University of Massachusetts Medical School Faculty Publications

 

This collection showcases journal articles, book chapters, and other publications and presentations written by faculty and researchers at the University of Massachusetts Medical School.

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Publications from 2021

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"Don't talk to them about goals of care": Understanding disparities in advance care planning, Deepshikha Charan Ashana, Noah D'Arcangelo, Priscilla K. Gazarian, Avni Gupta, Stephen Perez, Amanda J. Reich, Jennifer Tjia, Scott D. Halpern, Joel S. Weissman, and Keren Ladin

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Exposure to Weight Management Counseling Among Students at 8 U.S. Medical Schools, Karen M. Ashe, Alan C. Geller, Jyothi A. Pendharkar, Lori Pbert, Sybil L. Crawford, Melissa A. Clark, Christine F. Frisard, Cassie A. Eno, Jamie Faro, and Judith K. Ockene

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IFNγ and iNOS-mediated alterations in the bone marrow and thymus and its impact on Mycobacterium avium-induced thymic atrophy [preprint], Palmira Barreira-Silva, Rita Melo-Miranda, Claudia Nobrega, Susana Roque, Cláudia Serre-Miranda, Margarida Borges, Daniela de Sá Calçada, Samuel M. Behar, Rui Appelberg, and Margarida Correia-Neves

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A randomized, controlled trial of the safety planning intervention: Research design and methods, Edwin D. Boudreaux, Barbara Stanley, Kelly L. Green, Hanga Galfalvy, and Gregory K. Brown

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Development and psychometric evaluation of the Social Connectedness Index in nursing home residents with Alzheimer's disease and dementia using the Minimum Data Set 3.0, Carol A. Bova, William M. Jesdale, Attah Mbrah, Lynn Botelho, and Kate L. Lapane

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Classification and prediction of post-trauma outcomes related to PTSD using circadian rhythm changes measured via wrist-worn research watch in a large longitudinal cohort, Ayse Selin Cakmak, John P. Haran, and Gari D. Clifford

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Opioid Use and Driving Performance, Keaton T. Cameron-Burr, Albert Conicella, and Mark J. Neavyn

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Realize, Analyze, Engage (RAE): A Digital Tool to Support Recovery from Substance Use Disorder, Stephanie P. Carreiro, Melissa Taylor, Sloke Shrestha, Megan Reinhardt, Nicole Gilbertson, and Premananda Indic

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Neuronal post-developmentally acting SAX-7S/L1CAM can function as cleaved fragments to maintain neuronal architecture in C. elegans [preprint], Virginie E. Desse, Cassandra R. Blanchette, Paola N. Perrat, and Claire Y. Benard

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Comparing recruitment strategies for a digital smoking cessation intervention: Technology-assisted peer recruitment, social media, ResearchMatch, and smokefree.gov, Jamie Faro, Catherine S. Nagawa, Elizabeth Aaker Orvek, Bridget M. Smith, Amanda C. Blok, Thomas K. Houston, Ariana Kamberi, Jeroan J. Allison, Sharina D. Person, and Rajani S. Sadasivam

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Emergence and evolution of Plasmodium falciparum histidine-rich protein 2 and 3 deletion mutant parasites in Ethiopia [preprint], Sindew M. Feleke, Nicholas J. Hathaway, Jane Cunningham, and Jonathan B. Parr

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JUN Amino-Terminal Kinase 1 Signaling in the Proximal Tubule Causes Cell Death and Acute Renal Failure in Rat and Mouse Models of Renal Ischemia/Reperfusion Injury, Keren Grynberg, Elyce Ozols, William R. Mulley, Roger J. Davis, Richard A. Flavell, David J. Nikolic-Paterson, and Frank Y. Ma

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An expanded benchmark for antibody-antigen docking and affinity prediction reveals insights into antibody recognition determinants, Johnathan D. Guest, Thom Vreven, Jing Zhou, Iain Moal, Jeliazko R. Jeliazkov, Jeffrey J. Gray, Zhiping Weng, and Brian G. Pierce

