University of Massachusetts Medical School Faculty Publications

 

This collection showcases journal articles, book chapters, and other publications and presentations written by faculty and researchers at the University of Massachusetts Medical School.

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Publications from 2020

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Primary Care Providers Underutilize Breast Screening MRI for High-Risk Women, Nita Amornsiripanitch, Sarah M. Ameri, and Robert J. Goldberg

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Cell cycle-associated expression patterns predict gene function in mycobacteria [preprint], Aditya Bandekar, Sishir Subedi, Thomas Ioerger, and Christopher M. Sassetti

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mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding [preprint], Chen Bao, Sarah Loerch, Clarence Ling, Andrei A. Korostelev, Nikolaus Grigorieff, and Dmitri N. Ermolenko

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Brief Self-Compassion Training Alters Neural Responses to Evoked Pain for Chronic Low Back Pain: A Pilot Study, Michael P. Berry, Jacqueline Lutz, Zev Schuman-Olivier, Christopher Germer, Susan Pollak, Robert R. Edwards, Paula Gardiner, Gaelle Desbordes, and Vitaly Napadow

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Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis [preprint], Semir Beyaz, Deniz M. Ozata, Alper Kucukural, Stuart H. Orkin, and Omer H. Yilmaz

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Emergency department safety assessment and follow-up evaluation 2: An implementation trial to improve suicide prevention, Edwin D. Boudreaux, Brianna L. Haskins, Celine Larkin, Lori Pelletier, Sharon A. Johnson, Barbara Stanley, Gregory Brown, Kristin M. Mattocks, and Yunsheng Ma

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Pain Management in Breast Surgery: Recommendations of a Multidisciplinary Expert Panel-The American Society of Breast Surgeons, David R. Brenin, Jill R. Dietz, Jennifer Baima, Gloria Cheng, Joshua Froman, Christine Laronga, Ayemoethu Ma, Michele A. Manahan, Edward R. Mariano, Kristin Rojas, Anneke T. Schroen, Nassima Ait-Daoud Tiouririne, Lisa S. Wiechmann, and Roshni Rao

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C-SSRS performance in emergency department patients at high risk for suicide, Lily A. Brown, Edwin D. Boudreaux, Sarah A. Arias, Ivan W. Miller, Alexis M. May, Carlos A. Camargo Jr., Craig J. Bryan, and Michael F. Armey

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Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase [preprint], Yi Cai, Eleni Jaecklein, Jared Mackenzie, Kadamba Papavinasasundaram, Michigan State University, Xinchun Chen, Africa Health Research Institute, and Christopher M. Sassetti

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Asylum Body Work, Lucy M. Candib

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Single-cell analysis of upper airway cells reveals host-viral dynamics in influenza infected adults [preprint], Yuming Cao, Zhiru Guo, Pranitha Vangala, Elisa Donnard, Ping Liu, Patrick McDonel, Jose Ordovas Montanes, Alex K. Shalek, Robert W. Finberg, Jennifer P. Wang, and Manuel Garber

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Current reporting of usability and impact of mHealth interventions for substance use disorder: A systematic review, Stephanie Carreiro, Mark Newcomb, Rebecca Leach, Simon Ostrowski, Edwin D. Boudreaux, and Daniel J. Amante

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The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans [preprint], Daniel A. Chaves, Hui Dai, Lichao Li, James J. Moresco, Myung Eun Oh, Darryl Conte Jr., John R. Yates III, Craig C. Mello, and Weifeng Gu

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Characterization of Viral Insulins Reveals White Adipose Tissue Specific Effects in Mice [preprint], Martina Chrudinová, Francois Moreau, Hye Lim Noh, Terezie Páníková, Lenka Žáková, Randall H. Friedline, Francisco A. Valenzuela, Jason K. Kim, Czech Academy of Sciences, Harvard Medical School, and Boston College

