissertation, Deborah Marie Brancho

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The Role of Itk in T Cell Development: A Dissertation, Julie Ann Lucas

The Human Rev Interacting Protein (hRIP) is Required for Rev Function and HIV-1 Replication: a Dissertation, Nuria Sánchez-Velar

Publications from 2004

Alcohol Modulation of Human BK Channels Evidence for β-Subunit Dependent Plasticity in Functional Ethanol Tolerance: A Dissertation, Paula Leslie Feinberg-Zadek

Human PC4 Prevents Mutagenesis and Killing by Oxidative DNA Damage: a Dissertation, Jen-Yeu Wang

Role of the JNK Signal Transduction Pathway in Cell Survival: a Dissertation, Jennifer A. Lamb

Wnt8 Is a Novel Target of the Dorsal/Twist/Snail Network and an Inhibitor of Dorsal in the Gastrulating Drosophila Embryo: A Dissertation, Atish Ganguly

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Regulation and Function of Runx2 During Chondrogenic and Osteogenic Differentiation: a Dissertation, Christopher J. Lengner

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The Roles of DNA Mismatch Repair and Recombination in Drug Resistance: A Dissertation, Melissa A. Calmann

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Prevention of Oxidative Damage by Yeast and Human OXR1: A Dissertation, Nathan Andrew Elliott

The Role of RIP1 in the TNFR1 Signal Transduction Pathway: a Dissertation, Thomas H. Lee

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Macrophages Directly Prime Naïve CD8+ T Cells: a Dissertation, Lu-Ann M. Pozzi

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The role of Janus Kinase 3 in CD4+ T Cell Homeostasis and Function: A Dissertation, Shane Renee Mayack

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Centrosomes in Cytokinesis, Cell Cycle Progression and Ciliogenesis: a Dissertation, Agata Jurczyk

Convergent Biochemical and Biomechanical Pathways in Tissue Remodeling: The Role of α₂β₁ Integrin and MMP Activity: A Dissertation, Jonathan Adam Phillips

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The Role of ITK and RLK in CD8+ T Cell Development and Function: a Dissertation, Luana O. Atherly

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Functional and Structural Analysis of the Yeast SWI/SNF Complex: a Dissertation, Corey Lewis Smith

Signaling Events Leading to CPEB-Mediated Translation: a Dissertation, Madathia Sarkissian

Crystallographic Studies of Rrythrocruorin from Lumbricus Terrestris: a Dissertation, Kristen Strand-Tibbitts

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Changes in Polymer, Scaffold, and IGF-I Delivery Methods Directly Affect Cartilage Tissue Development: A Dissertation, Nichole Renee Mercier

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Midbody Anchoring of SNARE and Exocyst Complexes by Centriolin is Required for Completion of Cytokinesis: A Dissertation, Adam Scott Gromley

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Association of Pericentrin with the γ Tubulin Ring Complex: a Dissertation, Wendy Cherie Zimmerman

Mdm2 and Mdm4 Functions in Growth Control: a Dissertation, Heather Anne Steinman

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Functional MRI of Rat and Monkey Models of Absence Epilepsy: A Dissertation, Jeffrey R. Tenney

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The Role of γс Cytokines in T Cell Development, T Cell Homeostasis and CD8+ T Cell Function: A Dissertation, Sara Gozalo

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Channel Specific Calcium Dynamics in PC12 Cells: A Dissertation, Keith Tully

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Pathways Linking Deregulated Proliferation to Apoptosis: a Dissertation, Harry A. Rogoff

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Structural Basis for Rab5 Activation and Effector Specificity in Endosome Tethering: A Dissertation, Eric Lee Merithew

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Homologous Recombinational DNA Repair: from Prokaryotes to Eukaryotes: a Dissertation, Anthony L. Forget

Analysis of Mitochondrial Remodeling in Adipocytes during Adipogenesis and Obesity Development: a Dissertation, Leanne Wilson-Fritch

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Novel Insights into Schwann Cell Dynamics in Peripheral Nervous System Myelination: a dissertation, Cheryl Lynn Gatto

