UMMS Affiliation

UMass Center for Clinical and Translational Science, Center for Clinical Research

Publication Date

2020-02-14

Document Type

Article

Disciplines

Bioinformatics | Computational Biology | Genomics | Immunology and Infectious Disease | Infectious Disease | Structural Biology | Virology | Virus Diseases

Abstract

When a new pathogen that causes a global epidemic in humans, one key question is where it comes from. This is especially important for a zoonotic infectious disease that jumps from animals to humans. Knowing the origin of such a pathogen is critical to develop means to block further transmission and to develop vaccines. Discovery of the origin of a newly human pathogen is a sophisticated process that requires extensive and vigorous scientific validations and generally takes many years, such as the cases for HIV-1, SARS and MERS. Unfortunately, before the natural sources of new pathogens are clearly defined, conspiracy theories that the new pathogens are man-made often surface as the source. However, in all cases, such theories have been debunked in history.

Keywords

2019-nCoV, HIV-1, COVID-19, genome, origination

Rights and Permissions

Copyright © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor and Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI of Published Version

10.1080/22221751.2020.1727299

Source

Emerg Microbes Infect. 2020 Dec;9(1):378-381. doi: 10.1080/22221751.2020.1727299. Link to article on publisher's site

Journal/Book/Conference Title

Emerging microbes and infections

Related Resources

Link to Article in PubMed

PubMed ID

32056509

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

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