Title

Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus

UMMS Affiliation

Department of Cell and Developmental Biology; UMass Metabolic Network

Publication Date

7-20-2015

Document Type

Article

Disciplines

Biochemistry | Cell Biology | Molecular Biology

Abstract

The organization of interphase chromosomes in chromosome territories (CTs) was first proposed more than one hundred years ago. The introduction of increasingly sophisticated microscopic and molecular techniques, now provide complementary strategies for studying CTs in greater depth than ever before. Here we provide an overview of these strategies and how they are being used to elucidate CT interactions and the role of these dynamically regulated, nuclear-structure building blocks in directly supporting nuclear function in a physiologically responsive manner. This article is protected by copyright.

DOI of Published Version

10.1002/jcb.25280

Source

J Cell Biochem. 2015 Jul 20. doi: 10.1002/jcb.25280. Link to article on publisher's site.

Journal/Book/Conference Title

Journal of cellular biochemistry

Related Resources

Link to Article in PubMed

PubMed ID

26192137

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