UMass Chan Medical School Faculty Publications


Obstructive sleep apnea and weight loss treatment outcome among adults with metabolic syndrome

UMMS Affiliation

Department of Medicine, Division of Preventative and Behavioral Medicine; Department of Quantitative Health Sciences

Publication Date


Document Type



Behavior and Behavior Mechanisms | Health Psychology | Nervous System Diseases | Nutritional and Metabolic Diseases | Pathological Conditions, Signs and Symptoms | Physiological Processes | Respiratory Tract Diseases | Therapeutics


OBJECTIVE: The purpose of this study was to examine whether adults with obesity and metabolic syndrome who screen as high risk for obstructive sleep apnea (OSA) lose less weight as part of a weight loss intervention than those who screen as low risk.

METHOD: We conducted a secondary analysis of a randomized trial comparing 2 weight loss interventions consisting of dietary counseling for adults with obesity and metabolic syndrome. Participants were screened for sleep apnea using a validated screening questionnaire. Percent weight loss was calculated from weight measured at baseline and intervention end (12 months). Weight loss of 5% or greater was considered clinically significant. Multivariate linear and logistic regression models estimated the association between OSA screening status (high vs. low risk) and percent weight loss and clinically significant weight loss, adjusting for relevant covariates including body mass index and sleep duration.

RESULTS: Nearly half of participants (45.8%) screened as high risk for OSA. Participants who screened as high risk for OSA lost less weight (1.2% +/- 4.2% vs. 4.2% +/- 5.3%) and were less likely to lose 5% or greater (24.4% vs. 75.6%) than participants without OSA.

CONCLUSION: Among adults with obesity and metabolic syndrome, those at high risk for OSA lost less weight in response to a dietary counseling intervention than adults with low risk of OSA. Routine OSA screening should be considered as part of weight loss treatment programs. Additional research is needed to determine how to tailor weight loss treatment for those with high risk for OSA. (PsycINFO Database Record


UMCCTS funding

DOI of Published Version



Health Psychol. 2016 Dec;35(12):1316-1319. Epub 2016 Jun 13. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Journal/Book/Conference Title

Health psychology : official journal of the Division of Health Psychology, American Psychological Association

PubMed ID