Magnetic Resonance Imaging Alteration of the Brain in a Patient With Coronavirus Disease 2019 (COVID-19) and Anosmia
Department of Radiology; Advanced MRI Center
Infectious Disease | Nervous System Diseases | Neurology | Radiology | Virus Diseases
The neurotropism of human coronaviruses has already been demonstrated in small animals, and in autoptic studies the severe acute respiratory syndrome coronavirus (SARS-CoV), which was responsible for the SARS outbreak during 2002 to 2003, was found in the brains of patients with infection. It has been proposed that the neuroinvasive potential of the novel SARS-CoV-2, responsible for coronavirus disease 2019 (COVID-19), may be at least partially responsible for the respiratory failure of patients with COVID-19.2 In this article, we share the magnetic resonance imaging (MRI) evidence of in vivo brain alteration presumably due to SARS-CoV-2 and demonstrate that anosmia can represent the predominant symptom in COVID-19.
neuroradiology, images, magnetic resonance imaging, infectious diseases, coronavirus, COVID-19, anosmia
DOI of Published Version
Politi LS, Salsano E, Grimaldi M. Magnetic Resonance Imaging Alteration of the Brain in a Patient With Coronavirus Disease 2019 (COVID-19) and Anosmia. JAMA Neurol. 2020 May 29. doi: 10.1001/jamaneurol.2020.2125. Epub ahead of print. PMID: 32469400. Link to article on publisher's site
Politi LS, Salsano E, Grimaldi M. (2020). Magnetic Resonance Imaging Alteration of the Brain in a Patient With Coronavirus Disease 2019 (COVID-19) and Anosmia. COVID-19 Publications by UMass Chan Authors. https://doi.org/10.1001/jamaneurol.2020.2125. Retrieved from https://escholarship.umassmed.edu/covid19/43