Department of Neurobiology; Freeman Lab
Animals; Drosophila; Humans; Neural Stem Cells; Neurogenesis; Neuroglia; Neurons; Synapses
Cell Biology | Molecular and Cellular Neuroscience
Glia serve many important functions in the mature nervous system. In addition, these diverse cells have emerged as essential participants in nearly all aspects of neural development. Improved techniques to study neurons in the absence of glia, and to visualize and manipulate glia in vivo, have greatly expanded our knowledge of glial biology and neuron-glia interactions during development. Exciting studies in the last decade have begun to identify the cellular and molecular mechanisms by which glia exert control over neuronal circuit formation. Recent findings illustrate the importance of glial cells in shaping the nervous system by controlling the number and connectivity of neurons.
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© 2013 Corty and Freeman This article is distributed under the terms of an Attribution– Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
DOI of Published Version
J Cell Biol. 2013 Nov 11;203(3):395-405. doi: 10.1083/jcb.201306099. Link to article on publisher's site
The Journal of cell biology
Corty, Megan M. and Freeman, Marc R., "Cell biology in neuroscience: Architects in neural circuit design: glia control neuron numbers and connectivity" (2013). University of Massachusetts Medical School Faculty Publications. 807.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 License.