UMass Chan Medical School Faculty Publications
Title
Malignancy and acute pulmonary embolism: risk stratification including the right to left ventricle diameter ratio in 1596 subjects
UMMS Affiliation
Department of Radiology
Publication Date
2013-5
Document Type
Article
Subjects
Pulmonary Embolism; Neoplasms
Disciplines
Cardiovascular Diseases | Neoplasms | Oncology | Radiology | Respiratory Tract Diseases
Abstract
PURPOSE: To test the hypothesis that subjects with a known malignancy at the time of acute pulmonary embolism (PE) have different clinical characteristics and predictors of 30-day all-cause mortality when compared with subjects with no known malignancy.
MATERIALS AND METHODS: A retrospective (August 2003 to March 2010) cohort of 1596 consecutive positive (for acute PE) computed tomography pulmonary angiograms (CTPAs) performed at a single, large, urban teaching hospital was separated into those from subjects with (n=835) and those from subjects without (n=761) a known malignancy. Clinical characteristics were compared between groups, and a logistic regression model determined predictors of 30-day all-cause mortality for each group.
RESULTS: Subjects with malignancy were older (60.8+/-13.9 vs. 54.5+/-18.8 y, P1.0) had a higher risk of 30-day death only among subjects with no known malignancy at the time of the CTPA (odds ratio=4.08, 95% confidence interval: 1.67-9.96).
CONCLUSIONS: Among subjects who present with acute PE, those with a malignancy had different clinical characteristics and predictors of mortality when compared with the cohort of subjects with no known malignancy. A computed tomography-derived right to left ventricular diameter ratio predicts 30-day all-cause mortality only for those subjects who do not have a malignancy.
DOI of Published Version
10.1097/RTI.0b013e3182870bf9
Source
J Thorac Imaging. 2013 May;28(3):196-201. doi: 10.1097/RTI.0b013e3182870bf9. Link to article on publisher's site
Related Resources
Journal/Book/Conference Title
Journal of thoracic imaging
PubMed ID
23478511
Repository Citation
Cai B, Bedayat A, George E, Hunsaker AR, Dill KE, Rybicki FJ, Kumamaru KK. (2013). Malignancy and acute pulmonary embolism: risk stratification including the right to left ventricle diameter ratio in 1596 subjects. UMass Chan Medical School Faculty Publications. https://doi.org/10.1097/RTI.0b013e3182870bf9. Retrieved from https://escholarship.umassmed.edu/faculty_pubs/57