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Flexibility and constraint in preimplantation gene regulation in mouse [preprint], Colin C. Conine, Marina Krykbaeva, Lina Song, Robert C. Brewster, Nir Friedman, and Oliver J. Rando

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Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma, Francisco Javier Cubero, Mohamed Ramadan Mohamed, Marius M. Woitok, Gang Zhao, Maximilian Hatting, Yulia A. Nevzorova, Chaobo Chen, Johannes Haybaeck, Alain de Bruin, Matias A. Avila, Mark V. Boekschoten, Roger J. Davis, and Christian Trautwein

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Does Home Remedy Use Contribute to Medication Nonadherence Among Blacks with Hypertension, Yendelela L. Cuffee, Milagros C. Rosal, J. Lee Hargraves, Becky A. Briesacher, Suzanne Akuley, Noof Altwatban, Sandral Hullett, and Jeroan J. Allison

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Silencing Trisomy 21 with XIST in Neural Stem Cells Promotes Neuronal Differentiation, Jan T. Czerminski and Jeanne B. Lawrence

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Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates [preprint], Joana Damas, Elinor K. Karlsson, and Harris A. Lewin

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Midbrain Dopamine Controls Anxiety-like Behavior by Engaging Unique Interpeduncular Nucleus Microcircuitry, Steven R. DeGroot, Rubing Zhao-Shea, Leeyup Chung, Paul M. Klenowski, Fangmiao Sun, Susanna Molas-Casacuberta, Paul D. Gardner, Yulong Li, and Andrew R. Tapper

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CD4 Effectors Need to Recognize Antigen Locally to Become Cytotoxic CD4 and Follicular Helper T Cells [preprint], Priyadharshini Devarajan, Allen M. Vong, Catherine H. Castonguay, Bianca L. Bautista, Michael C. Jones, Olivia Kugler-Umana, Karen A. Kelly, and Susan L. Swain

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Single Cell Transcriptomics Reveals Dysregulated Cellular and Molecular Networks in a Fragile X Syndrome model [preprint], Elisa Donnard, Huan Shu, and Manuel Garber

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Bioinformatics Core Survey Highlights the Challenges Facing Data Analysis Facilities, Julie A. Dragon, Chris Gates, Shannan Ho Sui, John N. Hutchinson, R. Krishna Murthy Karuturi, Alper Kucukural, Shawn Polson, Alberto Riva, Matthew Lee Settles, Jyothi Thimmapuram, and Stuart S. Levine

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Competition for MCM Loading at Origins Establishes Replication Timing Patterns [preprint], Livio Dukaj and Nicholas R. Rhind

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Non-Adherence Tree Analysis (NATA) - an adherence improvement framework: a COVID-19 case study [preprint], Ernest Edifor, Regina Brown, Paul Smith, and Rick Kossik

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Expanded encyclopaedias of DNA elements in the human and mouse genomes, ENCODE Project Consortium, Jill E. Moore, Michael J. Purcaro, Henry E. Pratt, Xiao-Ou Zhang, Shaimae I. Elhajjajy, Jack Huey, Job Dekker, J. Michael Cherry, Richard M. Myers, Bing Ren, Brenton R. Graveley, Mark B. Gerstein, Len A. Pennacchio, Michael P. Snyder, Bradley E. Bernstein, Barbara Wold, Ross C. Hardison, Thomas R. Gingeras, John A. Stamatoyannopoulos, and Zhiping Weng

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Perspectives on ENCODE, ENCODE Project Consortium, Michael P. Snyder, Jill E. Moore, and Zhiping Weng

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Diagnostic and Prognostic Significance of Complement in Patients with Alcohol-associated Hepatitis, Xiude Fan, Rebecca L. McCullough, Emily Huang, Annette Bellar, Adam Kim, Kyle L. Poulsen, Craig J. McClain, Mack Mitchell, Arthur J. McCullough, Svetlana Radaeva, Bruce A. Barton, Gyongyi Szabo, Srinivasan Dasarathy, Daniel M. Rotroff, and Laura E. Nagy