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Quantifying the regulatory role of individual transcription factors in Escherichia coli [preprint], Sunil Guharajan, Shivani Chhabra, Vinuselvi Parisutham, and Robert C. Brewster

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Effect of a Multifaceted Clinical Pharmacist Intervention on Medication Safety After Hospitalization in Persons Prescribed High-risk Medications: A Randomized Clinical Trial, Jerry H. Gurwitz, Alok Kapoor, Lawrence D. Garber, Kathleen M. Mazor, Joann L. Wagner, Sarah L. Cutrona, Sonal Singh, Abir O. Kanaan, Jennifer L. Donovan, Sybil L. Crawford, Kathryn Anzuoni, Timothy J. Konola, Yanhua Zhou, and Terry S. Field

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Human antibody immune responses are personalized by selective removal of MHC-II peptide epitopes [preprint], Matias Gutiérrez-González, Padma P. Nanaware, Liying Lu, Lawrence J. Stern, and Brandon J. DeKosky

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SWI/SNF senses carbon starvation with a pH-sensitive low complexity sequence [preprint], J. Ignacio Gutiérrez, Gregory P. Brittingham, Yonca Karadeniz, Kathleen D. Tran, Arnob Dutta, Alex S. Holehouse, Craig L. Peterson, and Liam J. Holt

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Presentation, Treatment, and Outcomes of Older Adults Hospitalized for Acute Myocardial Infarction according to Cognitive Status: the SILVER-AMI Study, Alexandra M. Hajduk, Jane S. Saczynski, Sui Tsang, Mary E. Geda, John A. Dodson, Gregory M. Ouellet, Robert J. Goldberg, and Sarwat I. Chaudhry

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A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21, Myoung Souk Han, Rachel J. Perry, Joao-Paulo Camporez, Philipp E. Scherer, Gerald I. Shulman, Guangping Gao, and Roger J. Davis

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Aging, Frailty, and the Microbiome - How Dysbiosis Influences Human Aging and Disease, John P. Haran and Beth A. McCormick

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The high prevalence of Clostridioides difficile among nursing home elders associates with a dysbiotic microbiome, John P. Haran, Doyle V. Ward, Shakti K. Bhattarai, Ethan Loew, Protiva Dutta, Amanda Higgins, Beth A. McCormick, and Vanni Bucci

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Prognostic neuroimaging biomarkers of trauma-related psychopathology: resting-state fMRI shortly after trauma predicts future PTSD and depression symptoms in the AURORA study, Nathaniel G. Harnett, John P. Haran, and Jennifer S. Stevens

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Host tropism determination by convergent evolution of immunological evasion in the Lyme disease system [preprint], Thomas M. Hart; Alan P. Dupuis, II; Danielle M. Tufts; Anna M. Blom; Simon Starkey; Ryan O. M. Rego; Sanjay Ram; Peter Kraiczy; Laura D. Kramer; Maria A. Diuk-Wasser; Sergios-Orestis Kolokotronis; and Yi-Pin Lin

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The Impact of a Randomized Controlled Trial of a Lifestyle Intervention on Sleep Among Latina Postpartum Women, Marquis Hawkins, Bess Marcus, Penelope Pekow, Milagros C. Rosal, Katherine L. Tucker, Rebecca M. C. Spencer, and Lisa Chasan-Taber

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YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation [preprint], Lizhi He, Henry E. Pratt, Fengxiang Wei, Mingshi Gao, Zhiping Weng, and Kevin Struhl

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Cryo-TEM simulations of amorphous radiation-sensitive samples using multislice wave propagation [preprint], Benjamin A. Himes and Nikolaus Grigorieff

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The Mycobacterium tuberculosis transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality [preprint], Adrian Jinich, Anisha Zaveri, Michael A. DeJesus, Emanuel Flores-Bautista, Clare M. Smith, Christopher M. Sassetti, Jeremy M. Rock, Sabine Ehrt, Dirk Schnappinger, Thomas R. Ioerger, and Kyu Rhee

