Drosophilosophical: Re-thinking Adaptive Immunity in the Fly
Division of Infectious Diseases and Immunology, Department of Medicine
For decades, flies have been a model for innate immunity. In this issue of Cell, Tassetto et al. describe a mechanism for antiviral RNAi spreading that parallels mammalian adaptive immunity through reverse-transcribed vDNA circles and the systemic dissemination of small-RNA-containing exosomes.
DOI of Published Version
Cell. 2017 Apr 6;169(2):188-190. doi: 10.1016/j.cell.2017.03.032. Link to article on publisher's site
West CC, Silverman NS. (2017). Drosophilosophical: Re-thinking Adaptive Immunity in the Fly. University of Massachusetts Medical School Faculty Publications. https://doi.org/10.1016/j.cell.2017.03.032. Retrieved from https://escholarship.umassmed.edu/faculty_pubs/1290