Cytoplasmic dynein nomenclature

UMMS Affiliation

Department of Cell Biology



Document Type



Animals; Cytoplasm; Dynein ATPase; Humans; *Terminology as Topic


A variety of names has been used in the literature for the subunits of cytoplasmic dynein complexes. Thus, there is a strong need for a more definitive consensus statement on nomenclature. This is especially important for mammalian cytoplasmic dyneins, many subunits of which are encoded by multiple genes. We propose names for the mammalian cytoplasmic dynein subunit genes and proteins that reflect the phylogenetic relationships of the genes and the published studies clarifying the functions of the polypeptides. This nomenclature recognizes the two distinct cytoplasmic dynein complexes and has the flexibility to accommodate the discovery of new subunits and isoforms.

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Citation: J Cell Biol. 2005 Nov 7;171(3):411-3. Epub 2005 Oct 31. Link to article on publisher's site

Related Resources

Link to Article in PubMed

Journal Title

The Journal of cell biology

PubMed ID