Seasonal variation of blood cholesterol levels: study methodology

UMMS Affiliation

Department of Medicine, Division of Preventive and Behavioral Medicine; Department of Medicine, Division of Cardiovascular Medicine



Document Type



Adult; Aged; Cholesterol; Cholesterol, Dietary; Exertion; Female; Humans; Hydrocortisone; Light; Male; Meteorological Factors; Middle Aged; Prospective Studies; Questionnaires; Random Allocation; *Research Design; *Seasons


Cardiology | Cardiovascular Diseases


This manuscript provides a description of the methodology used in the Seasonal Variation of Blood Cholesterol Levels (SEASON) study, with the intent of informing the scientific community of the available data sets and to invite a dialogue with scientists in complementary fields. The primary aim of the SEASON study is to describe and delineate the causes of seasonal variation of blood lipid levels in the general population. This research project is designed specifically to systematically collect and analyze a number of important variables necessary to study the role of seasonality in blood lipids and relevant covariates.

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Citation: J Biol Rhythms. 1999 Aug;14(4):330-9.

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