Assessing health-related quality of life in patients with benign non-toxic goitre
Department of Quantitative Health Sciences
Goiter; *Health Status; Humans; *Quality of Life; *Questionnaires; Reproducibility of Results; Self Report; Treatment Outcome
Diseases | Endocrine System Diseases | Endocrinology, Diabetes, and Metabolism | Health Services Research
Health-related quality of life (HRQoL) assessments are increasingly used to evaluate treatment effects and to shape the delivery of value based care. Valid generic and disease specific tools are available for quantifying HRQoL in patients with non-toxic goitre. However, few studies have applied these validated instruments to assess HRQoL in patients with benign non-toxic goitre. Limited evidence suggests that patients with non-toxic goitre have HRQoL impairments in multiple HRQoL domains. While the HRQoL-impact of non-toxic goitre may be small relative to other severely disabling medical conditions, treatment is almost exclusively elected for HRQoL indications. Thus better quantification of HRQoL, particularly at better (or more favorable) levels where many patients score, is essential. Web and mobile technologies have eased the ability to deliver surveys to patients. Routine consideration of HRQoL provides the opportunity to monitor the impact of treatment on the outcomes most meaningful for patients and the opportunity to help shape the delivery of value based health care.
DOI of Published Version
Best Pract Res Clin Endocrinol Metab. 2014 Aug;28(4):559-75. doi: 10.1016/j.beem.2014.01.009. Epub 2014 Jan 28. Link to article on publisher's site
Best practice and research. Clinical endocrinology and metabolism
Watt, Torquil; Cramon, Per; Frendl, Daniel M.; and Ware, John E. Jr., "Assessing health-related quality of life in patients with benign non-toxic goitre" (2014). University of Massachusetts Medical School Faculty Publications. 732.