UMMS Affiliation

Department of Cell Biology

Publication Date


Document Type



Animals; Cell Lineage; Cell Nucleus; Cell Proliferation; *Epigenesis, Genetic; Humans; Mitosis; Transcription Factors


Cell Biology


Epigenetic control is required to maintain competency for the activation and suppression of genes during cell division. The association between regulatory proteins and target gene loci during mitosis is a parameter of the epigenetic control that sustains the transcriptional regulatory machinery that perpetuates gene-expression signatures in progeny cells. The mitotic retention of phenotypic regulatory factors with cell cycle, cell fate, and tissue-specific genes supports the coordinated control that governs the proliferation and differentiation of cell fate and lineage commitment.

Rights and Permissions

Copyright NRC Research Press.

DOI of Published Version



Biochem Cell Biol. 2009 Feb;87(1):1-6. Link to article on publisher's site

Journal/Book/Conference Title

Biochemistry and cell biology = Biochimie et biologie cellulaire

Related Resources

Link to Article in PubMed

PubMed ID


Included in

Cell Biology Commons



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