UMMS Affiliation

Department of Medicine, Division of Hospital Medicine

Publication Date

2020-06-10

Document Type

Article

Disciplines

Cardiology | Cardiovascular Diseases | Infectious Disease | Nervous System Diseases | Neurology | Virus Diseases

Abstract

Neurological manifestations in patients with COVID-19 are more frequently being reported. Cerebrovascular events have been reported in around 3% of patients. In this review we summarize the published literature on cerebrovascular events in patients with COVID-19 as available on the PubMed database. So far, 3 studies have reported cerebrovascular events. Cerebrovascular events were identified on screening patients with decreased consciousness or in the presence of focal neurological deficits. These events were common in elderly, critically ill patients and in patients with prior cardio-cerebrovascular comorbidities. The diagnosis of cerebrovascular events was confirmed with computed tomography of the brain in most studies reporting neurological events. Multiple pathological mechanisms have been postulated regarding the process of neurological and vascular injury among which cytokine storm is shown to correlate with mortality. Patients with severe illness are found to have a higher cardio- cerebrovascular comorbidity. With an increasing number of cases and future prospective studies, the exact mechanism by which these cerebrovascular events occur and attribute to the poor outcome will be better understood.

Keywords

COVID-19, neurological manifestations, cerebrovascular events

Rights and Permissions

Copyright (c) 2020 The Author(s). This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

DOI of Published Version

10.4081/monaldi.2020.1341

Source

Mishra AK, Sahu KK, George AA, Sargent J, Lal A. Cerebrovascular events in COVID-19 patients. Monaldi Arch Chest Dis. 2020 Jun 10;90(2). doi: 10.4081/monaldi.2020.1341. PMID: 32527073. Link to article on publisher's site

Journal/Book/Conference Title

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

Related Resources

Link to Article in PubMed

PubMed ID

32527073

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

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