The Chlamydomonas genome project: a decade on
Department of Cell and Developmental Biology
The green alga Chlamydomonas reinhardtii is a popular unicellular organism for studying photosynthesis, cilia biogenesis, and micronutrient homeostasis. Ten years since its genome project was initiated an iterative process of improvements to the genome and gene predictions has propelled this organism to the forefront of the omics era. Housed at Phytozome, the plant genomics portal of the Joint Genome Institute (JGI), the most up-to-date genomic data include a genome arranged on chromosomes and high-quality gene models with alternative splice forms supported by an abundance of whole transcriptome sequencing (RNA-Seq) data. We present here the past, present, and future of Chlamydomonas genomics. Specifically, we detail progress on genome assembly and gene model refinement, discuss resources for gene annotations, functional predictions, and locus ID mapping between versions and, importantly, outline a standardized framework for naming genes.
DOI of Published Version
Trends Plant Sci. 2014 Oct;19(10):672-80. doi: 10.1016/j.tplants.2014.05.008. Link to article on publisher's site.
Trends in plant science
Blaby IK, Witman GB, Prochnik S. (2014). The Chlamydomonas genome project: a decade on. Cell and Developmental Biology Publications. https://doi.org/10.1016/j.tplants.2014.05.008. Retrieved from https://escholarship.umassmed.edu/cellbiology_pp/145