Acute kidney injury due to intravenous bleach injection
Department of Emergency Medicine; Department of Pathology; Division of Renal Medicine
Acute Kidney Injury; Sodium Hypochlorite
Emergency Medicine | Female Urogenital Diseases and Pregnancy Complications | Male Urogenital Diseases | Medical Toxicology | Nephrology | Pathology
INTRODUCTION: Sodium hypochlorite is the active ingredient in bleach, a ubiquitous household disinfectant, and has known toxicities depending on route of exposure and amount. Acute kidney injury due to sodium hypochlorite exposure has never been reported. Patients that did develop nephrotoxicity following bleach exposure did so due to development of other risk factors for kidney injury such as volume depletion or sepsis.
DISCUSSION: We report a patient who presented with black urine after parenteral self-administration of a large quantity of bleach. We review the clinical presentation, laboratory and biopsy findings, and outcome as well as discuss possible mechanisms of sodium hypochlorite toxicity and management strategies.
DOI of Published Version
J Med Toxicol. 2013 Mar;9(1):71-4. doi: 10.1007/s13181-012-0259-6. Link to article on publisher's site
Journal of medical toxicology : official journal of the American College of Medical Toxicology
Ashish, Verma; Vanguri, Vijay; Golla, Venkata; Rhyee, Sean Hyun; Trainor, Matthew; and Konstantin, Abramov, "Acute kidney injury due to intravenous bleach injection" (2013). University of Massachusetts Medical School Faculty Publications. 165.