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A longitudinal implementation evaluation of a physical activity program for cancer survivors: LIVESTRONG(R) at the YMCA, Jamie Faro, Hannah Arem, Ann-Hilary Heston, Katherine H. Hohman, Heather Hodge, Bo Wang, Stephenie C. Lemon, Thomas K. Houston, and Rajani S. Sadasivam

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A Translational Model for Venous Thromboembolism: MicroRNA Expression in Hibernating Black Bears, Amanda Fazzalari, Giacomo Basadonna, Alper Kucukural, Kahraman Tanriverdi, Milka Koupenova-Zamor, Eric W. Dickson, Meghan Blackwood, Christian Mueller, Jane E. Freedman, and Mitchell A. Cahan

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Simultaneous Epigenetic Perturbation and Genome Imaging Reveal Distinct Roles of H3K9me3 in Chromatin Architecture and Transcription [preprint], Ying Feng, Yao Wang, Xiangnan Wang, Xiaohui He, Chen Yang, Ardalan Naseri, Thoru Pederson, Jing Zheng, Shaojie Zhang, Xiao Xiao, Wei Xie, and Hanhui Ma

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Translating clinical and patient-reported data to tailored shared decision reports with predictive analytics for knee and hip arthritis, Patricia D. Franklin, Hua Zheng, Christina Bond, and Danielle C. Lavallee

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Cytosine methylation dynamics during post-testicular sperm maturation in mammals [preprint], Carolina Galan, Ryan W. Serra, Fengyun Sun, Vera Rinaldi, Colin C. Conine, and Oliver J. Rando

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Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism [preprint], Christl Gaubitz, Xingchen Liu, Joseph Magrino, Nicholas P. Stone, Jacob Landeck, Mark Hedglin, and Brian A. Kelch

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Multimodality imaging of adult rhabdomyosarcoma: the added value of hybrid imaging, Nicolo Gennaro, Andrea Marrari, Salvatore Lorenzo Renne, Ferdinando Carlo Maria Cananzi, Vittorio Lorenzo Quagliuolo, Lucia Di Brina, Marta Scorsetti, Giovanna Pepe, Arturo Chiti, Armando Santoro, Luca Balzarini, Letterio S. Politi, and Alexia Francesca Bertuzzi

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Melting dsDNA donor molecules potentiates precision genome editing in C. elegans [preprint], Krishna S. Ghanta and Craig C. Mello

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The neuroanatomy and neurochemistry of sleep-wake control, Heinrich S. Gompf and Christelle Anaclet

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Outside Our Walls: the Case for City-Wide Collaboration to Reduce Disparities, Jennifer S. Haas, Stephenie C. Lemon, Karen M. Freund, Tracy A. Battaglia, and Translating Research Into Practice (TRIP) Consortium Writing Group

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A polymer gel index-matched to water enables diverse applications in fluorescence microscopy [preprint], Xiaofei Han, Yijun Su, and Hamilton White

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A Decline in Walking Speed is Associated with Incident Knee Replacement in Adults with and at Risk for Knee Osteoarthritis, Matthew S. Harkey, Kate L. Lapane, Shao-Hsien Liu, Grace H. Lo, Timothy E. McAlindon, and Jeffrey B. Driban

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Single Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis [preprint], Felipe Henriques, Alexander H. Bedard, Adilson L. Guilherme, Mark Kelly, Lawrence M. Lifshitz, Karl D. Bellve, Leslie Rowland, Batuhan Yenilmez, Shreya Kumar, Yetao Wang, Jeremy Luban, and Michael P. Czech

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Mechanisms and Functions of Chromosome Compartmentalization, Erica M. Hildebrand and Job Dekker

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Succination inactivates gasdermin D and blocks pyroptosis, Fiachra Humphries, Liraz Shmuel-Galia, Natalia Ketelut-Carneiro, Ruth Wilson, Zhaozhao Jiang, Farnaz Khalighinejad, Khaja Muneeruddin, Scott A. Shaffer, Carolina Ionete, Paul R. Thompson, and Katherine A. Fitzgerald