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Dietary Habits and Medications to Control Hypertension among Women of Child-bearing Age in the United States from 2001-2016, Lara C. Kovell, Benjamin Maxner, M. Didem Ayturk, Tiffany Moore Simas, Colleen M> Harrington, David D. McManus, Paula Gardiner, Gerard P. Aurigemma, and Stephen P. Juraschek

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Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons: US Preventive Services Task Force Recommendation Statement, Alex H. Krist and Lori Pbert

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Screening for Asymptomatic Carotid Artery Stenosis: US Preventive Services Task Force Recommendation Statement, Alex H. Krist and Lori Pbert

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Screening for Hearing Loss in Older Adults: US Preventive Services Task Force Recommendation Statement, Alex H. Krist and Lori Pbert

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Screening for Lung Cancer: US Preventive Services Task Force Recommendation Statement, Alex H. Krist and Lori Pbert

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Priority-Setting to Address the Geriatric Pharmacoparadox for Pain Management: A Nursing Home Stakeholder Delphi Study, Kate L. Lapane, Catherine E. Dube, Anne L. Hume, Jennifer Tjia, William M. Jesdale, Jayne Pawasauskas, and Dmitry Khodyakov

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Social support and strain and emotional distress among Latinos in the northeastern United States, Shir Lerman Ginzburg, Stephenie C. Lemon, Eric Romo, and Milagros C. Rosal

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Inhibiting HTLV-1 Protease: A Viable Antiviral Target, Gordon J. Lockbaum, Mina Henes, Nathaniel Talledge, Linah Rusere, Klajdi Kosovrasti, Ellen A. Nalivaika, Mohan Somasundaran, Akbar Ali, Louis M. Mansky, Nese Kurt Yilmaz, and Celia A. Schiffer

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Dysfunctional Eating Behaviors and Dietary Intake in Puerto Rico, Andrea A. Lopez-Cepero, Josiemer Mattei, Christine F. Frisard, Emily Riseberg, Julio Jimenez, Stephenie C. Lemon, and Milagros C. Rosal

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CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection [preprint], Yu-Jung Lu, Palmira Barreira-Silva, Shayla Boyce, Jennifer Powers, Kelly Cavallo, and Samuel M. Behar

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National Trends in Statin Use among the United States Nursing Home Population (2011-2016), Deborah Mack, Anne L. Hume, Jennifer Tjia, and Kate L. Lapane

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Interactions of APOBEC3s with DNA and RNA, Atanu Maiti, Shurong Hou, Celia A. Schiffer, and Hiroshi Matsuo

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Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond, Ashley N. Matthew, Florian Leidner, Gordon J. Lockbaum, Mina Henes, Jacqueto Zephyr, Shurong Hou, Nageswara Rao Desaboini, Jennifer Timm, Linah N. Rusere, Debra A. Ragland, Janet L. Paulsen, Kristina L. Prachanronarong, Djade I. Soumana, Ellen A. Nalivaika, Nese Kurt Yilmaz, Akbar Ali, and Celia A. Schiffer

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Developing network adequacy standards for VA Community Care, Kristin M. Mattocks, A. Rani Elwy, Elizabeth M. Yano, Justin Giovannelli, Michael Adelberg, Michelle A. Mengeling, Kristin J. Cunningham, and Kameron L. Matthews

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Local Control For High-Grade Nonrhabdomyosarcoma Soft Tissue Sarcoma Assigned to Radiation Therapy on ARST0332: A Report From the Childrens Oncology Group, Lynn Million, Frances Laurie, Karen Morano, and Thomas J. FitzGerald

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Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans, Tatsunori Miyata, Bruce A. Barton, and Laura E. Nagy

