University of Massachusetts Medical School Faculty Publications
UMMS Affiliation
Department of Neurobiology; Freeman Lab
Publication Date
2013-11-11
Document Type
Article
Subjects
Animals; Drosophila; Humans; Neural Stem Cells; Neurogenesis; Neuroglia; Neurons; Synapses
Disciplines
Cell Biology | Molecular and Cellular Neuroscience
Abstract
Glia serve many important functions in the mature nervous system. In addition, these diverse cells have emerged as essential participants in nearly all aspects of neural development. Improved techniques to study neurons in the absence of glia, and to visualize and manipulate glia in vivo, have greatly expanded our knowledge of glial biology and neuron-glia interactions during development. Exciting studies in the last decade have begun to identify the cellular and molecular mechanisms by which glia exert control over neuronal circuit formation. Recent findings illustrate the importance of glial cells in shaping the nervous system by controlling the number and connectivity of neurons.
Rights and Permissions
© 2013 Corty and Freeman This article is distributed under the terms of an Attribution– Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
DOI of Published Version
10.1083/jcb.201306099
Source
J Cell Biol. 2013 Nov 11;203(3):395-405. doi: 10.1083/jcb.201306099. Link to article on publisher's site
Related Resources
Journal/Book/Conference Title
The Journal of cell biology
PubMed ID
24217617
Repository Citation
Corty, Megan M. and Freeman, Marc R., "Cell biology in neuroscience: Architects in neural circuit design: glia control neuron numbers and connectivity" (2013). University of Massachusetts Medical School Faculty Publications. 807.
https://escholarship.umassmed.edu/faculty_pubs/807
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 License.