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EBV-Specific CD4+ T Cell Responses in Acute Infectious Mononucleosis: a Dissertation, Melissa Lynn Precopio

Organ-Dependent and Epitope-Dependent Repertoire Usage and Apoptosis of Antigen-Specific T Cells in Viral Infections: a Dissertation, Xiaoting Z. Wang

Analysis of FYVE Domain-Containing Proteins in Signaling and Endocytosis: a dissertation, Susan J. Hayes

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Upregulation of Heme Pathway Enzyme ALA Synthase-1 by Glutethimide and 4,6-Dioxoheptanoic Acid and Downregulation by Glucose and Heme: A Dissertation, Sridevi Kolluri

Role of the Sid2-Mob1 Kinase Complex in Controlling the Onset of Cytokinesis in the Fission Yeast Schizosaccharomyces Pombe: a Dissertation, Ming-Chin Hou

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The Structural Basis for the Phosphorylation-Induced Activation of Smad Proteins: a Dissertation, Benoy M. Chacko

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Expression of rag2 and V(D)J Recombinase Activity are Reduced in Aged Mice as a Result of Changes in the Bone Marrow Microenvironment: a Dissertation, Joseph E. Labrie III

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Mechanisms of TAL1 Induced Leukemia in Mice: A Dissertation, Jennifer Elinor O'Neil

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Chlamydomonas Reinhardtii ODA5 Encodes an Axonemal Protein Required for Assembly of the Outer Dynein Arm and an Associated Flagellar Adenylate Kinase: A Dissertation, Maureen Wirschell

Role of Virus-Specific CD8+ T Cells in the Severity of Hantavirus Pulmonary Syndrome: A Dissertation, Elizabeth D. Kilpatrick

Publications from 2003

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Essential Roles of the Meis Family Proteins During Segmentation of the Zebrafish Hindbrain : a Dissertation, Seong-Kyu Choe

Role of Intimin and Tir in Actin Signalling by Enterohemorrhagic and Enteropathogenic Escherichia coli: A Dissertation, Padhma Radhakrishnan

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Function of the Zinc-Finger Repressor NLZ in the Developing Zebrafish Hindbrain: a Dissertation, Alexander Peter Runko

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Regulation of Zebrafish Hindbrain Development by Fibroblast Growth Factor and Retinoic Acid: A Dissertation, Nicole Marie Roy

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Poly(ADP)-Ribose Polymerase Activity in the Eukaryotic Mono-ADP-Ribosyl Transferase, ART2: a Dissertation, Alan R. Morrison

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Conserved Nucleosome Remodeling/Histone Deacetylase Complex and Germ/Soma Distinction in C. elegans: A Dissertation, Yingdee Unhavaithaya

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Chondrocyte Adhesion to RGD-bonded Alginate: Effect on Mechanotransduction and Matrix Metabolism: a Dissertation, Nicholas G. Genes

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The Function of the Tyrosine Kinase, Itk, in CD4+ T Cell Differentiation and Death: a Dissertation, Andrew Todd Miller

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The Molecular Mechanisms of T Cell Clonal Anergy: A Dissertation, John E. Harris

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Cholesterol and Phospholipid Modulation of BK[subscript Ca] Channel Activity and Ethanol Sensitivity: a dissertation, John J. Crowley

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MHC Class I Antigen Presentation is Regulated by the SUMO-Conjugating Enzyme UBC9: a Dissertation, Yuelei Shen

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Mechanistic Analysis of Chromatin Remodeling Enzymes: a Dissertation, Mariela Jaskelioff

DC3, a Calcium-Binding Protein Important for Assembly of the Chlamydomonas Outer Dynein Arm: a Dissertation, Diane M. Casey

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Actin Pedestal Formation on Mammalian Cells by Enteropathogenic Escherichia coli: A Dissertation, Kenneth Geno Campellone

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CD40-CD154 Blockade Facilitates Induction of Allogeneic Hematopoietic Chimerism and Transplantation Tolerance: A Dissertation, Edward Seung

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Mechanics of Fibroblast Migration: a Dissertation, Steven Munevar

