UMMS Affiliation
Department of Medicine, Division of Dermatology
Publication Date
4-25-2013
Document Type
Article
Subjects
Amines; Antidepressive Agents, Tricyclic; Behavior Therapy; Chronic Disease; Cyclohexanecarboxylic Acids; Emollients; Excitatory Amino Acid Antagonists; Histamine Antagonists; Humans; Male; Mianserin; Middle Aged; Pruritus; gamma-Aminobutyric Acid
Disciplines
Dermatology | Skin and Connective Tissue Diseases
Abstract
This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations. Case: An otherwise healthy 55-year-old man reports that he has been itchy all over for 6 months. The itch interferes with falling asleep and wakes him repeatedly during the night. Initially, there was no rash, but during the past 4 months, itchy nodules and plaques have developed on his back, arms, and legs. Treatment with sedating and nonsedating oral antihistamines and topical glucocorticoids has had no effect. How would you evaluate and manage this case?
Rights and Permissions
Publisher PDF posted as allowed by the publisher's author rights policy at http://www.nejm.org/page/author-center/permissions.
DOI of Published Version
10.1056/NEJMcp1208814
Source
N Engl J Med. 2013 Apr 25;368(17):1625-34. doi: 10.1056/NEJMcp1208814. Link to article on publisher's site
Journal/Book/Conference Title
The New England journal of medicine
Related Resources
PubMed ID
23614588
Repository Citation
Yosipovitch, Gil and Bernhard, Jeffrey D., "Clinical practice. Chronic pruritus" (2013). Dermatology Publications and Presentations. 75.
https://escholarship.umassmed.edu/derm_pubs/75