Title

Update Alert: Should Remdesivir Be Used for the Treatment of Patients With COVID-19? Rapid, Living Practice Points From the American College of Physicians (Version 2)

UMMS Affiliation

Department of Medicine

Publication Date

2021-09-01

Document Type

Article

Disciplines

Health Services Administration | Health Services Research | Infectious Disease | Internal Medicine | Patient Safety | Therapeutics | Virus Diseases

Abstract

This is an update of the American College of Physicians' living, rapid practice points about using remdesivir for treatment of COVID-19, which is based on an updated systematic review done through 10 May 2021. The evidence update identified 1 new study that could inform Practice Point 1. No new studies were identified as supporting evidence for Practice Points 2 or 3. The new study did not have an effect on our prior conclusions and resulted in no changes to the practice points (see the next section and the Supplement). We have changed the term mechanical ventilation to invasive ventilation to better reflect most of the patient populations informing the practice points. We define invasive ventilation as administering supplemental oxygen with positive pressure to the lungs via an endotracheal or tracheostomy tube. The Supplement summarizes the evidence, evidence gaps, and clinical considerations.

Keywords

remdesivir, hospitalized patients, coronavirus disease 2019, COVID-19, effectiveness, harms

DOI of Published Version

10.7326/L21-0389

Source

Qaseem A, Yost J, Etxeandia-Ikobaltzeta I, Abraham GM, Jokela JA, Miller MC, Forciea MA, Humphrey LL. Update Alert: Should Remdesivir Be Used for the Treatment of Patients With COVID-19? Rapid, Living Practice Points From the American College of Physicians (Version 2). Ann Intern Med. 2021 Sep;174(9):W66-W67. doi: 10.7326/L21-0389. Epub 2021 Jul 13. PMID: 34251904; PMCID: PMC8297419. Link to article on publisher's site

Journal/Book/Conference Title

Annals of internal medicine

Related Resources

Link to Article in PubMed

PubMed ID

34251904

Share

COinS