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Peptidyltransfer Reaction Catalyzed by the Ribosome and the Ribozyme: a Dissertation, Lele Sun

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Involvement of CDP/Cux in the Regulation of Histone H4 Gene Expression, Proliferation and Differentiation: a Dissertation, Mai X. Luong

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T Cell Immunity and HIV-1 Replication in Vertically-Infected Infants and Children: A Dissertation, Zachary Aaron Scott

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Role of c-Jun NH-terminal Kinase in Bcr/Abl Induced Cell Transformation: a dissertation, Patricia M. Hess

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Intranuclear Trafficking of RUNX/AML/CBFA/PEBP2 Transcription Factors in Living Cells: A Dissertation, Kimberly Stacy Harrington

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The Genetic Basis of Resistance to Transplantation Tolerance Induced by Costimulation Blockade in NOD Mice: a Dissertation, Todd Pearson

Function of Cytoskeletal Proteins in GLUT4 Vesicle Transport in Adipocytes: Dissertation, Jin Gyoon Park

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The Role of the SWI/SNF Component INI1 in Mammalian Development and Tumorigenesis: a Dissertation, Cynthia J. Guidi

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HIV-1 Gene Expression: Transcriptional Regulation and RNA Interference Studies: a Dissertation, Ya-Lin Chiu

Design and Performance of a Localized Fiber Optic, Near-Infrared Spectroscopic Prototype Device for the Detection of the Metabolic Status of "Vulnerable Plaque": in-vitro Investigation of Human Carotid Plaque: a Dissertation, Tania N. Khan

Novel, Functional Interactions Between TrkA Kinase and p75 Neurotrophin Receptor in Neuroblastoma Cells: A Dissertation, Peter J. Condon

Publications from 2002

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Autoantibodies to Centrosomes are Diagnostic for Human Scleroderma and Can Be Induced by Experimental Mycoplasma Infection in Mice: A Dissertation, Irina Catrinel Gavanescu

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Activation and Role of Memory CD8 T Cells in Heterologous Antiviral Immunity and Immunopathology in the Lung: A Dissertation, Hong Chen

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Mechanisms Contributing to Transcriptional Regulation and Chromatin Remodeling of the Bone Specific Osteocalcin Gene, Soraya Elisa Gutierrez Gallegos

Coordinating Cytokinesis with Mitosis by a Conserved Signal Transduction Network in the Fission Yeast Schizosaccharomyces Pombe: a Dissertation, David A. Guertin

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The Role of Human Cytomegalovirus Immediate Early Proteins in Cell Growth Control: A Dissertation, Jonathan Patrick Castillo

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Roles of Lissencephaly Gene, LIS1, in Regulating Cytoplasmic Dynein Functions: a Dissertation, Chin-Yin Tai

The Apoptotic Activity of c-Jun NH2-Terminal Kinase Signal Transduction: A Dissertation, Kui Lei

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The Human Rad52 Protein: a Correlation of Protein Function with Oligomeric state: a Dissertation, Janice A. Lloyd

Altering the Tropism of Retroviral Vectors For In Vivo Gene Therapy: Pseudotyped Virus Targeting by Ligand-Receptor Interactions: A Dissertation, Timothy J. Gollan

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Viral Abrogation of Stem Cell Transplantation Tolerance Causes Graft Rejection and Host Death by Different Mechanisms: A Dissertation, Daron Forman

The Role of Dbp2p in Both Nonsense-Mediated mRNA Decay and rRNA Processing: A Dissertation, Andrew Thomas Bond

Actin Reorganization in Drosophila Syncytial Blastoderm Embryos: a Dissertation, Victoria A. Stevenson,

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A Characterization of Substrates and Factors Involved in Yeast Nonsense-Mediated mRNA Decay: A Dissertation, Jonathan Philip Belk

Publications from 2001

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Estrogen and Antiestrogen Actions on Human Prostate Cancer: A Dissertation, Kin-Mang Lau

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Regulation of Nuclear Hormone Receptors by Corepressors and Coactivators: a Dissertation, Xiaoyang Wu