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Precision Cas9 Genome Editing in vivo with All-in-one, Self-targeting AAV Vectors [preprint], Raed Ibraheim, Phillip W. L. Tai, Aamir Mir, Nida Javeed, Jiaming Wang, Tomas Rodriguez, Samantha J. Nelson, Eraj Khokhar, Esther Mintzer, Stacy Maitland​, Yueying Cao, Guangping Gao, and Erik J. Sontheimer

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The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation [preprint], Anthony N. Imbalzano, Hanna Witwicka, and Tapan Sharma

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CryoEM Structure of CtBP2 Confirms Tetrameric Architecture [preprint], Anne M. Jecrois, M. Michael Dcona, Xiaovan Deng, Dipankar Bandyopadhyay, Steven R. Grossman, Celia A. Schiffer, and William E. Royer

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A genome-wide screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation [preprint], Michael C. Kiritsy, Michigan State University, Michigan State University, Michigan State University, Audrey E. Lord, M. Pontus A. Orning, Roland Elling, Katherine A. Fitzgerald, and Michigan State University

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Screening for Unhealthy Drug Use: US Preventive Services Task Force Recommendation Statement, Alex H. Krist, Karina W. Davidson, Carol M. Mangione, Michael J. Barry, Michael Cabana, Aaron B. Caughey, Susan J. Curry, Katrina Donahue, Chyke A. Doubeni, John W. Epling Jr, Martha Kubik, Gbenga Ogedegbe, Lori Pbert, Michael Silverstein, Melissa A. Simon, Chien-Wen Tseng, and John B. Wong

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Primary Care-Based Interventions to Prevent Illicit Drug Use in Children, Adolescents, and Young Adults: US Preventive Services Task Force Recommendation Statement, Alex H. Krist, Karina W. Davidson, Carol M. Mangione, Michael J. Barry, Michael Cabana, Aaron B. Caughey, Katrina Donahue, Chyke A. Doubeni, John W. Epling Jr., Martha Kubik, Gbenga Ogedegbe, Lori Pbert, Michael Silverstein, Melissa A. Simon, Chien-Wen Tseng, and John B. Wong

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Behavioral Counseling Interventions to Prevent Sexually Transmitted Infections: US Preventive Services Task Force Recommendation Statement, Alex H. Krist and Lori Pbert

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Separation and identification of permethylated glycan isomers by reversed phase nanoLC-NSI-MSn [preprint], Simone Kurz, M. Osman Sheikh, Shan Lu, Lance Wells, and Michael Tiemeyer

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Transgenic goats producing an improved version of cetuximab in milk [preprint], Götz Laible, Sally Cole, Brigid Brophy, Paul Maclean, Li How Chen, Dan P. Pollock, Lisa A. Cavacini, Nathalie Fournier, Christophe De Romeuf, Nicholas C. Masiello, William G. Gavin, David N. Wells, and Harry M. Meade

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An improved zebrafish transcriptome annotation for sensitive and comprehensive detection of cell type-specific genes, Nathan D. Lawson, Rui Li, Masahiro Shin, Ann S. Grosse, Onur Yukselen, Oliver A. Stone, Alper Kucukural, and Lihua Julie Zhu

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Deciphering complex mechanisms of resistance and loss of potency through coupled molecular dynamics and machine learning [preprint], Florian Leidner, Nese Kurt Yilmaz, and Celia A. Schiffer

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Reduced Neurog3 Gene Dosage Shifts Enteroendocrine Progenitor Toward Goblet Cell Lineage in the Mouse Intestine, Joyce H. Li, Subir Ray, Alper Kucukural, Gerard Gradwohl, and Andrew B. Leiter

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Vaping-Associated Respiratory Distress Syndrome: Case Classification and Clinical Guidance, Craig M. Lilly, Shahzad Khan, Kathryn Waksmundzki-Silva, and Richard S. Irwin

