Title
Loose anagen hair syndrome in two patients with epidermolysis bullosa simplex, Dowling-Meara type
UMMS Affiliation
Department of Medicine, Division of Dermatology; Department of Cancer Biology; Department of Pediatrics
Publication Date
2012-9
Document Type
Letter to the Editor
Subjects
Child; Child, Preschool; Comorbidity; Epidermolysis Bullosa Simplex; Female; Humans; Keratin-14; Loose Anagen Hair Syndrome; Mutation
Disciplines
Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Dermatology | Genetic Phenomena | Pathological Conditions, Signs and Symptoms | Pathology | Pediatrics | Skin and Connective Tissue Diseases
Abstract
To the Editor: We describe two patients with epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM), who also have loose anagen hair syndrome (LAHS). EBS-DM is a severe form of EBS marked by widespread herpetiform blistering, worse during infancy.1 LAHS is diagnosed by the ability to painlessly extract anagen hairs from the scalp that lack an external root sheath and demonstrate cuticle ruffling distal to a misshapen bulb.2 The hair is typically sparse and seldom requires cutting.2 An association between these entities has not previously been reported, to our knowledge.
DOI of Published Version
10.1016/j.jaad.2011.10.013
Source
J Am Acad Dermatol. 2012 Sep;67(3):e120-1. doi: 10.1016/j.jaad.2011.10.013. Link to article on publisher's site
Journal/Book/Conference Title
Journal of the American Academy of Dermatology
Related Resources
PubMed ID
22890742
Repository Citation
Crombie J, Greenlaw SM, Fenner J, Lyle S, Wiss K. (2012). Loose anagen hair syndrome in two patients with epidermolysis bullosa simplex, Dowling-Meara type. Dermatology Publications. https://doi.org/10.1016/j.jaad.2011.10.013. Retrieved from https://escholarship.umassmed.edu/derm_pubs/52