Making fair comparisons in pregnancy medication safety studies: An overview of advanced methods for confounding control
Department of Quantitative Health Sciences
Maternal and Child Health | Pharmaceutical Preparations | Women's Health
Understanding the safety of medication use during pregnancy relies on observational studies: However, confounding in observational studies poses a threat to the validity of estimates obtained from observational data. Newer methods, such as marginal structural models and propensity calibration, have emerged to deal with complex confounding problems, but these methods have seen limited uptake in the pregnancy medication literature. In this article, we provide an overview of newer advanced methods for confounding control and show how these methods are relevant for pregnancy medication safety studies.
DOI of Published Version
Pharmacoepidemiol Drug Saf. 2017 Oct 17. doi: 10.1002/pds.4336. [Epub ahead of print] Link to article on publisher's site
Pharmacoepidemiology and drug safety
Wood, Mollie E.; Lapane, Kate L.; van Gelder, Marleen M. H. J.; Rai, Dheeraj; and Nordeng, Hedvig M. E., "Making fair comparisons in pregnancy medication safety studies: An overview of advanced methods for confounding control" (2017). University of Massachusetts Medical School Faculty Publications. 1432.