This collection showcases journal articles and other publications and presentations written by faculty and researchers of the Department of Medicine's Division of Cardiovascular Medicine.

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Publications from 2020

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Impact of comorbid conditions on disease-specific quality of life in older men and women with atrial fibrillation, Hawa O. Abu, Jane S. Saczynski, John E. Ware Jr., Jordy Mehawej, Tenes Paul, Hamza Awad, Benita A. Bamgbade, Isabelle C. Pierre-Louis, Mayra Tisminetzky, Catarina I. Kiefe, Robert J. Goldberg, and David D. McManus

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Multimorbidity, physical frailty, and self-rated health in older patients with atrial fibrillation, Hawa Ozien Abu, Jane Saczynski, Jordy Mehawej, Tenes Paul, Hamza Awad, Benita A. Bamgbade, Isabelle C. Pierre-Louis, Mayra Tisminetzky, Catarina I. Kiefe, Robert J. Goldberg, and David D. McManus

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Clinically Meaningful Change in Quality of Life and Associated Factors Among Older Patients With Atrial Fibrillation, Hawa Ozien Abu, Jane S. Saczynski, Jordy Mehawej, Mayra Tisminetzky, Catarina I. Kiefe, Robert J. Goldberg, and David D. McManus

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Comparative Safety and Effectiveness of Direct-Acting Oral Anticoagulants Versus Warfarin: a National Cohort Study of Nursing Home Residents, Matthew Alcusky, Jennifer Tjia, David D. McManus, Anne L. Hume, Marc Fisher, and Kate L. Lapane

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Psychosocial and cognitive multimorbidity and health-related quality of life and symptom burden in older adults with atrial fibrillation: The systematic assessment of geriatric elements in atrial fibrillation (SAGE-AF) cohort study, Benita A. Bamgbade, Saket Sanghai, David D. McManus, Darleen M. Lessard, Molly E. Waring, Sarah N. Forrester, Isabelle Pierre-Louis, and Jane S. Saczynski

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Association of subclinical atherosclerosis with echocardiographic indices of cardiac remodeling: The Framingham Study, Cecilia Castro-Diehl, Rebecca J. Song, Gary F. Mitchell, David D. McManus, Susan Cheng, Ramachandran S. Vasan, and Vanessa Xanthakis

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A Translational Model for Venous Thromboembolism: MicroRNA Expression in Hibernating Black Bears, Amanda Fazzalari, Giacomo Basadonna, Alper Kucukural, Kahraman Tanriverdi, Milka Koupenova-Zamor, Eric W. Dickson, Meghan Blackwood, Christian Mueller, Jane E. Freedman, and Mitchell A. Cahan

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Reduction in ST-Segment Elevation Cardiac Catheterization Laboratory Activations in the United States during COVID-19 Pandemic, Santiago Garcia, Mazen S. Albaghdadi, Perwaiz M. Meraj, Christian Schmidt, Ross Garberich, Farouc A. Jaffer, Simon Dixon, Jeffrey J. Rade, Mark Tannenbaum, Jenny Chambers, Paul P. Huang, and Timothy D. Henry

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Impact of COVID-19 pandemic on STEMI care: An expanded analysis from the United States, Santiago Garcia and Jeffrey J. Rade

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A case report of recurrent spontaneous coronary artery dissection and Takotsubo cardiomyopathy: a treatment dilemma, Hafiz U. Ghafoor, Abhishek Bose, Amr El-Meligy, and Joseph Hannan

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Premature Atrial and Ventricular Contraction Detection using Photoplethysmographic Data from a Smartwatch, Dong Han, Syed Khairul Bashar, Fahimeh Mohagheghian, Eric Y. Ding, Cody Whitcomb, David D. McManus, and Ki H. Chon

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Are We Optimizing the Use of Dual Antiplatelet Therapy in Patients Hospitalized with Acute Myocardial Infarction?, Essa Hariri, Darleen M. Lessard, Joel M. Gore, Jeffrey J. Rade, and Robert J. Goldberg

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Potential Role of Platelets in COVID‐19: Implications for Thrombosis, Milka Koupenova

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Platelets and COVID-19: Inflammation, Hyperactivation and Additional Questions, Milka Koupenova-Zamor and Jane E. Freedman

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Platelets and Immunity: Going Viral, Milka Koupenova-Zamor and Jane E. Freedman

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Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NADPH oxidase (NOX-2), Marin Kuntic, John F. Keaney Jr., and Thomas Munzel

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Perceived Efficacy in Patient-Physician Interactions among Older Adults with Atrial Fibrillation, Abraham Lin