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Analysis of RNA Interference in C. elegans: A Dissertation, Alla Grishok

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Snail Protein Family in Drosophila Neurogenesis: a Dissertation, Shovon I. Ashraf

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Oligomerization and Endocytosis of the α-Factor Receptor: A Dissertation, Ayce Yesilaltay

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Long-Lived Memory T Lymphocyte Responses Following Hantavirus Infection: a Dissertation, Heather Lin Van Epps

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Mechanisms of Establishment and Maintenance of RNA Virus Persistence in Primary Lymphocytes: a Dissertation, Mark S. Cabatingan

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Stress Activated Protein Kinase Regulation of Gene Expression in Apoptotic Neurons: A Dissertation, Gerard S. De Zutter

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Role of the Intestinal Immune System in the Pathogenesis of Autoimmune Diabetes in the BB Rat Model of Type 1 Diabetes Mellitus, Derrick James Todd

Members of the Meis/Prep Family Synergize: with Pbx4 and Hoxb1b in Prompting Hindbrain fates in the zebrafish, Nikolaos Vlachakis

Visualization of Single RNA Transcripts in situ: A Dissertation, Andrea M. Femino

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Modulation of N-type Calcium Channels in Rat Superior Cervical Ganglion Neurons: A Dissertation, Curtis F. Barrett

Mitotic Roles for Cytoplasmic Dynein and Implications for Brain Developmental Disease: a Dissertation, Nicole E. Faulkner

The Role of the Unconventional Myosin Motor Protein, Myosin 5a, in Thyroid Hormone Mediated Actin-Based Vesicle Trafficking: a Dissertaion, Stanley J. Stachelek

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The Yeast SWI/SNF Complex Structure and Function: A Dissertation, Joan Frances Flanagan

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Ethanol Tolerance in the Rat Neurohypophysis: a Dissertation, Thomas K. Knott

Publications from 2000

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The Regulation of nNOS During Neuronal Differentiation and the Effect of Nitric Oxide on Hdm2-p53 Binding: a Dissertation, Christopher M. Schonhoff

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A Study on the Cellular Localization of Factors Involved in Yeast Nonsense-Mediated mRNA Decay and their Mechanisms of Control on Nonsense mRNA Translation: a Dissertation, Alan Baer Maderazo

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The Role of MKK3 in Mediating Signals to the p38 MAP Kinase Pathway: A Dissertation, Mark Allen Wysk

Characterization of Intrahepatic T-lymphocytes in Patients with Chronic Hepatitis C Virus Infection: a Dissertation, Vicki M. Giuggio

Structural and Mutational Analysis of Rab2A Activation by Mss4: A Dissertation, Zhongyuan Zhu

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Differential Mechanisms of Nuclear Receptor Regulation by the Coactivator RAC3: A Dissertation, Christopher Leo

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CIS/SOCS Proteins in Growth Hormone Action: A Dissertation, Ling Du

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Mutational Analysis of the MutH from Escherichia Coli: a Dissertation, Tamalette Loh

Induction and Maintenance of Transplantation Tolerance by Treatment with a Donor Specific Transfusion and Anti-CD154 mAb: a Dissertation, Neal N. Iwakoshi

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In Vitro and in vivo Studies of Murine Polytropic Retrovirus Infections: a Dissertation, Scott A. Loiler

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Conserved Features of Chromatin Remodeling Enzymes: A Dissertation, Laurie A. Boyer

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Allosteric Regulation of Recombination Enzymes E. coli RecA and Human Rad51: A Dissertation, Julie Kelley De Zutter

The Functional Roles of the Human Immunodeficiency Virus Type-1 Matrix Protein during Viral Life Cycle: A Dissertation, Stefan A. Dupont

Human Lymphocyte Engraftment and Function in HU-PBL-SCID Mice: a Dissertation, Eric James Wagar

Regulation of Immunoglobulin Germline ε Transcripts by IL-4, CD40 Ligand and Lipopolysaccharide via Stat6, AP-1 and NF-кB Transcription Factors: A Dissertation, Ching-Hung Shen