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Quantifying and Mitigating Motor Phenotypes Induced by Antisense Oligonucleotides in the Central Nervous System [preprint], Michael P. Moazami, Julia M. Rembetsy-Brown, Feng Wang, Pranathi Meda Krishnamurthy, Alexandra Weiss, Miklos G. Marosfoi, Robert M. King, Mona Motwani, Heather L. Gray-Edwards, Katherine A. Fitzgerald, Robert H. Brown Jr., and Jonathan K. Watts

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Site-specific incorporation of citrulline into proteins in mammalian cells, Santanu Mondal, Shu Wang, Yunan Zheng, Sudeshna Sen, Abhishek Chatterjee, and Paul R. Thompson

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Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies [preprint], Frauke Muecksch, Shurong Hou, Celia A. Schiffer, Michel Nussenzweig, Pamela J. Bjorkman, Theodora Hatziioannou, and Paul Bieniasz

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Core Muscle and Adductor Injury, Timothy J. Mulry, Paul E. Rodenhouse, and Brian D. Busconi

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Humoral and cell-mediated response in colostrum after exposure to severe acute respiratory syndrome coronavirus 2 [preprint], Vignesh Narayanaswamy, Brian Pentecost, Dominique Alfandari, Emily Chin, Kathleen Minor, Alyssa Kastrinakis, Tanya Lieberman, Kathleen F. Arcaro, and Heidi Leftwich

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Machine learning-based outcome prediction and novel hypotheses generation for substance use disorder treatment, Murtaza Nasir, Nichalin S. Summerfield, Asil Oztekin, Margaret Knight, Leland K. Ackerson, and Stephanie P. Carreiro

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NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP), Jeffry C. Nichols, Celia A. Schiffer, and William E. Royer

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Supporting families of children with overweight and obesity to live healthy lifestyles: Design and rationale for the Fitline cluster randomized controlled pediatric practice-based trial, Lori Pbert, Michelle K. Trivedi, Susan Druker, Jennifer Bram, Barbara C. Olendzki, Sybil L. Crawford, Christine F. Frisard, Victoria A. Andersen, Molly E. Waring, Karen M. Clements, Kristin Schneider, and Alan C. Geller

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Performance and Implementation Evaluation of the Abbott BinaxNOW Rapid Antigen Test in a High-throughput Drive-through Community Testing Site in Massachusetts [preprint], Nira R. Pollock, Lawrence C. Madoff, and Sandra Smole

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Feasibility of Implementation Mapping for Integrative Medical Group Visits, Isabel J. Roth, Malik K. Tiedt, Jessica L. Barnhill, Kristopher R. Karvelas, Keturah R. Faurot, Susan Gaylord, Paula Gardiner, Vanessa E. Miller, and Jennifer Leeman

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Study design and rationale for a randomized controlled trial to assess effectiveness of stochastic vibrotactile mattress stimulation versus standard non-oscillating crib mattress for treating hospitalized opioid-exposed newborns, Elisabeth B. Salisbury, Debra Bogen, Mark A. Vining, Dane Netherton, Nicolas Rodriguez, Tory Bruch, Cheryl Burns, Emily Erceg, Barbara Glidden, M. Didem Ayturk, Sanjay Aurora, Toby Yanowitz, Bruce A. Barton, and Sue Beers

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Bridging the evidence-to-practice gap: a stepped-wedge cluster randomized controlled trial evaluating practice facilitation as a strategy to accelerate translation of a multi-level adherence intervention into safety net practices, Antoinette Schoenthaler, Franzenith De La Calle, Amanda Soto, Derrel Barrett, Jocelyn Cruz, Leydi Payano, Marina Rosado, Samrachana Adhikari, Gbenga Ogedegbe, and Milagros C. Rosal

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CNBP, REL, and BHLHE40 variants are associated with IL-12 and IL-10 responses and tuberculosis risk [preprint], Javeed A. Shah, Christopher M. Sassetti, and Katherine A. Fitzgerald

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Innate lymphoid cells and disease tolerance in SARS-CoV-2 infection [preprint], Noah J. Silverstein, Yetao Wang, Zachary Manickas-Hill, Claudia C. Carbone, Ann Dauphin, MGH COVID-19 Collection & Processing Team, Jonathan Z. Li, Bruce D. Walker, Xu G. Yu, and Jeremy Luban

