Title

Loose anagen hair syndrome in two patients with epidermolysis bullosa simplex, Dowling-Meara type

UMMS Affiliation

Department of Medicine, Division of Dermatology; Department of Cancer Biology; Department of Pediatrics

Publication Date

2012-9

Document Type

Letter to the Editor

Subjects

Child; Child, Preschool; Comorbidity; Epidermolysis Bullosa Simplex; Female; Humans; Keratin-14; Loose Anagen Hair Syndrome; Mutation

Disciplines

Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Dermatology | Genetic Phenomena | Pathological Conditions, Signs and Symptoms | Pathology | Pediatrics | Skin and Connective Tissue Diseases

Abstract

To the Editor: We describe two patients with epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM), who also have loose anagen hair syndrome (LAHS). EBS-DM is a severe form of EBS marked by widespread herpetiform blistering, worse during infancy.1 LAHS is diagnosed by the ability to painlessly extract anagen hairs from the scalp that lack an external root sheath and demonstrate cuticle ruffling distal to a misshapen bulb.2 The hair is typically sparse and seldom requires cutting.2 An association between these entities has not previously been reported, to our knowledge.

DOI of Published Version

10.1016/j.jaad.2011.10.013

Source

J Am Acad Dermatol. 2012 Sep;67(3):e120-1. doi: 10.1016/j.jaad.2011.10.013. Link to article on publisher's site

Journal/Book/Conference Title

Journal of the American Academy of Dermatology

Related Resources

Link to Article in PubMed

PubMed ID

22890742

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