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Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes [preprint], Zongtao Lin, Xie Wang, Katelyn A. Bustin, Lin He, Radu M. Suciu, Nancy Schek, Mina Ahmadi, Kai Hu, Erika J. Olson, William H. Parsons, Eric S. Witze, Paul D. Morton, Ann M. Gregus, Matthew W. Buczynski, and Megan L. Matthews

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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale, Xihao Li, Jill E. Moore, Zhiping Weng, and Xihong Lin

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Optimizing the refinement of merohedrally twinned P61 HIV-1 protease-inhibitor cocrystal structures, Gordon J. Lockbaum, Florian Leidner, William E. Royer, Nese Kurt Yilmaz, and Celia A. Schiffer

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Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1, Heather S. Loring, Janneke D. Icso, Venkatesh V. Nemmara, and Paul R. Thompson

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Identification of the first noncompetitive SARM1 inhibitors, Heather S. Loring, Sangram Parelkar, Santanu Mondal, and Paul R. Thompson

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Emergence of SARM1 as a Potential Therapeutic Target for Wallerian-type Diseases, Heather S. Loring and Paul R. Thompson

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Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM [preprint], Anna B. Loveland, Egor Svidritskiy, Denis Susorov, Soojin Lee, Alexander Park, Gabriel Demo, Fen-Biao Gao, and Andrei A. Korostelev

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The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines [preprint], Jeremy Luban, Caterina Strambio De Castilla, Yetao Wang, Allan Jacobson, and Stuart Peltz

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Risk of Transmission of infection to Healthcare Workers delivering Supportive Care for Coronavirus Pneumonia; A Rapid GRADE Review [preprint], T.K. Luqman-Arafath, Sandeep Jubbal, Elakkat D. Gireesh, Jyothi Margapuri, Hanumantha Rao Jogu, Hitesh Patni, Tyler Thompson, Suma Menon, Arsh Patel, Amirahwaty Abdulla, and Sudheer Penupolu

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Neural activations during self-related processing in patients with chronic pain and effects of a brief self-compassion training - A pilot study, Jacqueline Lutz, Michael P. Berry, Vitaly Napadow, Christopher Germer, Susan Pollak, Paula Gardiner, Robert R. Edwards, Gaelle Desbordes, and Zev Schuman-Olivier

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Seroprevalence of SARS-CoV-2-Specific IgG Antibodies Among Adults Living in Connecticut Between March 1 and June 1, 2020: Post-Infection Prevalence (PIP) Study [preprint], Shiwani Mahajan, Lokinendi V. Rao, and Harlan M. Krumholz

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Seroprevalence of SARS-CoV-2-Specific IgG Antibodies Among Adults Living in Connecticut: Post-Infection Prevalence (PIP) Study [preprint], Shiwani Mahajan, Lokinendi V. Rao, and Harlan M. Krumholz

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Performance of Abbott Architect, Ortho Vitros, and Euroimmun Assays in Detecting Prior SARS-CoV-2 Infection [preprint], Shiwani Mahajan, Carrie A. Redlich, Adam V. Wisnewski, Louis E. Fazen, Lokinendi V. Rao, Karthik Kuppusamy, Albert I. Ko, and Harlan M. Krumholz

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JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma, Elisa Manieri, Tamera Barrett, Julie Cavanagh-Kyros, Roger J. Davis, Alfonso Mora, and Guadalupe Sabio

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Scalable learning of interpretable rules for the dynamic microbiome domain [preprint], Venkata Suhas Maringanti, Vanni Bucci, and Georg K. Gerber

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Methods for detecting PER2::LUCIFERASE bioluminescence rhythms in freely moving mice [preprint], B. Martin-Burgos, W. Wang, I. William, S. Tir, I. Mohammad, R. Javed, Smith College, Y. Cui, Ciearra B. Smith, V. van der Vinne, P.C. Molyneux, Stephen C. Miller, David R. Weaver, T.L. Leise, and M.E. Harrington