Regulation of the Transfer of the Ribosome-Nascent Chain Complex from the Signal Recognition Particle to the Translocation Channel: a Thesis, Weiqun Song

Intimin-Tir Interaction in Enterohemorrhagic E. coli: A Dissertation, Hui Liu

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Characterization of Immune Responses Following Neonatal DNA Immunization: A Dissertation, Tamera Marie Pertmer

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The Role of the Light Intermediate Chains in Cytoplasmic Dynein Function: a Dissertation, Sharon H. Tynan

DNA Immunization: Basic Mechanisms of the DNA-Raised Antibody Response Using an Influenza Hemagglutinin-Expressing Plasmid: A Dissertation, Christine Margaret Boyle

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Sequences Required for Neurotensin Receptor-1 Gene Expression in N1E-115 Neurosblastoma Cells: Critical Importance of a CACCC Element for Activation During DMSO-Induced Neuronal Differentiation: a Dissertation, Daniel Jorge Tavares

Interaction Between Ribosome-Nascent Chain and sec61 Complexes and Their Role in the Translocation of Proteins Across the Endoplasmic Reticulum Membrane: a Thesis, David Raden

Publications from 1999

Pericentrin and Gamma Tubulin Form a Novel Lattice and a Protein Complex that is an Essential Unit of Centrosome Assembly: a Dissertation, Jason B. Dictenberg

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Identification of the Human Erythrocyte Glucose Transporter (GLUT1) ATP Binding Domain: A Dissertation, Kara B. Levine

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Analysis of Cell Polarity Signaling in C. elegans: A Dissertation, Christian Ernest Rocheleau

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The CTL Memory Responses to Influenza A Viruses in Humans: a Dissertation, Julie Marie Jameson

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Mechanisms of Newcastle Disease Virus-Mediated Membrane Fusion: A Dissertation, Judith Stone-Hulslander

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Characterization of the Molecular Mechanisms Regulating the Agrin Signaling Pathway: a Dissertation, Laura Jalso Megeath

Rel Related Proteins and MAP Kinase p38 in Regulating Drosophila Immunity: a Dissertation, Zhiqiang Han

A Study of the Assembly Mechanism of Pericentrin and γ Tubulin onto the Centrosome in Mammalian Cells: A Dissertation, Aaron Isadore Young

The Role of Translation Initiation in Nonsense-Mediated mRNA Decay in the Yeast Saccharomyces Cerevisiae: a Dissertation, Ellen Marie Welch

Quality Control of Plasma Membrane Proteins: A Dissertation, Yu Li

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Characterization, Mechanisms and Modulation of Calcium Signals in Glia: a Dissertation, Andreja Strahonja

ATP Regulation of Erythrocyte Sugar Transport: a Dissertation, Karen Schray Heard

UAP56: A Dead Box Protein Required for Pre-mRNA Splicing: A Dissertation, Meng Zhang

Evolution of the T Cell Receptor Repertoire during and after Viral Infection: a Dissertation, Lin Meei-Yun

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Structural and Signaling Proteins at the Synapse: Dystroglycan & Insulin Receptor Tyrosine Kinase Substrate p58/53: a Dissertation, Mary-Alice Abbott

Intracellular Hairpin Ribozyme Catalysis: a Dissertation, Christine Patricia Donahue

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Human T Cell Responses to Dengue Virus Infections: CD8+CTL and Acute Immunosuppression: a Dissertation, Anuja Mathew

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mRNA Poly(A) tail: a 3' Enhancer of Translational Initiation: a Thesis, David Munroe

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The Virus-Specific CD4+ T Cell Response During Acute Lymphocytic Choriomeningitis Virus Infection and into Long Term Memory: a Dissertation, Steven Michael Varga

Publications from 1998

Alcohol Modulation of N-methyl-D-aspartate Gated Receptor/Channels and Large Conductance Calcium-Activated Potassium Channels: a Dissertation, Benson Chu

Characterization of a Deletion in erb [subscript erb]B Sequences Associated with Angiosarcoma: a Thesis, Sharon Elizabeth Tracy

