The Dynamics of Morphogenesis in the Early Mouse Embryo
Department of Cell and Developmental Biology
Cell and Developmental Biology | Cell Biology | Developmental Biology
Over the past two decades, our understanding of mouse development from implantation to gastrulation has grown exponentially with an upsurge of genetic, molecular, cellular, and morphogenetic information. New discoveries have exalted the role of extraembryonic tissues in orchestrating embryonic patterning and axial specification. At the same time, the identification of unexpected morphogenetic processes occurring during mouse gastrulation has challenged established dogmas and brought new insights into the mechanisms driving germ layer formation. In this article, we summarize the key findings that have reinvigorated the contemporary view of early postimplantation mammalian development.
DOI of Published Version
Cold Spring Harb Perspect Biol. 2014 Jun 26. pii: a015867. doi: 10.1101/cshperspect.a015867. Link to article on publisher's site. [Epub ahead of print]
Cold Spring Harbor perspectives in biology
Rivera-Perez, Jaime A. and Hadjantonakis, Anna-Katerina, "The Dynamics of Morphogenesis in the Early Mouse Embryo" (2014). Cell and Developmental Biology Publications. 150.