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Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors, Ashley N. Matthew, Jacqueto Zephyr, Nageswara Rao Desaboini, Mina Henes, Wasih Kamran, Klajdi Kosovrasti, Adam Hedger, Gordon J. Lockbaum, Jennifer Timm, Akbar Ali, Nese Kurt Yilmaz, and Celia A. Schiffer

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Optimization of Endovascular Therapy in the Neuroangiography Suite to Achieve Fast and Complete (Expanded Treatment in Cerebral Ischemia 2c-3) Reperfusion, Ryan A. McTaggart, Johanna M. Ospel, Marios-Nikos Psychogios, Ajit S. Puri, Christian Maegerlein, Kendall M. Lane, Mahesh V. Jayaraman, and Mayank Goyal

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Food Habits, Stressors, and Use of Complementary Medicine Therapies Among Pediatric Patients Who Attend an Integrative Medicine Pediatric Pain Clinic, Vidhita Mehta, Salvatore D'Amico, Man Luo, Kristen Bodner, Laura Goldstein, Caitlin Neri, and Paula Gardiner

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Patterns of heart Injury in COVID-19 and relation to outcome, Ajay Kumar Mishra, Kamal Kant Sahu, Amos Lal, and Jennifer B. Sargent

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A Developmental Analysis of Juxtavascular Microglia Dynamics and Interactions with the Vasculature, Erica Mondo, Shannon C. Becker, Amanda G. Kautzman, Martina Schifferer, Christina E. Baer, Jiapei Chen, Eric J. Huang, Mikael Simons, and Dorothy P. Schafer

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A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature [preprint], Erica Mondo, Shannon C. Becker, Amanda G. Kautzman, Martina Schifferer, Christina E. Baer, Jiapei Chen, Eric J. Huang, Mikael Simons, and Dorothy P. Schafer

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IgA MAb blocks SARS-CoV-2 Spike-ACE2 interaction providing mucosal immunity [preprint], Ejemel Monir, Qi Li, Shurong Hou, Zachary Schiller, Aaron Wallace, Alla Amcheslavsky, Nese Kurt Yilmaz, Jacqueline R. Toomey, Ryan Schneider, Lisa Cavacini, Mark S. Klempner, Celia A. Schiffer, and Yan Wang

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Differences in Staff-Assessed Pain Behaviors among Newly Admitted Nursing Home Residents by Level of Cognitive Impairment, Reynolds A. Morrison, William M. Jesdale, Catherine E. Dube, Anthony P. Nunes, Carol A. Bova, Shao-Hsien Liu, and Kate L. Lapane

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Chromosome-scale assembly of the coral endosymbiont Symbiodinium microadriaticum genome provides insight into the unique biology of dinoflagellate chromosomes [preprint], Ankita Nand, Ye Zhan, Octavio R. Salazar, Manuel Aranda, Christian R. Voolstra, and Job Dekker

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Social Media Utilization Among Shoulder and Elbow Surgeons, Ankur S. Narain, Arjun Dhayalan, Maxwell Weinberg, Luke D. Latario, Matthew E. Shuman, Jugert Bango, Sara Holmes, Jay K. Patel, Wayne Chan, and Daniel Aaron

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The Repair of an Acute Pathological Subtrochanteric Femur Fracture Using an Adult 3.5-mm Proximal Humerus Locking Plate in an Adolescent Patient: A Case Report, Alex Newbury, Philip Aurigemma, Mark T. Kraus, and Mathew J. Most

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Mycobacterium tuberculosis evasion of Guanylate Binding Protein-mediated host defense in mice requires the ESX1 secretion system [preprint], Andrew J. Olive, Clare M. Smith, Christina E. Baer, Jörn Coers, and Christopher M. Sassetti