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Trends in the magnitude of chronic conditions in patients hospitalized with a first acute myocardial infarction, Mayra Tisminetzky, Ruben Miozzo, Joel M. Gore, Jerry H. Gurwitz, Darleen M. Lessard, Jorge Yarzebski, Edgard A. Granillo, Hawa Ozien Abu, and Robert J. Goldberg

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Somatic piRNAs and Transposons are Differentially Regulated During Skeletal Muscle Atrophy and Programmed Cell Death [preprint], Junko Tsuji, Travis Thomson, Christine Brown, Subhanita Ghosh, William E. Theurkauf, Zhiping Weng, and Lawrence M. Schwartz

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GWAS-associated Variants, Non-genetic Factors, and Transient Transcriptome in Multiple Sclerosis Etiopathogenesis: a Colocalization Analysis [preprint], Renato Umeton, Gianmarco Bellucci, Rachele Bigi, Silvia Romano, Maria Chiara Buscarinu, Roberta Reniè, Virginia Rinaldi, Raffaella Pizzolato Umeton, Emanuele Morena, Carmela Romano, Rosella Mechelli, Marco Salvetti, and Giovanni Ristori

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Prognostic value of geriatric conditions for death and bleeding in older patients with atrial fibrillation, Weijia Wang, Darleen M. Lessard, Jane S. Saczynski, Robert J. Goldberg, Jordy Mehawej, Ely Gracia, and David D. McManus

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The Intestinal and Oral Microbiomes Are Robust Predictors of COVID-19 Severity the Main Predictor of COVID-19-related Fatality [preprint], Doyle V. Ward, Shakti Bhattarai, Mayra Rojas-Correa, Ayan Purkayastha, Devon Holler, Ming Da Qu, William G. Mitchell, Jason D. Yang, Samuel Fountain, Abigail Zeamer, Catherine Forconi, Gavin Fujimori, Boaz Odwar, Caitlin Cawley, Beth A. McCormick, Ann M. Moormann, Mireya Wessolossky, Vanni Bucci, and Ana Maldonado-Contreras

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Challenging Diagnosis of Stickler Syndrome in a Patient with Premature Osteoarthritis: A Case Report, Mohamed A. Yousef and David C. Ayers

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Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes, Tianxiong Yu, Kaili Fan, Deniz M. Ozata, Gen Zhang, Yu Fu, William E. Theurkauf, Phillip D. Zamore, and Zhiping Weng

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A benchmark and an algorithm for detecting germline transposon insertions and measuring de novo transposon insertion frequencies, Tianxiong Yu, Xiao Huang, Shengqian Dou, Xiaolu Tang, Shiqi Luo, William E. Theurkauf, Jian Lu, and Zhiping Weng

Publications from 2020

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Impact of global and national crises on people with severe mental illness, Margarita Abi Zeid Daou, Uriel Halbreich, and Jeffrey L. Geller

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Systematic evaluation of chromosome conformation capture assays [preprint], Betul Akgol-Oksuz, Liyan Yang, Sergey V. Venev, Nils Krietenstein, Krishna M. Parsi, Hakan Ozadam, Marlies E. Oomen, Ankita Nand, Hui Mao, Ryan M.J. Genga, Rene Maehr, Oliver J. Rando, Johan H. Gibcus, and Job Dekker

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Primary Care Providers Underutilize Breast Screening MRI for High-Risk Women, Nita Amornsiripanitch, Sarah M. Ameri, and Robert J. Goldberg

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Long-Term Exposure to Fine Particulate Matter, Lung Function and Cognitive Performance: A Prospective Dutch Cohort Study on the Underlying Routes [preprint], Benjamin Aretz, Fanny Janssen, Judith M. Vonk, Michael T. Heneka, H. Marike Boezen, and Gabriele Doblhammer