The ADA/GCN5 Containing Acetyltransferase Complexes of Saccharomyces cerevisiae: Roles in Antagonizing Chromatin Mediated Transcriptional Repression: A Dissertation, Kerri Jeanne Pollard

DNA Immunization: Role of Target Site, Bone Marrow-Derived Cells and Secretion of Antigen in the Initiation of Immune Responses: A Dissertation, Celia Aurora Tiglao Torres

CD40 Sustains T Cell Activation During Cognate Communication with Resting B Cells: a Dissertation , Dean E. Evans

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Role of MAP Kinases in the Induction of Heme Oxygenase-1 by Arsenite: Studies in Chicken Hepatoma Cells: A Dissertation, Kimberly Kirstin Elbirt

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Structural Association of XIST RNA with Inactive Chromosomes in Somatic Cells : a Key Step in the Process that Establishes and Faithfully Maintains X-inactivation, Christine Moulton Clemson

Human Cellular Immune Responses to Dengue Virus Infection: Potential Roles in Immunopathology, Susan J. Gagnon

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Transcriptional Regulation of a Human H4 Histone Gene is Mediated by Multiple Elements Interacting with Similar Transcription Factors: A Dissertation, Thomas J. Last

Development of the Antibiotic Potential of a Unique Family of DNA Polymerase Inhibitors, Paul M. Tarantino,

The Osteocalcin Gene: Transcriptional Elements and Factors Regulating TGF-β1 Responsiveness and Tissue-Specific Expression in Bone Cells: A Dissertation, Chaitali Banerjee

Helper T Cell Differentiation in DNA-Immunized Mice: A Dissertation, David Marc Feltquate

Cloning, Characterization and Functional Analysis of TPR, an Oncogene-Activating Protein of the Nuclear Pore Complex: A Dissertation, Peter Lawrence Bangs

Mechanism of inhibition of B family DNA polymerases by N²-([rho]-n-butylphenyl)-2'-deoxyguanosine 5'-triphosphate, BuPdGTP: A Dissertation, James Michael Walker Stattel

Envelope Determinants of HIV-1 Cytopathicity, Serene E. Forte

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Analysis of the Mechanism of Ras Activation: Mapping of Important Functional Domains of the Son of Sevenless Protein, Linda Sue McCollam-Guilani

Crystallographic Studies of the Pathological Polymerization of Human Hemoglobin, Daniel John Harrington

T Cell Receptor-Dependent and Independent Events During Potent Anti-Viral T Cell Responses, Christopher C. Zarozinski

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Cloning and Characterization of Dynamitin, the 50 kDa Subunit of Dynactin: A Study of Dynactin and Cytoplasmic Dynein Function in Vertebrates, Christophe de Jesus Echeverri

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Genetic and Biochemical Analysis of the Activation Mechanism of the Saccharomyces Cerevisiae Pheromone Receptor, Gul H. Bukusoglu

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Analysis of TAF II Function in the Yeast Saccharomyces Cerevisiae, Lynne Marie Apone

The Ability of CD40L, but not LPS, to Induce Germline Immunoglobulin γ1 Transcripts Is Explained by Differential Induction of NF-κB/Rel Proteins , Shih-Chang Lin

Publications from 1997

HIV-1 and SIVmac Repression by Retinoic Acid in Monocyte Cell Lines and Macrophages, and HIV-1 Repression by Interleukin-16 in T Cell Lines: A Dissertation, Joseph Walter Maciaszek

The c-Jun NH₂-Terminal Kinase Regulates Jun in vitro and in vivo during the Process of Dorsal Closure: A Dissertation, Hayla Karen Sluss

Mechanism of Fatty Acid Modulation of Calcium-Activated Potassium Channel Activity, Alison L. Clarke

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An Examination of the Hypothalamo-neurohypophysial System of the Rat: Restoration of the Vasopressinergic System, Lynn M. DiBenedetto

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Studies of Leishmania major Pteridine Reductase 1, a Novel Short Chain Dehydrogenase, James Luba

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In Vivo Functional Analysis of the Saccharomyces Cerevisiae SWI/SNF Complex: A Dissertation, Loree Griffin Burns

