UMass Chan Medical School Faculty Publications


Comparison of Home-Based Oral Fluid Rapid HIV Self-Testing Versus Mail-in Blood Sample Collection or Medical/Community HIV Testing By Young Adult Black, Hispanic, and White MSM: Results from a Randomized Trial

UMMS Affiliation

Department of Quantitative Health Sciences; Center for Health Policy and Research, Commonwealth Medicine

Publication Date


Document Type



Community-Based Research | Community Health and Preventive Medicine | Immune System Diseases | Virus Diseases


We aimed to determine in a randomized trial if young adult black, Hispanic, and white men-who-have-sex-with-men (YMSM) are more likely to complete home-based oral fluid rapid HIV self-testing than either mail-in blood sample collection or medical facility/community organization-based HIV testing. Stratified by race/ethnicity, participants were randomly assigned to use a free oral fluid rapid HIV self-test (n = 142), a free mail-in blood sample collection HIV test (n = 142), or be tested at a medical facility/community organization of their choice (n = 141). Of the 425 participants, completion of assigned test (66% oral fluid vs. 40% mail-in blood sample vs. 56% medical facility/community), willingness to refer (36% oral fluid vs. 20% mail-in blood sample vs. 26% medical facility/community), and legitimate referrals (58% oral fluid vs. 43% mail-in blood sample vs. 43% medical facility/community) were greater in the oral fluid rapid HIV self-test than the mail-in blood sample collection HIV test arm, but not the medical facility/community testing arm. There were no differences in assigned test completion by race/ethnicity. Although free home-based oral fluid rapid HIV self-testing showed moderate promise in facilitating HIV testing among black, Hispanic, and white YMSM, it did not lead to greater testing than directing these YMSM to medical facility/community HIV testing venues. Identifier: NCT02369627.


Clinical trial, HIV testing, Men-who-have-sex-with-men, Young adult

DOI of Published Version



AIDS Behav. 2017 May 24. doi: 10.1007/s10461-017-1802-x. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Journal/Book/Conference Title

AIDS and behavior

PubMed ID