University of Massachusetts Medical School Faculty Publications

UMMS Affiliation

Department of Neurobiology; Freeman Lab

Publication Date

2013-11-11

Document Type

Article

Subjects

Animals; Drosophila; Humans; Neural Stem Cells; Neurogenesis; Neuroglia; Neurons; Synapses

Disciplines

Cell Biology | Molecular and Cellular Neuroscience

Abstract

Glia serve many important functions in the mature nervous system. In addition, these diverse cells have emerged as essential participants in nearly all aspects of neural development. Improved techniques to study neurons in the absence of glia, and to visualize and manipulate glia in vivo, have greatly expanded our knowledge of glial biology and neuron-glia interactions during development. Exciting studies in the last decade have begun to identify the cellular and molecular mechanisms by which glia exert control over neuronal circuit formation. Recent findings illustrate the importance of glial cells in shaping the nervous system by controlling the number and connectivity of neurons.

Rights and Permissions

© 2013 Corty and Freeman This article is distributed under the terms of an Attribution– Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

DOI of Published Version

10.1083/jcb.201306099

Source

J Cell Biol. 2013 Nov 11;203(3):395-405. doi: 10.1083/jcb.201306099. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Journal/Book/Conference Title

The Journal of cell biology

PubMed ID

24217617

Creative Commons License

Creative Commons Attribution-Noncommercial-Share Alike 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 License.

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