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In Vivo Regulation of Murine Cytomegalovirus Infections: The Role of Cell Surface Molecules and Mechanisms of Control by Natural Killer Cells: A Dissertation, Chin Hun Tay

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Contribution of Ordered Water Molecules and a Crucial Phenylalanine to Cooperative Pathway(s) in Scapharca Dimeric Hemoglobin: a Dissertation, Animesh Dev Pardanani

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Molecular Basis of the Mechanism and Regulation of Receptor-GTP Binding Protein Interactions: A Thesis, Marianne Wessling-Resnick

The Role of Ca2+ Channel Subunit Composition in G Protein-Mediated Inhibition of Ca2+ Channels: a Disstertation, John Patrick Roche

Publications from 1996

Signal Transduction by the EGF Receptor in Normal and Transformed Cells: a Dissertation, Cherie A. Taglienti

Characterization of DNA-Protein Interactions at the NT/N Promoter: Proles for AP-1 and ATF Proteins, Gerard P. McNeil

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Mismatch Repair Acts As a Barrier to Homeologous Recombination in Saccharomyces cerevisiae: A Dissertation, Erica Marie Selva

A Potential Role for the 70 kD Heat Shock Cognate Protein in Receptor Endocytosis, Victor Lazaron

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Neuroprotection and Neurotransplantation Strategies in Models of Parkinson’s Disease, Wendy R. Galpern

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Cytotoxic T-Lymphocyte Responses During Acute Epstein-Barr Virus Infection, Brian L. Beaulieu

Dissection of Lymphocyte Activation: Defining a Role for PI-3 Kinase, David Alan Hartley

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Analysis of Low Zone Tolerance in Normal and B Cell-Deficient Mice, Allison Michelle Baird

Publications from 1995

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Type-Specific Immunity in HIV-1 Vertically Infected Infants, Cheryl A. Pikora

R T 6: a Bifunctional Protein of Regulatory T Cells, Mark R. Rigby

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Chromatin Structure of the Rat Osteocalcin Gene Promoter in Bone-Derived Cells, Martin A. Montecino

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Molecular Characterization of Mitofilin, a Novel, Mitochondrial, Coiled Coil Protein, and the Relationship Between Organism Complexity and Coiled Coil Protein-Mediated Structure: A Dissertation, Paul R. Odgren

Tolerance Induction to a Foreign Protein Antigen: Analysing the Role of B Cells in Establishing Peripheral Tolerance, Victoria Nicole Yuschenkoff

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Cloning and Cell Cycle Analysis of NuMA, a Phosphoprotein That Oscillates Between the Nucleus and the Mitotic Spindle, Cynthia A. Sparks

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The Role of T Lymphocytes in the hu-PBMC-SCID Mouse Model of Epstein-Barr Virus-Associated Lymphoproliferative Disease, Mary A. Cromwell

The Characterization of Staphylococcus Aureus polC: the Structural Gene for DNA Polymerase III, Diane Frances Pacitti

Publications from 1994

T Lymphocyte Apoptosis and Memory in Viral Infection: A Dissertation, Enal Shahid Razvi

Identification and Characterization of the Murine Germline Immunoglobulin Heavy Chain Epsilon Constant Region Promoter, Sandra Ann Delphin

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Signal Transduction Mechanisms for the Stimulation of Lipolysis by Growth Hormone: A Dissertation, Rupert G. Yip

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Studies on the Mechanism of Deoxycytidylate Hydroxymethylase from Bacteriophage T4: A Dissertation, Karen Lorraine Graves

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Transcriptional Regulation by the SACCHAROMYCES CEREVISIAE Centromere-Binding Protein CP1: a Dissertation, Kevin F. O'Connell

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Human Immunodeficiency Virus Type-1 Infection of Human Myeloid Cells, Cynthia Ann Pise-Masison

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Molecular Determinants of GLUT1: Structure and Function: A Dissertation, Ralph J. Zottola

