Failed treatment of amelanotic lentigo maligna with imiquimod followed by pigment production
Department of Medicine, Division of Dermatology
Letter to the Editor
Medical Subject Headings
Administration, Topical; Aminoquinolines; Biopsy, Needle; Female; Follow-Up Studies; Humans; Hutchinson's Melanotic Freckle; Immunohistochemistry; Melanoma, Amelanotic; Middle Aged; Neoplasm Recurrence, Local; Nose; Risk Assessment; Skin Neoplasms; Treatment Outcome
Dermatology | Skin and Connective Tissue Diseases
A melanotic lentigo maligna (ALM) represents a small subset of lentigo maligna (LM) that lacks pigment. At least 2 cases of ALM responsive to imiquimod therapy with short-term follow-up have been reported. We report herein a case of ALM that failed to respond to imiquimod treatment. Furthermore, after therapy was initiated, the ALM began to produce pigment and transformed to LM.
Martires, Kathryn J.; Capaldi, Laura; Pattee, Sean F.; Maloney, Mary E.; and Bordeaux, Jeremy S., "Failed treatment of amelanotic lentigo maligna with imiquimod followed by pigment production" (2010). Dermatology Publications and Presentations. 30.