A Splenic Infarction Related to Parainfluenza Infection in a Patient with AML: Lessons for COVID-19
Department of Medicine, Division of Hematology Oncology; School of Medicine
Cardiovascular Diseases | Hemic and Lymphatic Diseases | Infectious Disease | Pathological Conditions, Signs and Symptoms | Virus Diseases
Infection related thrombosis is a well-known entity. Antigen burden, immune response, complement activation, pro-coagulant condition, and smoking are only a few amongst the multiple risk factors which interplay in the development of thrombosis in any given case. Viral infections are amongst the many inciting factors known to predispose a prothrombotic state. We hereby report a known case of acute myelogenous leukemia, status post allogeneic stem cell trans-plantation who presented with two discrete episodes of sore throat and left upper quadrant pain. Infectious workup confirmed parainfluenza virus 3 on the first occasion, and rhinovirus infection on the second occasion. Computed tomography of the abdomen during both times suggested a splenic infarction. A comprehensive thrombotic workup was negative which suggested the diagnosis of viral infection-related splenic infarction. This case highlights the importance of caring for the potential eventualities of coagulopathy in cancer and other immunocompromised patients infected during the COVID-19 pandemic.
DOI of Published Version
Sahu KK, E Vogt B, Shanahan L, Cerny J. A Splenic Infarction Related to Parainfluenza Infection in a Patient with AML: Lessons for COVID-19. Acta Biomed. 2021 Sep 2;92(4):e2021256. doi: 10.23750/abm.v92i4.11095. PMID: 34487090. Link to article on publisher's site
Acta bio-medica : Atenei Parmensis
Sahu KK, Vogt BE, Shanahan L, Cerny J. (2021). A Splenic Infarction Related to Parainfluenza Infection in a Patient with AML: Lessons for COVID-19. COVID-19 Publications by UMass Chan Authors. https://doi.org/10.23750/abm.v92i4.11095. Retrieved from https://escholarship.umassmed.edu/covid19/301