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Osteoclast Ontogeny-Experimental Studies in Two Osteopetrotic Mutations in the Rat: A Dissertation, Matthew Joseph Cielinski

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A Mutational Analysis of Structural Determinants Within the Newcastle Disease Virus Fusion Protein: a Dissertation, Julie N. Reitter

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Analysis of Temperature Sensing in Yersinia pestis: A Dissertation, Nancy Palme Hoe

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Cloning, Expression and Regulation of CYP3A10, a Hamster Liver Cytochrome P450 Involved in Lithocholic Acid and Steroid 6β-Hydroxylation: a Dissertation, Jose Manuel Teixeira

Publications from 1993

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Analysis of and Role for Effector and Target Cell Structures in the Regulation of Virus Infections by Natural Killer Cells: a Dissertation, Randy R. Brutkiewicz

Cytotoxic T lymphocyte specificities during the acute and memory responses to lymphocytic choriomeningitis virus infection : ‡b a dissertation, Sharon R. Nahill

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Regulation of IgA Class Switch Recombination in the I.29μ B Cell Lymphoma by Cytokines and Inhibitors of Poly(ADP-ribose) Polymerase: A Thesis, Penny E. Shockett

Analysis of CD45 Alternative Exon Expression in Murine and Human CD4+ T Cell Subpopulations: a Thesis, Paul R. Rogers

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sieB and esc genes of Bacteriophage P22: A Dissertation, Koustubh Ranade

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Transport of Nucleotide Derivatives into Endoplasmic Reticulum and Golgiapparatus Derived Vesicles: a Dissertation, Caroline A. Clairmont

Metabolic Regulation of Glucose Transport is an Insulin-Dependent Mechanism: A Dissertation, Deborah L. Diamond

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Virus-Host Interactions in the Development of Avian Leukosis Virus-Induced Osteopetrosis: a Dissertation, Rosalinda Gram Foster

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Regulation of δ-Aminolevulinic Acid Synthase and Heme Oxygenase in Cultured Chick Embryo Liver Cells: Synergistic Induction of Both Enzymes by Glutathimide and Iron and Repression of δ-Aminolevulinic Acid Synthase by Metalloporphyrins and Heme: A Dissertation, Edward Earl Cable

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Dynamics of Neuron-Specific Gene Expression During Development and in Response to Selective Lesions of the Rat Central Nervous System: A Dissertation, Richard H. Melloni

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Nuclear Structure Studied by Fluorescence Hybridization: Visualization of Individual Gene Transcription and RNA Splicing: A Thesis, Yigong P. Xing

Analysis of the EGF Receptor Homologue in Drosophila: a Thesis, Sandra Marie McNeil

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Genetic Analysis of the Saccharomyces Cerevisiae Centromere-Binding Protein CP1: a Thesis, Daniel C. Masison

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HIV-1 Sequences in the Establishment of Chronic Virus Producers: a Thesis, Farah Mustafa

Publications from 1992

Functional Analysis of the c-MYC Transactivation Domain: A Dissertation, Alpna Seth

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Development and Application of Ultrastructural in Situ Hybridization to Visualize the Spatial Organization of mRNA: a Dissertation, Gary J. Bassell

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Characterization of the Hypersensitive Response of Glycogen Phosphorylase to Catecholamine Stimulation in Primary Culture Diabetic Cardiomyocytes: A Thesis, Jo Ann Buczek-Thomas

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Structure and Function of Cytoplasmic Dynein: a Thesis, Bryce M. Paschal

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Distinct Permissive Pathways Mediate the Effects of Nerve Growth Factor and Lithium on Neurotensin/Neuromedin N Gene Expression in PC12 Cells: A Thesis, Bryant Paul Bullock

DNA Sequences Involved in Immunoglobulin Germ-line C [alpha] Gene Transcription: a Thesis, Yi-chaung A. Lin

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Probing the dNTP Binding Region of Bacillus subtilis: DNA Polymerase III with Site-Directed Inhibitors: A Dissertation, Michelle Marie Butler

Publications from 1991

Ribosome Binding to the Mammalian Endoplasmic Reticulum: A Thesis, Paula Grosse Collins