Department of Medicine, Division of Gastroenterology
Digestive System Diseases | Gastroenterology | Hepatology | Immunopathology
Immune and inflammatory pathways have a central role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Both the innate and adaptive immune systems contribute to the development of NAFLD. Pathogen-associated molecular patterns and danger-associated molecular patterns are known to activate a variety of pattern-recognition receptors that result in inflammation. The key features of the immune system and inflammatory pathways in the development of NAFLD are discussed in this review.
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Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
DOI of Published Version
Hepatol Int. 2013 Aug 30;7(Suppl 2):771-781. Link to article on publisher's site
Ganz M, Szabo G. (2013). Immune and inflammatory pathways in NASH. Gastroenterology Publications. https://doi.org/10.1007/s12072-013-9468-6. Retrieved from https://escholarship.umassmed.edu/gastroenterology_pp/134