A pilot study of prehospital antibiotics for severe sepsis
Department of Emergency Medicine
Bacterial Infections and Mycoses | Emergency Medicine
The primary aim of our investigation was to describe the safety and feasibility of a protocol for prehospital recognition of sepsis with hypotension and septic shock, drawing of blood cultures, and administration of intravenous (IV) antibiotics in an urban EMS service, thereby adding to the limited U.S. literature available on this subject and supporting the development of a large-scale randomized control trial (RCT). Primary feasibility measures included the frequency of allergic reactions, culture contamination, and paramedic adherence to the protocol in the prehospital environment.
DOI of Published Version
Cunningham CT, Sanseverino A, Reznek M, Borges E, Beth Urhoy M, Gross K, Broach JP, O'Connor L. A pilot study of prehospital antibiotics for severe sepsis. Acad Emerg Med. 2021 Sep 4. doi: 10.1111/acem.14388. Epub ahead of print. PMID: 34480817. Link to article on publisher's site
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
Cunningham CT, Sanseverino A, Reznek MA, Borges E, Beth Urhoy M, Gross K, Broach J, O'Connor L. (2021). A pilot study of prehospital antibiotics for severe sepsis. UMass Chan Medical School Faculty Publications. https://doi.org/10.1111/acem.14388. Retrieved from https://escholarship.umassmed.edu/faculty_pubs/2107