UMMS Affiliation

Department of Medicine, Division of Infectious Diseases and Immunology

Publication Date


Document Type

Article Postprint


Immunology of Infectious Disease | Immunoprophylaxis and Therapy | Immunotherapy | Infectious Disease | Microbiology | Surgical Procedures, Operative | Virus Diseases


Despite emerging data suggesting reduced antibody responses among SOT recipients following SARS-CoV-2 vaccine, critical unanswered questions remain. The clinical implications of the reduced humoral response need to be assessed through prospective studies. Studies are likewise needed to inform which vaccine dosing strategies result in improved immunity and if such approaches maximize protection against severe infection in the vulnerable transplant population.


SARS-CoV-2, COVID-19, vaccine, antibodies, antibody response

Rights and Permissions

This article is protected by copyright. All rights reserved. This is a PDF file of an accepted manuscript that has been accepted for publication and posted with a 12-month embargo as allowed by the publisher’s author rights policy at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.

DOI of Published Version



Ison MG, Blumberg E, Halasa N, Kaul D, Theodoropoulos NM, Wolfe CR. Antibodies, boosters and optimizing SARS-CoV-2 vaccine for transplantation: A call for more research. Am J Transplant. 2021 Jul 9. doi: 10.1111/ajt.16758. Epub ahead of print. PMID: 34241964. Link to article on publisher's site

Journal/Book/Conference Title

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Related Resources

Link to Article in PubMed

PubMed ID


Available for download on Saturday, July 09, 2022