University of Massachusetts Medical School Faculty Publications

 

This collection showcases journal articles, book chapters, and other publications and presentations written by faculty and researchers at the University of Massachusetts Medical School.

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Publications from 2020

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Mycobacterium tuberculosis evasion of Guanylate Binding Protein-mediated host defense in mice requires the ESX1 secretion system [preprint], Andrew J. Olive, Clare M. Smith, Christina E. Baer, Jörn Coers, and Christopher M. Sassetti

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Detecting chromatin interactions along and between sister chromatids with SisterC [preprint], Marlies E. Oomen, Adam K. Hedger, Jonathan K. Watts, and Job Dekker

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An Unusual Case Report of COVID-19 Presenting with Meningitis Symptoms and Shingles, Rebecca Packwood, Gayle Galletta, and Joseph Tennyson

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Regulation of the Mammalian SWI/SNF Family of Chromatin Remodeling Enzymes by Phosphorylation during Myogenesis, Teresita Padilla-Benavides, Pablo Reyes-Gutierrez, and Anthony N. Imbalzano

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Viral Packaging ATPases Utilize a Glutamate Switch to Couple ATPase Activity and DNA Translocation [preprint], Joshua Pajak, Rockney Atz, Brendan J. Hilbert, Marc C. Morais, Brian A. Kelch, and Paul Jardine

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Atomistic Mechanism of Force Generation, Translocation, and Coordination in a Viral Genome Packaging Motor [preprint], Joshua Pajak, Erik Dill, Mark A. White, Brian A. Kelch, Paul Jardine, Gaurav Arya, and Marc C. Morais

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Periprosthetic Tibial Fractures After Total Knee Arthroplasty: Early and Long-Term Clinical Outcomes, Tejbir S. Pannu, Jesus M. Villa, Eric M. Cohen, Roman A. Hayda, Carlos A. Higuera, and Matthew E. Deren

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The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility, Pei-Hsuan Wu, Yu Fu, Katharine Cecchini, Deniz M. Ozata, Amena Arif, Tianxiong Yu, Cansu Colpan, Ildar Gainetdinov, Zhiping Weng, and Phillip D. Zamore

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A meta-analysis of brain DNA methylation across sex, age and Alzheimer’s disease points for accelerated epigenetic aging in neurodegeneration [preprint], C. Pellegrini, Danielle Fernandes Durso, and Maria Giulia Bacalini

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Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice [preprint], Pengpeng Liu, Shun-Qing Liang, Chunwei Zheng, Esther Mintzer, Yan G. Zhao, Karthikeyan Ponnienselvan, Aamir Mir, Erik J. Sontheimer, Guangping Gao, Terence R. Flotte, Scot A. Wolfe, and Wen Xue

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LogoJS: a Javascript package for creating sequence logos and embedding them in web applications, Henry E. Pratt and Zhiping Weng

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An in-depth investigation of the safety and immunogenicity of an inactivated SARS-CoV-2 vaccine [preprint], Jing Pu, Shan Lu, and Qihan Li

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Retrospective Analysis of Emergency Medical Services (EMS) Physician Medical Control Calls, Balaj Rai, Joseph C. Tennyson, and R. Trevor Marshall

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A Comparison of Non-Invasive Blood Pressure Measurement Strategies with Intra-Arterial Measurement, Matthew Rebesco, M. Cornelia Pinkston, Nicholas A. Smyrnios, and Stacy N. Weisberg

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Drug antagonism and single-agent dominance result from differences in death kinetics, Ryan Richards, Hannah R. Schwartz, Megan E. Honeywell, Mariah S. Stewart, Peter Cruz-Gordillo, Anna J. Joyce, Benjamin D. Landry, and Michael J. Lee

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An atlas of cell types in the mammalian epididymis and vas deferens [preprint], Vera D. Rinaldi, Elisa Donnard, Kyle Gellatly, Morten Rasmussen, Alper Kucukural, Onur Yukselen, Manuel Garber, Upasna Sharma, and Oliver J. Rando

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An atlas of cell types in the mouse epididymis and vas deferens, Vera D. Rinaldi, Elisa Donnard, Kyle Gellatly, Morten Rasmussen, Alper Kucukural, Onur Yukselen, Manuel Garber, Upasna Sharma, and Oliver J. Rando

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SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC [preprint], Christian F. Ruiz, Emily D. Montal, John A. Haley, and John D. Haley