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Progressive Cactus is a multiple-genome aligner for the thousand-genome era, Joel Armstrong, Elinor K. Karlsson, Guojie Zhang, and Benedict Paten

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Cell cycle-associated expression patterns predict gene function in mycobacteria [preprint], Aditya Bandekar, Sishir Subedi, Thomas Ioerger, and Christopher M. Sassetti

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Two cases of acute anterolateral compartment syndrome following inversion ankle injuries, Jugert Bango, Evan Zhang, Daniel L. Aaron, and Amna Diwan

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mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding [preprint], Chen Bao, Sarah Loerch, Clarence Ling, Andrei A. Korostelev, Nikolaus Grigorieff, and Dmitri N. Ermolenko

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A Physician's Guide for Workers' Return to Work during COVID-19 Pandemic, Marcos C. Baptista, Wayne N. Burton, Brent Pawlecki, and Glenn Pransky

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Sex Differences in Substance Use and Misuse: A Toxicology Investigators' Consortium (ToxIC) Registry Analysis, Gillian A. Beauchamp, Jennifer L. Carey, Mikayla B. Hurwitz, Briana N. Tully, Matthew D. Cook, Robert D. Cannon, Kenneth D. Katz, Andrew L. Koons, Hope Kincaid, and Marna Rayl. Greenberg

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Coxsackievirus B Type 4 Infection in beta Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 Silencing, Hugo Bernard, Ana Teijeiro, Almudena Chaves-Perez, Cristian Perna, Basanthi Satish, Anna Novials, Jennifer P. Wang, and Nabil Djouder

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Brief Self-Compassion Training Alters Neural Responses to Evoked Pain for Chronic Low Back Pain: A Pilot Study, Michael P. Berry, Jacqueline Lutz, Zev Schuman-Olivier, Christopher Germer, Susan Pollak, Robert R. Edwards, Paula Gardiner, Gaelle Desbordes, and Vitaly Napadow

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Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis [preprint], Semir Beyaz, Deniz M. Ozata, Alper Kucukural, Stuart H. Orkin, and Omer H. Yilmaz

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High-throughput modeling and scoring of TCR-pMHC complexes to predict cross-reactive peptides, Tyler M. Borrman, Brian G. Pierce, Thom Vreven, Brian M. Baker, and Zhiping Weng

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Emergency department safety assessment and follow-up evaluation 2: An implementation trial to improve suicide prevention, Edwin D. Boudreaux, Brianna L. Haskins, Celine Larkin, Lori Pelletier, Sharon A. Johnson, Barbara Stanley, Gregory Brown, Kristin M. Mattocks, and Yunsheng Ma

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Pediatric Resident Training in Tobacco Control and the Electronic Health Record, Rachel Boykan, Julie Gorzkowski, Robert J. Wellman, Brian P. Jenssen, Jonathan D. Klein, Jessica Krugman, Lori Pbert, and Ramzi G. Salloum

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Pain Management in Breast Surgery: Recommendations of a Multidisciplinary Expert Panel-The American Society of Breast Surgeons, David R. Brenin, Jill R. Dietz, Jennifer Baima, Gloria Cheng, Joshua Froman, Christine Laronga, Ayemoethu Ma, Michele A. Manahan, Edward R. Mariano, Kristin Rojas, Anneke T. Schroen, Nassima Ait-Daoud Tiouririne, Lisa S. Wiechmann, and Roshni Rao

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C-SSRS performance in emergency department patients at high risk for suicide, Lily A. Brown, Edwin D. Boudreaux, Sarah A. Arias, Ivan W. Miller, Alexis M. May, Carlos A. Camargo Jr., Craig J. Bryan, and Michael F. Armey

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Effective Mentoring of Novice Nurses during a Healthcare Crisis, Venise Bryan and Joan Vitello-Cicciu

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Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase [preprint], Yi Cai, Eleni Jaecklein, Jared Mackenzie, Kadamba Papavinasasundaram, Michigan State University, Xinchun Chen, Africa Health Research Institute, and Christopher M. Sassetti

