Title

Magnetic Resonance Imaging Alteration of the Brain in a Patient With Coronavirus Disease 2019 (COVID-19) and Anosmia

UMMS Affiliation

Department of Radiology; Advanced MRI Center

Publication Date

2020-05-29

Document Type

Article

Disciplines

Infectious Disease | Nervous System Diseases | Neurology | Radiology | Virus Diseases

Abstract

The neurotropism of human coronaviruses has already been demonstrated in small animals, and in autoptic studies the severe acute respiratory syndrome coronavirus (SARS-CoV), which was responsible for the SARS outbreak during 2002 to 2003, was found in the brains of patients with infection. It has been proposed that the neuroinvasive potential of the novel SARS-CoV-2, responsible for coronavirus disease 2019 (COVID-19), may be at least partially responsible for the respiratory failure of patients with COVID-19.2 In this article, we share the magnetic resonance imaging (MRI) evidence of in vivo brain alteration presumably due to SARS-CoV-2 and demonstrate that anosmia can represent the predominant symptom in COVID-19.

Keywords

neuroradiology, images, magnetic resonance imaging, infectious diseases, coronavirus, COVID-19, anosmia

DOI of Published Version

10.1001/jamaneurol.2020.2125

Source

Politi LS, Salsano E, Grimaldi M. Magnetic Resonance Imaging Alteration of the Brain in a Patient With Coronavirus Disease 2019 (COVID-19) and Anosmia. JAMA Neurol. 2020 May 29. doi: 10.1001/jamaneurol.2020.2125. Epub ahead of print. PMID: 32469400. Link to article on publisher's site

Journal/Book/Conference Title

JAMA neurology

Related Resources

Link to Article in PubMed

PubMed ID

32469400

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