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Harmonizing Wearable Biosensor Data Streams to Test Polysubstance Detection, Joshua Rumbut, Hua (Julia) Fang, Honggang Wang, Stephanie Carreiro, David A. Smelson, Brittany Chapman, and Edward Boyer

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Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-Tetrahydrofuran in a Pseudo-Symmetric Dipeptide Isostere, Linah Rusere, Gordon J. Lockbaum, Mina Henes, Sook-Kyung Lee, Ean Spielvogel, Desaboini Nageswara Rao, Klajdi Kosovrasti, Ellen A. Nalivaika, Ronald Swanstrom, Nese Kurt Yilmaz, Celia A. Schiffer, and Akbar Ali

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Salivary metabolite levels in perinatally HIV-infected youth with periodontal disease, Fabian Schulte, Oliver D. King, Bruce J. Paster, Anna-Barbara Moscicki, Tzy-Jyun Yao, Russell B. Van Dyke, Caroline Shiboski, Mark Ryder, George Seage, and Markus Hardt

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PFRED: A computational platform for siRNA and antisense oligonucleotides design [preprint], Simone Sciabola, Hualin Xi, Dario Cruz, Qing Cao, Christine Lawrence, Tianhong Zhang, Sergio Rotstein, Jason D. Hughes, Daniel R. Caffrey, and Robert Stanton

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Containing the Spread of Infectious Disease on College Campuses [preprint], Mirai Shah, Gabrielle Ferra, Susan Fitzgerald, Paul J. Barreira, Pardis C. Sabeti, and Andres Colubri

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SARS-Coronavirus-2 nucleocapsid protein measured in blood using a Simoa ultra-sensitive immunoassay differentiates COVID-19 infection with high clinical sensitivity. [preprint], Dandan Shan, Eicke Latz, and Andrew J. Ball

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UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import [preprint], Tomer Shpilka, Yunguang Du, Qiyuan Yang, Andrew Melber, Nandhitha Uma Naresh, Joshua Lavelle, Pengpeng Liu, Hilla Weidberg, Rui Li, Jun Yu, Lihua Julie Zhu, Lara Strittmatter, and Cole M. Haynes

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FMRP Links Optimal Codons to mRNA stability in Neurons [preprint], Huan Shu, Elisa Donnard, Botao Liu, Ruijia Wang, and Joel D. Richter

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Content and performance of the MiniMUGA genotyping array, a new tool to improve rigor and reproducibility in mouse research [preprint], John Sebastian Sigmon, Christopher M. Sassetti, Clare M. Smith, Martin T. Ferris, Leonard McMillan, and Fernando Pardo-Manuel de Villena

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Efficacy and Safety of Hydroxychloroquine and Chloroquine for COVID-19: A systematic review [preprint], Sonal Singh and Thomas J. Moore

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Beta-cell specific insulin resistance promotes glucose-stimulated insulin hypersecretion [preprint], Søs Skovsø, Hye Lim Noh, Sujin Suk, Brian Gablaski, Jason K. Kim, and James D. Johnson

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Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice [preprint], Clare M. Smith, Richard E. Baker, Megan K. Proulx, Bibhuti B. Mishra, Jarukit E. Long, Michael C. Kiritsy, Michelle Bellerose, Andrew J. Olive, Kenan C. Murphy, Kadamba Papavinasasundaram, Frederick Boehm, Charlotte Reames, and Christopher M. Sassetti

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YAP1 withdrawal in hepatoblastoma drives therapeutic differentiation of tumor cells to functional hepatocyte-like cells, Jordan L. Smith, Tomas Rodriguez, Haiwei Mou, Suet-Yan Kwan, Henry E. Pratt, Xiao-Ou Zhang, Yueying Cao, Shun-Qing Liang, Deniz M. Ozata, Tianxiong Yu, Qiangzong Yin, Max Hazeltine, Zhiping Weng, Erik J. Sontheimer, and Wen Xue

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Nuclear hubs built on RNAs and clustered organization of the genome, Kelly P. Smith, Lisa L. Hall, and Jeanne B. Lawrence

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Resilience and CVD-protective Health Behaviors in Older Women: Examining Racial and Ethnic Differences in a Cross-Sectional Analysis of the Women's Health Initiative, Sparkle Springfield, FeiFei Qin, Haley Hedlin, Charles B. Eaton, Milagros C. Rosal, Herman Taylor, Ursula M. Staudinger, and Marcia L. Stefanick

