Title

COVID-19 Pandemic and Burden of Non-Communicable Diseases: An Ecological Study on Data of 185 Countries

UMMS Affiliation

Department of Neurology

Publication Date

2020-09-01

Document Type

Article

Disciplines

Cardiovascular Diseases | Clinical Epidemiology | Epidemiology | Health Services Research | Infectious Disease | International Public Health | Virus Diseases

Abstract

Background: The interaction between coronavirus disease 2019 (COVID-19) and non-communicable diseases may increase the global burden of disease. We assessed the association of COVID-19 with ageing and non-communicable diseases.

Methods: We extracted data regarding non-communicable disease, particularly cardiovascular disease, deaths, disability-adjusted life years (DALYs), and healthy life expectancy (HALE) from the Global Burden of Disease Study (GBD) 2017. We obtained data of confirmed COVID-19 cases, deaths, and tests from the Our World in Data database as of May 28, 2020. Potential confounders of pandemic outcomes analyzed include institutional lockdown delay, hemispheric geographical location, and number of tourists. We compared all countries according to GBD classification and World Bank income level. We assessed the correlation between independent variables associated with COVID-19 caseload and mortality using Spearman's rank correlation and adjusted mixed model analysis.

Findings: High-income had the highest, and the Southeast Asia, East Asia, and Oceania region had the least cases per million population (3050.60 vs. 63.86). Sub-saharan region has reported the lowest number of COVID-19 mortality (1.9). Median delay to lockdown initiation varied from one day following the first case in Latin America and Caribbean region, to 34 days in Southeast Asia, East Asia, and Oceania. Globally, non-communicable disease DALYs were correlated with COVID-19 cases (r = 0.32, p< 0.001) and deaths (r = 0.37, p< 0.001). HALE correlated with COVID-19 cases (r = 0.63, p< .001) and deaths (r = 0.61, p< 0.001). HALE was independently associated with COVID-19 case rate and the number of tourists was associated with COVID-19 mortality in the adjusted model.

Interpretation: Preventive measures against COVID-19 should protect the public from the dual burden of communicable and non-communicable diseases, particularly in the elderly. In addition to active COVID-19 surveillance, policymakers should utilize this evidence as a guide for prevention and coordination of health services. This model is timely, as many countries have begun to reduce social isolation.

Keywords

Coronavirus, COVID-19, Stroke, Prevention, Correlation, Mortality, Incidence

DOI of Published Version

10.1016/j.jstrokecerebrovasdis.2020.105089

Source

Azarpazhooh MR, Morovatdar N, Avan A, Phan TG, Divani AA, Yassi N, Stranges S, Silver B, Biller J, Tokazebani Belasi M, Kazemi Neya S, Khorram B, Frydman A, Nilanont Y, Onorati E, Di Napoli M. COVID-19 Pandemic and Burden of Non-Communicable Diseases: An Ecological Study on Data of 185 Countries. J Stroke Cerebrovasc Dis. 2020 Sep;29(9):105089. doi: 10.1016/j.jstrokecerebrovasdis.2020.105089. Epub 2020 Jun 25. PMID: 32807484; PMCID: PMC7315949. Link to article on publisher's site

Journal/Book/Conference Title

Journal of Stroke and Cerebrovascular Diseases

Comments

Full author list omitted for brevity. For the full list of authors, see article.

Related Resources

Link to article in PubMed

PubMed ID

32807484

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