University of Massachusetts Medical School Faculty Publications
Title
Location-known-exactly human-observer ROC studies of attenuation and other corrections for SPECT lung imaging
UMMS Affiliation
Division of Nuclear Medicine, Department of Radiology
Publication Date
2006-10-29
Document Type
Conference Proceeding
Disciplines
Analytical, Diagnostic and Therapeutic Techniques and Equipment | Bioimaging and Biomedical Optics | Biological and Chemical Physics | Nuclear | Nuclear Engineering | Radiology
Abstract
We use receiver operating characteristic (ROC) analysis of a location-known-exactly (LKE) lesion detection task to compare the image quality of SPECT reconstruction with and without various combinations of attenuation correction (AC), scatter correction (SC) and resolution compensation (RC). Hybrid images were generated from Tc-99m labelled NeoTect clinical backgrounds into which Monte Carlo simulated solitary pulmonary nodule (SPN) lung lesions were added, then reconstructed using several strategies. Results from a human-observer study show that attenuation correction degrades SPN detection, while resolution correction improves SPN detection, even when the lesion location is known. This agrees with the results of a previous localization-response operating characteristic (LROC) study using the same images, indicating that location uncertainty is not the sole source of the changes in detection accuracy.
Keywords
SPECT, lung imaging, attenuation correction, lesion detection, ROC and LROC analysis
DOI of Published Version
10.1109/NSSMIC.2006.353696
Source
Lehovich A, Gifford HC, King MA. Location-known-exactly human-observer ROC studies of attenuation and other corrections for SPECT lung imaging. IEEE Nucl Sci Symp Conf Rec (1997). 2006;6:3229-3232. doi: 10.1109/NSSMIC.2006.353696. PMID: 19194523; PMCID: PMC2633939. Link to article on publisher's site
Related Resources
Journal/Book/Conference Title
IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium
PubMed ID
19194523
Repository Citation
Lehovich A, Gifford HC, King MA. (2006). Location-known-exactly human-observer ROC studies of attenuation and other corrections for SPECT lung imaging. University of Massachusetts Medical School Faculty Publications. https://doi.org/10.1109/NSSMIC.2006.353696. Retrieved from https://escholarship.umassmed.edu/faculty_pubs/1757