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ATF-4 and hydrogen sulfide signalling mediate longevity from inhibition of translation or mTORC1 [preprint], Cyril Statzer, Pengpeng Liu, Cole M. Haynes, T. Keith Blackwell, and Collin Y. Ewald

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Recommended Process Outcome Measures for Stop the Bleed Education Programs, Kandra Strauss-Riggs, Thomas D. Kirsch, Erik Prytz, Richard C. Hunt, Carl-Oscar Jonson, Jon Krohmer, Ira Nemeth, and Craig Goolsby

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Clinical Practice Guidelines on Ordering Echocardiography Before Hip Fracture Repair Perform Differently from One Another, Eric F. Swart, Chris Adair, Rachel B. Seymour, and Madhav A. Karunakar

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Modern treatment of tibial shaft fractures: Is there a role today for closed treatment, Eric F. Swart, Chad Lasceski, Luke D. Latario, Jacob Jo, and Uyen-Sa D.T. Nguyen

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Midbrain circuits of novelty processing, Andrew R. Tapper and Susanna Molas Casacuberta

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Chromosome-level assembly of the Atlantic silverside genome reveals extreme levels of sequence diversity and structural genetic variation [preprint], Anna Tigano, Cornell University, Aryn P. Wilder, Ankita Nand, Ye Zhan, Job Dekker, and Nina O. Therkildsen

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Chromosome-level assembly of the Atlantic silverside genome reveals extreme levels of sequence diversity and structural genetic variation [preprint], Anna Tigano, Arne Jacobs, Aryn P. Wilder, Ankita Nand, Ye Zhan, and Job Dekker

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Molecular and Structural Mechanism of Pan-Genotypic HCV NS3/4A Protease Inhibition by Glecaprevir, Jennifer Timm, Klajdi Kosovrasti, Mina Henes, Florian Leidner, Shurong Hou, Akbar Ali, Nese Kurt Yilmaz, and Celia A. Schiffer

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Age, Multiple Chronic Conditions, and COVID-19: A literature review, Mayra Tisminetzky, Christopher Delude, Tara Hebert, Catherine W. Carr, Robert J. Goldberg, and Jerry H. Gurwitz

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Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations, William D. Todd, Anne Venner, Christelle Anaclet, Rebecca Y. Broadhurst, Roberto De Luca, Sathyajit S. Bandaru, Lindsay Issokson, Lauren M. Hablitz, Olga Cravetchi, Elda Arrigoni, John N. Campbell, Charles N. Allen, David P. Olson, and Patrick M. Fuller

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Mobile health assessments of geriatric elements in older patients with atrial fibrillation: The Mobile SAGE-AF Study (M-SAGE), Katherine Trymbulak, Eric Y. Ding, Francesca Marino, and Zi-Yue Wang

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CRISPR-enhanced human adipocyte 'browning' as cell therapy for metabolic disease [preprint], Emmanouela Tsagkaraki, Sarah M. Nicoloro, Tiffany DeSouza, Javier Solivan-Rivera, Anand Desai, Yuefei Shen, Mark Kelly, Adilson L. Guilherme, Felipe Henriques, Raed Ibraheim, Nadia Amrani, Kevin Luk, Stacy Maitland, Randall H. Friedline, Lauren Tauer, Xiaodi Hu, Jason K. Kim, Scot A. Wolfe, Erik J. Sontheimer, Silvia Corvera, and Michael P. Czech

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High-resolution analysis of differential gene expression during skeletal muscle atrophy and programmed cell death, Junko Tsuji, Travis Thomson, Elizabeth Chan, Christine K. Brown, Julia Oppenheimer, Carol Bigelow, Xianjun Dong, William E. Theurkauf, Zhiping Weng, and Lawrence M. Schwartz

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A Specific Neuroligin3-αNeurexin1 Code Regulates GABAergic Synaptic Function in Mouse Hippocampus [preprint], Motokazu Uchigashima, Kohtarou Konno, Emily Demchak, Amy Cheung, Takuya Watanabe, David G. Keener, Manabu Abe, Timmy Le, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa, Masahiko Watanabe, and Kensuke Futai

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Specific Neuroligin3-alphaNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus, Motokazu Uchigashima, Kohtarou Konno, Emily Demchak, Amy Cheung, Takuya Watanabe, David G. Keener, Manabu Abe, Timmy Le, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa, Masahiko Watanabe, and Kensuke Futai

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Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors: US Preventive Services Task Force Recommendation Statement, US Preventive Services Task Force, Alex H. Krist, and Lori Pbert

