UMMS Affiliation

Center for Outcomes Research

Publication Date

2011-6

Document Type

Article

Subjects

Aged; Colombia; Female; Guideline Adherence; Hospitals; Humans; *Inpatients; Middle Aged; *Risk Assessment; Risk Factors; Venous Thromboembolism

Disciplines

Cardiovascular Diseases | Clinical Epidemiology | Epidemiology | Health Services Research | Therapeutics

Abstract

INTRODUCTION: More information is needed on the risk of venous thromboembolism in the hospital setting, and on patterns of use of thromboprophylaxis, as advocated in consensus guidelines.ENDORSE was an international study aimed at evaluating hospital venous thromboembolism prevention practices in medical and surgical patients.

OBJECTIVES: The risk of venous thromboembolism was evaluated along with the use of thromboprophylaxis in hospitalized medical and surgical subjects; these data were compared with the international sample from the ENDORSE study.

MATERIALS AND METHODS: Participating institutions in Colombia were selected arbitrarily. The medical charts for medical and surgical patients were evaluated randomly. The 2004 American College of Chest Physician guidelines were used to evaluate risk of venous thromboembolism and adherence to recommended thromboprophylaxis regimens.

RESULTS: The study included 761 subjects (218 surgical, 543 medical) located in five acute care hospitals; 49% of these subjects were considered at risk of venous thromboembolism (40% medical, 72% surgical), compared with 52% in the international sample. Prophylaxis use was higher in medical patients at risk (63.7%, n = 137) than in surgical patients (48.4%, n = 76; p = 0.01). Compared with the international sample, the use of prophylaxis in Colombia was greater in medical patients (63.7% vs. 39.5%, p = 0.003), but lower in surgical patients (48.4% vs. 58.5%, p = 0.02).

CONCLUSIONS: Participating Colombian centers treat patients at risk of venous thromboembolism similarly to other participant countries, but appropriate prophylaxis was prescribed more frequently to medical patients. Greater efforts are needed, both in Colombia and around the world, to improve rates of appropriate venous thromboembolism prophylaxis in at-risk subjects.

Keywords

venous thromboembolism/epidemiology, thrombosis/prevention & control, risk management, general surgery, drug prescriptions

DOI of Published Version

10.7705/biomedica.v31i2.304

Source

Biomedica. 2011 Jun;31(2):200-8. doi: 10.7705/biomedica.v31i2.304. Link to article on publisher's site

Journal/Book/Conference Title

Biomedica : revista del Instituto Nacional de Salud

Comments

Article is in Spanish with an abstract in English.

Related Resources

Link to Article in PubMed

PubMed ID

22159536

Creative Commons License

Creative Commons Attribution 3.0 License
This work is licensed under a Creative Commons Attribution 3.0 License.

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