University of Massachusetts Medical School Faculty Publications

Title

Gaining Insight into Vitiligo Genetics through the Lens of a Large Epidemiologic Study

UMMS Affiliation

Department of Dermatology; Program in Bioinformatics and Integrative Biology; Program in Molecular Medicine; Garber Lab

Publication Date

2021-04-01

Document Type

Article

Disciplines

Dermatology | Epidemiology | Genetics and Genomics | Skin and Connective Tissue Diseases

Abstract

Several epidemiologic studies and GWASs have implicated genetic factors in the pathogenesis of vitiligo. The report by Kim et al. (2020) describes a prospective cohort study from Korea that has the greatest statistical power to date in addressing the epidemiology of vitiligo inheritance. The authors reported the incidence risk ratios in individuals whose first-degree relatives or spouses are affected, providing clear evidence that both genetic and nongenetic factors influence the pathogenesis of vitiligo.

DOI of Published Version

10.1016/j.jid.2020.10.005

Source

Okamura K, Garber M, Harris JE. Gaining Insight into Vitiligo Genetics through the Lens of a Large Epidemiologic Study. J Invest Dermatol. 2021 Apr;141(4):718-721. doi: 10.1016/j.jid.2020.10.005. PMID: 33752810. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Journal/Book/Conference Title

The Journal of investigative dermatology

PubMed ID

33752810

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