UMMS Affiliation
Center for Outcomes Research
Publication Date
2011-6
Document Type
Article
Subjects
Aged; Colombia; Female; Guideline Adherence; Hospitals; Humans; *Inpatients; Middle Aged; *Risk Assessment; Risk Factors; Venous Thromboembolism
Disciplines
Cardiovascular Diseases | Clinical Epidemiology | Epidemiology | Health Services Research | Therapeutics
Abstract
INTRODUCTION: More information is needed on the risk of venous thromboembolism in the hospital setting, and on patterns of use of thromboprophylaxis, as advocated in consensus guidelines.ENDORSE was an international study aimed at evaluating hospital venous thromboembolism prevention practices in medical and surgical patients.
OBJECTIVES: The risk of venous thromboembolism was evaluated along with the use of thromboprophylaxis in hospitalized medical and surgical subjects; these data were compared with the international sample from the ENDORSE study.
MATERIALS AND METHODS: Participating institutions in Colombia were selected arbitrarily. The medical charts for medical and surgical patients were evaluated randomly. The 2004 American College of Chest Physician guidelines were used to evaluate risk of venous thromboembolism and adherence to recommended thromboprophylaxis regimens.
RESULTS: The study included 761 subjects (218 surgical, 543 medical) located in five acute care hospitals; 49% of these subjects were considered at risk of venous thromboembolism (40% medical, 72% surgical), compared with 52% in the international sample. Prophylaxis use was higher in medical patients at risk (63.7%, n = 137) than in surgical patients (48.4%, n = 76; p = 0.01). Compared with the international sample, the use of prophylaxis in Colombia was greater in medical patients (63.7% vs. 39.5%, p = 0.003), but lower in surgical patients (48.4% vs. 58.5%, p = 0.02).
CONCLUSIONS: Participating Colombian centers treat patients at risk of venous thromboembolism similarly to other participant countries, but appropriate prophylaxis was prescribed more frequently to medical patients. Greater efforts are needed, both in Colombia and around the world, to improve rates of appropriate venous thromboembolism prophylaxis in at-risk subjects.
Keywords
venous thromboembolism/epidemiology, thrombosis/prevention & control, risk management, general surgery, drug prescriptions
DOI of Published Version
10.7705/biomedica.v31i2.304
Source
Biomedica. 2011 Jun;31(2):200-8. doi: 10.7705/biomedica.v31i2.304. Link to article on publisher's site
Journal/Book/Conference Title
Biomedica : revista del Instituto Nacional de Salud
Related Resources
PubMed ID
22159536
Repository Citation
Dennis RJ, Roa JH, Villadiego J, Mendez F, Vieda E, Restrepo H. (2011). [Venous thromboembolism prophylaxis in Colombian surgical and medical patients: results for Colombia of the ENDORSE study]. ENDORSE Publications. https://doi.org/10.7705/biomedica.v31i2.304. Retrieved from https://escholarship.umassmed.edu/cor_endorse/19
Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.
Included in
Cardiovascular Diseases Commons, Clinical Epidemiology Commons, Epidemiology Commons, Health Services Research Commons, Therapeutics Commons
Comments
Article is in Spanish with an abstract in English.