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Asylum Body Work, Lucy M. Candib

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Single-cell analysis of upper airway cells reveals host-viral dynamics in influenza infected adults [preprint], Yuming Cao, Zhiru Guo, Pranitha Vangala, Elisa Donnard, Ping Liu, Patrick McDonel, Jose Ordovas Montanes, Alex K. Shalek, Robert W. Finberg, Jennifer P. Wang, and Manuel Garber

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Current reporting of usability and impact of mHealth interventions for substance use disorder: A systematic review, Stephanie Carreiro, Mark Newcomb, Rebecca Leach, Simon Ostrowski, Edwin D. Boudreaux, and Daniel J. Amante

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Concomitant rotator cuff repair and instability surgery provide good patient-reported functional outcomes in patients aged 40 years or older with shoulder dislocation, Wayne W. Chan, Tyler J. Brolin, Ocean Thakar, Manan S. Patel, Daniel S. Sholder, Joseph A. Abboud, and Charles L. Getz

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The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans [preprint], Daniel A. Chaves, Hui Dai, Lichao Li, James J. Moresco, Myung Eun Oh, Darryl Conte Jr., John R. Yates III, Craig C. Mello, and Weifeng Gu

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Linker histone H1.8 inhibits chromatin-binding of condensins and DNA topoisomerase II to tune chromosome compaction and individualization [preprint], Pavan Choppakatla, Bastiaan Dekker, Erin E. Cutts, Alessandro Vannini, Job Dekker, and Hironori Funabiki

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Characterization of Viral Insulins Reveals White Adipose Tissue Specific Effects in Mice [preprint], Martina Chrudinová, Francois Moreau, Hye Lim Noh, Terezie Páníková, Lenka Žáková, Randall H. Friedline, Francisco A. Valenzuela, Jason K. Kim, Jiri Jiracek, C. Ronald Kahn, and Emrah Altindis

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Improving patient-provider communication about chronic pain: development and feasibility testing of a shared decision-making tool, Nananda Col, Stephen Hull, Vicky Springmann, Long Ngo, Ernie Merritt, Susan Gold, Michael Sprintz, Noel Genova, Noah Nesin, Brenda Tierman, Frank Sanfilippo, Richard Entel, and Lori Pbert

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The meadow jumping mouse genome and transcriptome suggest mechanisms of hibernation [preprint], Qian Cong, Ethan A. Brem, Jing Zhang, Jessica Alfoldi, Jeremy Johnson, Elinor K. Karlsson, Kerstin Lindblad-Toh, Jason L. Malaney, and William J. Israelsen

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Flexibility and constraint in preimplantation gene regulation in mouse [preprint], Colin C. Conine, Marina Krykbaeva, Lina Song, Robert C. Brewster, Nir Friedman, and Oliver J. Rando

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Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism, Maria Crespo, Norman J. Kennedy, Roger J. Davis, Nuria Matesanz, Magdalena Leiva, and Guadalupe Sabio

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Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma, Francisco Javier Cubero, Mohamed Ramadan Mohamed, Marius M. Woitok, Gang Zhao, Maximilian Hatting, Yulia A. Nevzorova, Chaobo Chen, Johannes Haybaeck, Alain de Bruin, Matias A. Avila, Mark V. Boekschoten, Roger J. Davis, and Christian Trautwein

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Does Home Remedy Use Contribute to Medication Nonadherence Among Blacks with Hypertension, Yendelela L. Cuffee, Milagros C. Rosal, J. Lee Hargraves, Becky A. Briesacher, Suzanne Akuley, Noof Altwatban, Sandral Hullett, and Jeroan J. Allison

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Silencing Trisomy 21 with XIST in Neural Stem Cells Promotes Neuronal Differentiation, Jan T. Czerminski and Jeanne B. Lawrence

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Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates [preprint], Joana Damas, Elinor K. Karlsson, and Harris A. Lewin