Futai Lab Student Publications
This collection showcases the journal articles and other publications authored by researchers in the Futai Lab. The Futai Lab at the University of Massachusetts Medical School was established in 2010, in the Brudnick Neuropsychiatric Research Institute, in the Department of Psychiatry. In 2017, the Futai Lab moved to the Department of Neurobiology. Student authors are Wenjie Mao (PhD, Neuroscience Program, 2017), Amy Cheung (MD/PhD Program, 2021), and former students David G. Keener and Sabine Pallat.
Publications from 2021
The Role of Neurexins in Serotonin Signaling and Complex Behaviors, Amy Cheung
Neurexins in serotonergic neurons regulate serotonin transmission and complex mouse behaviors [preprint], Amy Cheung, Aya Matsui, Manabu Abe, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa, and Kensuke Futai
Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction, Motokazu Uchigashima, Amy Cheung, and Kensuke Futai
Publications from 2020
A highly efficient method for single-cell electroporation in mouse organotypic hippocampal slice culture, David G. Keener, Amy Cheung, and Kensuke Futai
A Specific Neuroligin3-αNeurexin1 Code Regulates GABAergic Synaptic Function in Mouse Hippocampus [preprint], Motokazu Uchigashima, Kohtarou Konno, Emily Demchak, Amy Cheung, Takuya Watanabe, David G. Keener, Manabu Abe, Timmy Le, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa, Masahiko Watanabe, and Kensuke Futai
Specific Neuroligin3-alphaNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus, Motokazu Uchigashima, Kohtarou Konno, Emily Demchak, Amy Cheung, Takuya Watanabe, David G. Keener, Manabu Abe, Timmy Le, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa, Masahiko Watanabe, and Kensuke Futai
Neuroligin3 splice isoforms shape inhibitory synaptic function in the mouse hippocampus, Motokazu Uchigashima, Ming Leung, Takuya Watanabe, Amy Cheung, Timmy Le, Sabine Pallat, Alexandre Luis Marques Dinis, Masahiko Watanabe, Yuka Imamura Kawasawa, and Kensuke Futai
Publications from 2019
Differential expression of neurexin genes in the mouse brain, Motokazu Uchigashima, Amy Cheung, Julie Suh, Masahiko Watanabe, and Kensuke Futai
Publications from 2018
Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1, Wenjie Mao, Anna C. Salzberg, Motokazu Uchigashima, Yuto Hasegawa, Hanno Hock, Masahiko Watanabe, Schahram Akbarian, Yuka Imamura. Kawasawa, and Kensuke Futai
Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice, TeChen Tzeng, Yuto Hasegawa, Risa Iguchi, Amy Cheung, Daniel R. Caffrey, Elizabeth Jeanne Thatcher, Wenjie Mao, Gail Germain, Nelsy DePaula Tamburro, Shigeo Okabe, Michael T. Heneka, Eicke Latz, Kensuke Futai, and Douglas T. Golenbock
Publications from 2017
Luciferase shRNA Presents off-Target Effects on Voltage-Gated Ion Channels in Mouse Hippocampal Pyramidal Neurons, Yuto Hasegawa, Wenjie Mao, Sucharita Saha, Georgia Gunner, Jenya Kolpakova, Gilles E. Martin, and Kensuke Futai
Molecular Players in Preserving Excitatory-Inhibitory Balance in the Brain, Wenjie Mao
Publications from 2016
MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations, Md Helal Uddin Biswas, Sandra Almeida, Rodrigo Lopez-Gonzalez, Wenjie Mao, Zhijun Zhang, Anna M. Karydas, Michael D. Geschwind, Jacek Biernat, Eva-Maria Mandelkow, Kensuke Futai, Bruce L. Miller, and Fen-Biao Gao
Publications from 2015
Shank1 regulates excitatory synaptic transmission in mouse hippocampal parvalbumin-expressing inhibitory interneurons, Wenjie Mao, Takuya Watanabe, Sukhee Cho, Jeffrey L. Frost, Tina Truong, Xiaohu Zhao, and Kensuke Futai
Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme, Brian T. Nasipak, Teresita Padilla-Benavides, Karin M. Green, John D. Leszyk, Wenjie Mao, Silvana Konda, Said Sif, Scott A. Shaffer, Yasuyuki Ohkawa, and Anthony N. Imbalzano (Nature communications)
Cognition and mood-related behaviors in l3mbtl1 null mutant mice, Erica Y. Shen, Yan Jiang, Wenjie Mao, Kensuke Futai, Hanno Hock, and Schahram Akbarian
Publications from 2014
Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition, Rahul Bharadwaj, Cyril J. Peter, Yan Jiang, Panos Roussos, Annie Vogel-Ciernia, Erica Y. Shen, Amanda C. Mitchell, Wenjie Mao, Catheryne Whittle, Aslihan Dincer, Mira Jakovcevski, Venu Pothula, Theodore P. Rasmussen, Stella G. Giakoumaki, Panos Bitsios, Ajfar Sherif, Paul D. Gardner, Patricia Ernst, Subroto Ghose, Pamela Sklar, Vahram Haroutunian, Carol Tamminga, Richard H. Myers, Kensuke Futai, Marcelo A. Wood, and Schahram Akbarian
Publications from 2013
Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia, Rahul Bharadwaj, Yan Jiang, Wenjie Mao, Mira Jakovcevski, Aslihan Dincer, Winfried Krueger, Krassimira Garbett, Catheryne Whittle, Jogender S. Tushir, Jia Liu, Adolfo Sequeira, Marquis P. Vawter, Paul D. Gardner, Patrizia Casaccia, Theodore Rasmussen, William E. Bunney Jr., Karoly Mirnics, Kensuke Futai, and Schahram Akbarian