Department of Medicine, Division of Cardiovascular Medicine
Cardiology | Cardiovascular Diseases | Fluids and Secretions | Immunology and Infectious Disease | Infectious Disease | Virus Diseases
For the past 150 years, platelets have been recognized as the major blood component that mediates hemostasis and thrombosis. In more recent years, however, we have come to appreciate that platelets also perform profound immune functions during infection with various pathogens. We now recognize that platelets can also mediate a response to various RNA viruses such as influenza and that many viral infections, including the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), can affect platelet count. Thrombocytopenia and increased coagulation have been independently associated with increased mortality. This article provides a perspective on the potential roles of platelets during COVID‐19.
platelets, COVID-19, SARS-CoV-2, immunity, thrombosis
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This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
DOI of Published Version
Koupenova M. Potential Role of Platelets in COVID‐19: Implications for Thrombosis. Res Pract Thromb Haemost. 2020 May 29:10.1002/rth2.12397. doi: 10.1002/rth2.12397. PMCID: PMC7283793. Link to article on publisher website
Research and Practice in Thrombosis and Haemostasis
Koupenova M. (2020). Potential Role of Platelets in COVID‐19: Implications for Thrombosis. COVID-19 Publications by UMMS Authors. https://doi.org/10.1002/rth2.12397. Retrieved from https://escholarship.umassmed.edu/covid19/50
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This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.