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Detecting chromatin interactions along and between sister chromatids with SisterC [preprint], Marlies E. Oomen, Adam K. Hedger, Jonathan K. Watts, and Job Dekker

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Regulation of the Mammalian SWI/SNF Family of Chromatin Remodeling Enzymes by Phosphorylation during Myogenesis, Teresita Padilla-Benavides, Pablo Reyes-Gutierrez, and Anthony N. Imbalzano

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Atomistic Mechanism of Force Generation, Translocation, and Coordination in a Viral Genome Packaging Motor [preprint], Joshua Pajak, Erik Dill, Mark A. White, Brian A. Kelch, Paul Jardine, Gaurav Arya, and Marc C. Morais

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The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility, Pei-Hsuan Wu, Yu Fu, Katharine Cecchini, Deniz M. Ozata, Amena Arif, Tianxiong Yu, Cansu Colpan, Ildar Gainetdinov, Zhiping Weng, and Phillip D. Zamore

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LogoJS: a Javascript package for creating sequence logos and embedding them in web applications, Henry E. Pratt and Zhiping Weng

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An in-depth investigation of the safety and immunogenicity of an inactivated SARS-CoV-2 vaccine [preprint], Jing Pu, Shan Lu, and Qihan Li

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A Comparison of Non-Invasive Blood Pressure Measurement Strategies with Intra-Arterial Measurement, Matthew Rebesco, M. Cornelia Pinkston, Nicholas A. Smyrnios, and Stacy N. Weisberg

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Drug antagonism and single-agent dominance result from differences in death kinetics, Ryan Richards, Hannah R. Schwartz, Megan E. Honeywell, Mariah S. Stewart, Peter Cruz-Gordillo, Anna J. Joyce, Benjamin D. Landry, and Michael J. Lee

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An atlas of cell types in the mammalian epididymis and vas deferens [preprint], Vera D. Rinaldi, Elisa Donnard, Kyle Gellatly, Morten Rasmussen, Alper Kucukural, Onur Yukselen, Manuel Garber, Upasna Sharma, and Oliver J. Rando

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An atlas of cell types in the mouse epididymis and vas deferens, Vera D. Rinaldi, Elisa Donnard, Kyle Gellatly, Morten Rasmussen, Alper Kucukural, Onur Yukselen, Manuel Garber, Upasna Sharma, and Oliver J. Rando

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SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC [preprint], Christian F. Ruiz, Emily D. Montal, John A. Haley, and John D. Haley

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Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-Tetrahydrofuran in a Pseudo-Symmetric Dipeptide Isostere, Linah Rusere, Gordon J. Lockbaum, Mina Henes, Sook-Kyung Lee, Ean Spielvogel, Desaboini Nageswara Rao, Klajdi Kosovrasti, Ellen A. Nalivaika, Ronald Swanstrom, Nese Kurt Yilmaz, Celia A. Schiffer, and Akbar Ali

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PFRED: A computational platform for siRNA and antisense oligonucleotides design [preprint], Simone Sciabola, Hualin Xi, Dario Cruz, Qing Cao, Christine Lawrence, Tianhong Zhang, Sergio Rotstein, Jason D. Hughes, Daniel R. Caffrey, and Robert Stanton

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SARS-Coronavirus-2 nucleocapsid protein measured in blood using a Simoa ultra-sensitive immunoassay differentiates COVID-19 infection with high clinical sensitivity. [preprint], Dandan Shan, Eicke Latz, and Andrew J. Ball

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UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import [preprint], Tomer Shpilka, Yunguang Du, Qiyuan Yang, Andrew Melber, Nandhitha Uma Naresh, Joshua Lavelle, Pengpeng Liu, Hilla Weidberg, Rui Li, Jun Yu, Lihua Julie Zhu, Lara Strittmatter, and Cole M. Haynes

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FMRP Links Optimal Codons to mRNA stability in Neurons [preprint], Huan Shu, Elisa Donnard, Botao Liu, Ruijia Wang, and Joel D. Richter