Febrile ulceronecrotic Mucha-Habermann's disease

Bruce L. Warshauer, Dartmouth-Hitchcock Medical Center
Mary E. Maloney, University of Massachusetts Medical School
Robert L. Dimond, Veterans Administration Medical Center

At the time of publication, Mary E. Maloney was not yet affiliated with the University of Massachusetts Medical School.


A patient with febrile ulceronecrotic Mucha-Habermann's disease manifested the characteristic features of this entity. These include a polymorphous eruption with histopathologic findings of Mucha-Habermann's disease, large ulceronecrotic skin lesions, intermittent high fever, and constitutional symptoms. The patient was unique in that he also had malabsorption and eosinophilia. This disease may represent a hypersensitivity reaction. To our knowledge, there are five previous cases of febrile ulceronecrotic Mucha-Habermann's disease reported in the world literature.