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Screening for Hepatitis B Virus Infection in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement, US Preventive Services Task Force, Alex H. Krist, and Lori Pbert

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Screening for High Blood Pressure in Children and Adolescents: US Preventive Services Task Force Recommendation Statement, US Preventive Services Task Force, Alex H. Krist, and Lori Pbert

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Primary Care Interventions for Prevention and Cessation of Tobacco Use in Children and Adolescents: US Preventive Services Task Force Recommendation Statement, US Preventive Services Task Force, Douglas K. Owens, and Lori Pbert

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Screening for Bacterial Vaginosis in Pregnant Persons to Prevent Preterm Delivery: US Preventive Services Task Force Recommendation Statement, US Preventive Services Task Force, Douglas K. Owens, and Lori Pbert

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Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoter [preprint], E. van der Kouwe, Lucio H. Castilla, D. G. Tenen, and P. B. Staber

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High-Resolution Mapping of Multiway Enhancer-Promoter Interactions Regulating Pathogen Detection, Pranitha Vangala, Rachel Murphy, Sofia A. Quinodoz, Kyle J. Gellatly, Patrick E. McDonel, Mitchell Guttman, and Manuel Garber

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The Incidence of Node-Positive Non-small-Cell Lung Cancer Undergoing Sublobar Resection and the Role of Radiation in Its Management, John M. Varlotto, Isabel Cristina Martins Emmerick, Debra Maddox, Christine Herbert, Molly Griffin, Paul Rava, Thomas J. Fitzgerald, Paulo Oliveira, Jennifer Baima, Rahul N. Sood, William Walsh, Lacey J. McIntosh, Feiran Lou, and Mark W. Maxfield

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ZNF410 represses fetal globin by devoted control of CHD4/NuRD [preprint], Divya S. Vinjamur, Qiuming Yao, Mitchel A. Cole, Connor McGuckin, Chunyan Ren, Jing Zeng, Mir Hossain, Kevin Luk, Scot A. Wolfe, Luca Pinello, and Daniel E. Bauer

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WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization [preprint], Melissa D. Walker, Gabrielle E. Giese, Amy D. Holdorf, Sushila Bhattacharya, Cedric Diot, Aurian Garcia-Gonzalez, Brent Horowitz, Yong-Uk Lee, Thomas Leland, Xuhang Li, Zeynep Mirza, Huimin Na, Shivani Nanda, Olga Ponomarova, Hefei Zhang, Jingyan Zhang, L. Safak Yilmaz, and Albertha J. M. Walhout

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Genome-Wide Mapping of Human DNA Replication by Optical Replication Mapping Supports a Stochastic Model of Eukaryotic Replication Timing [preprint], Weitao Wang, Kyle Klein, Karel Proesmans, Northwestern University, Claire Marchal, Xiaopeng Zhu, Tyler M. Borrman, Alex Hastie, Zhiping Weng, Simon Fraser University, Paris Sciences et Lettres University, Florida State University, and Nicholas R. Rhind

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Flexible motor sequence generation during stereotyped escape responses, Yuan Wang, Xiaoqian Zhang, Qi Xin, Wesley Hung, Jeremy Florman, Jing Huo, Tianqi Xu, Yu Xie, Mark J. Alkema, Mei Zhen, and Quan Wen

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DGAT1 is a lipid metabolism oncoprotein that enables cancer cells to accumulate fatty acid while avoiding lipotoxicity [preprint], Daniel J. Wilcock, Melissa Kasheta, and Craig J. Ceol

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TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca(2), Brian M. Woolums, Kendra Takle, and Yang Xiang

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Inhibition of PAD2 Improves Survival in a Mouse Model of Lethal LPS-Induced Endotoxic Shock, Zhenyu Wu, Qiufang Deng, Baihong Pan, Hasan B. Alam, Yuzi Tian, Umar F. Bhatti, Baoling Liu, Santanu Mondal, Paul R. Thompson, and Yongqing Li

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Alveolar size effects on nanoparticle deposition in rhythmically expanding-contracting terminal alveolar models, Jinxiang Xi, Mohamed Talaat, Xiuhua April Si, Pan Han, Haibo Dong, and Shaokuan Zheng

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Serological Analysis Reveals an Imbalanced IgG Subclass Composition Associated with COVID-19 Disease Severity [preprint], Jennifer L. Yates, Ejemel Monir, Qi Li, Yan Wang, and William T. Lee

