Cytoplasmic dynein nomenclature
Department of Cell Biology
Animals; Cytoplasm; Dynein ATPase; Humans; *Terminology as Topic
A variety of names has been used in the literature for the subunits of cytoplasmic dynein complexes. Thus, there is a strong need for a more definitive consensus statement on nomenclature. This is especially important for mammalian cytoplasmic dyneins, many subunits of which are encoded by multiple genes. We propose names for the mammalian cytoplasmic dynein subunit genes and proteins that reflect the phylogenetic relationships of the genes and the published studies clarifying the functions of the polypeptides. This nomenclature recognizes the two distinct cytoplasmic dynein complexes and has the flexibility to accommodate the discovery of new subunits and isoforms.
DOI of Published Version
J Cell Biol. 2005 Nov 7;171(3):411-3. Epub 2005 Oct 31. Link to article on publisher's site
The Journal of cell biology
Pfister, K. Kevin; Fisher, Elizabeth M. C.; Gibbons, Ian R.; Hays, Thomas S.; Holzbaur, Erika L. F.; McIntosh, J. Richard; Porter, Mary E.; Schroer, Trina A.; Vaughan, Kevin T.; Witman, George B.; King, Stephen M.; and Vallee, Richard B., "Cytoplasmic dynein nomenclature" (2005). Cell and Developmental Biology Publications. 33.