Flipping a phosphate switch on kinesin-II to turn IFT around
Department of Cell and Developmental Biology
Animals; Calcium-Binding Proteins; Chlamydomonas reinhardtii; Flagella; *Gene Expression Regulation, Plant; Kinesin
Cilia and flagella are assembled and maintained by the motor-driven, bidirectional traffic of large protein complexes in a process termed intraflagellar transport (IFT). In this issue of Developmental Cell, Liang et al. (2014) report that IFT is regulated in part by the phosphorylation status of the kinesin-II subunit FLA8/KIF3B.
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Citation: Dev Cell. 2014 Sep 8;30(5):492-3. doi: 10.1016/j.devcel.2014.08.019. Link to article on publisher's site
Craige, Branch and Witman, George B., "Flipping a phosphate switch on kinesin-II to turn IFT around" (2014). Cell and Developmental Biology Publications. 146.