Acute myocardial infarction provoked by a cold pressor test

UMMS Affiliation

Department of Medicine, Division of Cardiovascular Medicine



Document Type



Angina Pectoris, Variant; Cold; Coronary Angiography; Coronary Vasospasm; Electrocardiography; Humans; Male; Middle Aged; Myocardial Infarction


Cardiology | Cardiovascular Diseases


Coronary artery spasm is a well documented cause of variant angina pectoris. It has also been postulated to cause acute myocardial infarction. The diagnosis of coronary artery spasm is frequently made by means of ergonovine provocation during cardiac catheterization. Spasm of the coronary arteries may also be provoked by the cold pressor test. We describe a patient in whom an acute myocardial infarction evolved after his chest pain was reproduced with a cold pressor test. We suggest that the cold pressor test should be performed with caution, and perhaps should be limited to the cardiac catheterization laboratory.

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Citation: Chest. 1981 Nov;80(5):649-51. Link to article on publisher's site

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