University of Massachusetts Medical School Faculty Publications
Title
Impact of Mismatched Detector-Blur Models on Ga SPECT Tumor Detection
UMMS Affiliation
Department of Radiology
Publication Date
2007-10-26
Document Type
Conference Proceeding
Disciplines
Analytical, Diagnostic and Therapeutic Techniques and Equipment | Bioimaging and Biomedical Optics | Biological and Chemical Physics | Nuclear | Nuclear Engineering | Radiology
Abstract
The quality of SPECT images suffers from the effects of photon attenuation and scatter, and from distance-dependent collimator blur, and many researchers have shown the benefit of compensating for these degradations in the inverse problem. For this work, we examined how using an incorrect collimator-blur model affects the detection and localization of (67)Ga-avid lymphomas in simulated chest scans. In particular, we considered whether blur-overcompensation can enhance reconstructed images for purposes of localizing tumors. Variations in the correct linear model for medium-energy, parallel-hole collimators were compared by means of LROC studies with human and localizing model observers. Imaging data consisted of Simind projections of the MCAT phantom, and RBI reconstructions were performed. Our results indicate that tumor-detection performance is not improved by using a mismatched RC model. Reconstruction with increased RC requires more iterations, which leads to longer noise correlations. Our results also suggest a substantial observer insensitivity to the accuracy of the RC model.
Keywords
Image reconstruction, Single photon emission computed tomography, Attenuation, Electromagnetic scattering, Particle scattering, Optical collimators, Degradation, Inverse problems, Neoplasms, Humans
DOI of Published Version
10.1109/NSSMIC.2007.4437050
Source
Gifford HC, King MA. Impact of Mismatched Detector-Blur Models on Ga SPECT Tumor Detection. IEEE Nucl Sci Symp Conf Rec (1997). 2007;6:4226-4229. doi: 10.1109/NSSMIC.2007.4437050. PMID: 19890463; PMCID: PMC2772205. Link to article on publisher's site
Related Resources
Journal/Book/Conference Title
IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium
PubMed ID
19890463
Repository Citation
Gifford HC, King MA. (2007). Impact of Mismatched Detector-Blur Models on Ga SPECT Tumor Detection. University of Massachusetts Medical School Faculty Publications. https://doi.org/10.1109/NSSMIC.2007.4437050. Retrieved from https://escholarship.umassmed.edu/faculty_pubs/1753