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Implantation and Gastrulation Abnormalities Characterize Early Embryonic Lethal Mouse Lines [preprint], Yeonsoo Yoon, Joy Riley, Judith Gallant, Ping Xu, and Jaime A. Rivera-Pérez

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Multiple Joint Osteonecrosis in a Patient on Long-term Intranasal Corticosteroids, Mohamed A. Yousef and David C. Ayers

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Clinical evaluation of three respiratory gating schemes for different respiratory patterns on cardiac SPECT, Duo Zhang, Jingzhang Sun, P. Hendrik Pretorius, Michael A. King, and Greta S. P. Mok

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Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity, Xuming Zhou, Elinor K. Karlsson, and Vadim N. Gladyshev

Publications from 2019

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A chromosome folding intermediate at the condensin-to-cohesin transition during telophase [preprint], Kristin Abramo, Anne-Laure Valton, Sergey V. Venev, Hakan Ozadam, A. Nicole Fox, and Job Dekker

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Regulatory asymmetry in the negative single-input module network motif: Role of network size, growth rate and binding affinity [preprint], Zulfikar Ali, Vinuselvi Parisutham, Sandeep Choubey, and Robert C. Brewster

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Which Chart Elements Accurately Identify Emergency Department Visits for Suicidal Ideation or Behavior, Sarah A. Arias, Edwin D. Boudreaux, Elizabeth Chen, Ivan Miller, Carlos A. Camargo Jr., Richard N. Jones, and Lisa Uebelacker

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Progressive alignment with Cactus: a multiple-genome aligner for the thousand-genome era [preprint], Joel Armstrong, Elinor K. Karlsson, and Benedict Paten

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Tumor cell-organized fibronectin is required to maintain a dormant breast cancer population [preprint], Lauren E. Barney, Christopher L. Hall, Alyssa D. Schwartz, Akia N. Parks, Christopher Sparages, Sualyneth Galarza, Manu O. Platt, Arthur M. Mercurio, and Shelly R. Peyton

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VERB: VFCDM-Based Electrocardiogram Reconstruction and Beat Detection Algorithm, Syed Khairul Bashar, Allan J. Walkey, David D. McManus, and Ki H. Chon

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Distinct features of nucleolus-associated domains in mouse embryonic stem cells [preprint], Aizhan Bizhanova, Aimin Yan, Jun Yu, Lihua Julie Zhu, and Paul D. Kaufman

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Constrained mutational sampling of amino acids in HIV-1 protease evolution, Jeffrey I. Boucher, Troy W. Whitfield, Ann Dauphin, Gily S. Nachum, Carl Hollins III, Konstantin B. Zeldovich, Ronald Swanstrom, Celia A. Schiffer, Jeremy Luban, and Daniel N. Bolon

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HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation [preprint], Laure Bridoux, Peyman Zarrineh, Joshua Mallen, Mike Phuycharoen, Victor Latorre, Frank Ladam, Marta Losa, Charles G. Sagerstrom, Kimberley A. Mace, Magnus Rattray, and Nicoletta Bobola

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Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis, Laura Cau, Hidenari Takahara, Paul R. Thompson, Guy Serre, Marie-Claire Mechin, and Michel Simon

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A big-data approach to understanding metabolic rate and response to obesity in laboratory mice [preprint], June K. Corrigan, Deepti Ramachandran, Yuchen He, Colin Palmer, Michael J. Jurczak, Bingshan Li, Randall H. Friedline, Jason K. Kim, Jon J. Ramsey, Louise Lantier, Owen P. McGuinness, Alexander S. Banks, and Mouse Metabolic Phenotyping Center Energy Balance Working Group

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The adaptive potential of the M-domain of yeast Hsp90 [preprint], Pamela A. Cote-Hammarlof, Inês Fragata, Julia M. Flynn, Konstantin B. Zeldovich, Claudia Bank, and Daniel N. Bolon

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A minimal CRISPR-Cas3 system for genome engineering [preprint], Bálint Csörgő, Lina M. León, Ilea J. Chau-Ly, Alejandro Vasquez-Rifo, Joel D. Berry, Caroline Mahendra, Emily D. Crawford, Jennifer D. Lewis, and Joseph Bondy-Denomy

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MED20 is essential for early embryogenesis and regulates NANOG expression, Wei Cui, Chelsea Marcho, Yongsheng Wang, Rinat Degani, Morgane Golan, Kimberly D. Tremblay, Jaime A. Rivera-Pérez, and Jesse Mager

