University of Massachusetts Medical School Faculty Publications
Title
A point process model of respiratory dynamics in early physiological development
UMMS Affiliation
Department of Neurology
Publication Date
2011-08-30
Document Type
Article
Disciplines
Biomedical Engineering and Bioengineering | Circulatory and Respiratory Physiology | Medical Physiology | Neurology | Physiological Processes | Respiratory System
Abstract
Interbreath interval (IBI), the time interval between breaths, and its variations in time around the mean, the IBI variability, are important measures associated with irregularity of breathing. The IBI histogram generally follows a power law distribution with its characterizing parameters changing with maturation. To assess the dynamics of breathing we propose a point process model of IBI with a lognormal parametric structure to appropriately represent the stochastic nature of the IBI distribution. We estimate the time varying evolution of the characterizing parameters to represent the dynamic nature of breathing, and thereby provide a time-varying measure of irregularity in breathing. The reliability of the model to capture the data is assessed using Kolmogorov-Smirnov (KS) and independence tests. Our results validate the novel approach in the assessment of the irregularity of breathing by analyzing respiratory recordings from newborn rats and preterm infants.
Keywords
interbreath interval, breathing dynamics, irregularity, neurophysiology
DOI of Published Version
10.1109/IEMBS.2011.6090771
Source
Indic P, Paydarfar D, Barbieri R. A point process model of respiratory dynamics in early physiological development. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:3804-7. doi: 10.1109/IEMBS.2011.6090771. PMID: 22255168; PMCID: PMC3340562. Link to article on publisher's site
Related Resources
Journal/Book/Conference Title
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
PubMed ID
22255168
Repository Citation
Indic P, Paydarfar D, Barbieri R. (2011). A point process model of respiratory dynamics in early physiological development. University of Massachusetts Medical School Faculty Publications. https://doi.org/10.1109/IEMBS.2011.6090771. Retrieved from https://escholarship.umassmed.edu/faculty_pubs/1750