Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus

UMMS Affiliation

Department of Cell and Developmental Biology; UMass Metabolic Network



Document Type



The organization of interphase chromosomes in chromosome territories (CTs) was first proposed more than one hundred years ago. The introduction of increasingly sophisticated microscopic and molecular techniques, now provide complementary strategies for studying CTs in greater depth than ever before. Here we provide an overview of these strategies and how they are being used to elucidate CT interactions and the role of these dynamically regulated, nuclear-structure building blocks in directly supporting nuclear function in a physiologically responsive manner. This article is protected by copyright.

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Citation: J Cell Biochem. 2015 Jul 20. doi: 10.1002/jcb.25280. Link to article on publisher's site.

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Link to Article in PubMed

Journal Title

Journal of cellular biochemistry

PubMed ID