Florman Lab Publications

Title

Shedding light on sperm pHertility

UMMS Affiliation

Department of Cell Biology

Publication Date

2010-02-11

Document Type

Article

Subjects

Animals; Humans; Hydrogen-Ion Concentration; Male; Membrane Potentials; Mice; *Sperm Capacitation; Spermatozoa

Disciplines

Cell Biology

Abstract

The acquisition of fertilization capacity by sperm is regulated by intracellular pH (pH(i)), but the transport pathways that regulate pH(i) are not well understood. Lishko et al. (2010) now report that Hv1, the voltage-sensitive proton channel, is present in human sperm and is an important regulator of the functional maturation of sperm.

DOI of Published Version

10.1016/j.cell.2010.01.035

Source

Cell. 2010 Feb 5;140(3):310-2. Link to article on publisher's site

Journal/Book/Conference Title

Cell

Related Resources

Link to Article in PubMed

PubMed ID

20144756

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