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Influence of different glycoproteins and of the virion core on SERINC5 antiviral activity [preprint], William E. Diehl, Mehmet Hakan Guney, Pyae Phyo Kyawe, Judith M. White, Massimo Pizzato, and Jeremy Luban

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Investigating the influence of environment on the evolution of Hsp90 using comprehensive fitness maps [preprint], Julia M. Flynn, Ammeret Rossouw, Pamela A. Cote-Hammarlof, Ines Fragata, David Mavor, Carl Hollins III, Claudia Bank, and Daniel N. Bolon

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Higher order genomic organization and epigenetic control maintain cellular identity and prevent breast cancer, A. J. Fritz, Jeffrey A. Nickerson, Anthony N. Imbalzano, and Gary S. Stein

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A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry [preprint], Janelle A. Hayes, Brendan J. Hilbert, Christl Gaubitz, Nicholas P. Stone, and Brian A. Kelch

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Interplay between axonal Wnt5-Vang and dendritic Wnt5-Drl/Ryk signaling controls glomerular patterning in the Drosophila antennal lobe [preprint], Huey Hing, Noah Reger, Jennifer Snyder, and Lee G. Fradkin

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WormCat: an online tool for annotation and visualization of Caenorhabditis elegans genome-scale data [preprint], Amy D. Holdorf, Daniel P. Higgins, Anne C. Hart, Peter R. Boag, Gregory J. Pazour, Albertha J. M. Walhout, and Amy K. Walker

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RUNX1-dependent mechanisms in biological control and dysregulation in cancer, Deli Hong, Andrew J. Fritz, Jonathan A. Gordon, Coralee E. Tye, Joseph R. Boyd, Kirsten M. Tracy, Seth E. Frietze, Frances E. Carr, Jeffrey A. Nickerson, Andre J. Van Wijnen, Anthony N. Imbalzano, Sayyed K. Zaidi, Jane B. Lian, Janet L. Stein, and Gary S. Stein

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Pathognomonic and epistatic genetic alterations in B-cell non-Hodgkin lymphoma [preprint], Man Chun John Ma, Benjamin J. Chen, and Michael R. Green

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Mutations in the SPTLC1 gene are a cause of amyotrophic lateral sclerosis that may be amenable to serine supplementation [preprint], Janel O. Johnson, Ruth Chia, Robert H. Brown Jr., and John E. Landers

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A DNA-guided Argonaute Protein Functions in DNA Replication in Thermus thermophilus [preprint], Samson M. Jolly, Ildar Gainetdinov, , Han Zhang, Lara Strittmatter, Gregory M. Hendricks, Avantika Dhabaria, Beatrix Ueberheide, and Phillip D. Zamore

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Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis, Shashi Kant, Siobhan M. Craige, Kai Chen, Michaella M. Reif, Heather Learnard, Mark Kelly, Amada D. Caliz, Khanh-Van T. Tran, Kasmir Ramo, Owen M. Peters, Marc R. Freeman, Roger J. Davis, and John F. Keaney Jr.

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Epstein Barr virus genomes reveal population structure and type 1 association with endemic Burkitt lymphoma [preprint], Yasin Kaymaz, Cliff Oduor, Ozkan Aydemir, Micah Luftig, Juliana Otieno, John Michael Ong'echa, Jeffrey A. Bailey, and Ann M. Moormann

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Evidence that APP gene copy number changes reflect recombinant vector contamination [preprint], Junho Kim, Boxun Zhao, August Yue Huang, Michael B. Miller, Michael A. Lodato, Christopher A. Walsh, and Eunjung Alice Lee

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Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved AS-NMD pathways [preprint], Carrie Kovalak, Mihir Metkar, and Melissa J. Moore

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Ste5 Membrane Localization Allows MAPK Pathway Signaling in trans Between Kinases on Separate Scaffold Molecules [preprint], Rachel E. Lamson, Matthew J. Winters, and Peter M. Pryciak

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Chitosan biosynthesis and virulence in the human fungal pathogen Cryptococcus gattii [preprint], Woei C. Lam, Rajendra Upadhya, Charles A. Specht, Abigail E. Ragsdale, Camaron R. Hole, Stuart M. Levitz, and Jennifer K. Lodge

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Tissue-specific Genome Editing in vivo by MicroRNA-repressible Anti-CRISPR Proteins [preprint], Jooyoung Lee, Haiwei Mou, Raed Ibraheim, Shun-Qing Liang, Wen Xue, and Erik J. Sontheimer