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Changes in Glycemic Load Are Positively Associated with Small Changes in Primary Stress Markers of Allostatic Load in Puerto Rican Women, Andrea Lopez-Cepero, Milagros C. Rosal, Christine F. Frisard, Sharina D. Person, Ira S. Ockene, and Katherine L. Tucker

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Self-reported risk of stroke and factors associated with underestimation of stroke risk among older adults with atrial fibrillation: the SAGE-AF study, Jordy Mehawej, Jane S. Saczynski, Jerry H. Gurwitz, Hawa Ozien Abu, Benita A. Bamgbade, Weijia Wang, Tenes Paul, Katherine Trymbulak, Connor Saleeba, Zi-Yue Wang, Catarina I. Kiefe, Robert Goldberg, and David D. McManus

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Changing Trends in the Landscape of Patients Hospitalized With Acute Myocardial Infarction (2001 to 2011) (from the Worcester Heart Attack Study), Regino Mercado-Lubo, Jorge Yarzebski, Darleen M. Lessard, Joel M. Gore, and Robert J. Goldberg

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Histone deacetylases 1 and 2 silence cryptic transcription to promote mitochondrial function during cardiogenesis, Zachary J. Milstone, Sherin Saheera, Lauren Bourke, Tomer Shpilka, Cole M. Haynes, and Chinmay M. Trivedi

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Effects of tobacco cigarettes, e-cigarettes, and waterpipe smoking on endothelial function and clinical outcomes, Thomas Munzel, Omar Hahad, Marin Kuntic, John F. Keaney Jr., John E. Deanfield, and Andreas Daiber

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The Repair of an Acute Pathological Subtrochanteric Femur Fracture Using an Adult 3.5-mm Proximal Humerus Locking Plate in an Adolescent Patient: A Case Report, Alex Newbury, Philip Aurigemma, Mark T. Kraus, and Mathew J. Most

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Addressing decontaminated respirators: Some methods appear to damage mask integrity and protective function, Richard E. Peltier, Jiayuan Wang, Brian L. Hollenbeck, Jennifer Lanza, Ryan M. Furtado, Jay Cyr, Richard T. Ellison III, and Kimiyoshi J. Kobayashi

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Post myocardial infarction complications during the COVID-19 pandemic - A case series, Waqas Qureshi, Summer Aldrugh, Adedotun Ogunsua, Colleen Harrington, Wahaj Aman, Leora B. Balsam, Biswajit Kar, Gerard P. Aurigemma, Amartya Kundu, Nirmal Kaur, Craig Smith, Daniel Z. Fisher, Jeffrey J. Rade, and Nikolaos Kakouros

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Machine Learning Model Based on Transthoracic Bioimpedance and Heart Rate Variability for Lung Fluid Accumulation Detection: Prospective Clinical Study, Natasa Reljin, Hugo F. Posada-Quintero, Caitlin Eaton-Robb, Sophia Binici, Emily Ensom, Eric Y. Ding, Anna Hayes, Jarno Riistama, Chad E. Darling, David D. McManus, and Ki H. Chon

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Learning Latent Space Representations to Predict Patient Outcomes: Model Development and Validation, Subendhu Rongali, Adam J. Rose, David D. McManus, Adarsha Bajracharya, Alok Kapoor, Edgard A. Granillo, and Hong Yu

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Nano-Vesicle (Mis)Communication in Senescence-Related Pathologies, Sherin Saheera, Ajay Godwin Potnuri, and Prasanna Krishnamurthy

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Rates of Potentially Inappropriate Dosing of Direct-Acting Oral Anticoagulants and Associations With Geriatric Conditions Among Older Patients With Atrial Fibrillation: The SAGE-AF Study, Saket Sanghai, Cecillia Wong, Ziyue Wang, Pia Clive, Wenisa Tran, Molly Waring, Robert J. Goldberg, Robert Hayward, Jane S. Saczynski, and David D. McManus

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ACEing COVID-19: A Role For Angiotensin Axis Inhibition in SARS-CoV-2 infection, Ravi Shah, Milka Koupenova-Zamor, and Venkatesh L. Murthy

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SARS-CoV-2 and COVID-19: A genetic, epidemiological, and evolutionary perspective, Manuela Sironi, Seyed E. Hasnain, Tung Phan, Fabio Luciani, Marie-Anne Shaw, M. Anice Sallum, Marzieh Ezzaty Mirhashemi, Serge Morand, and Fernando Gonzalez-Candelas

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Association of Use of an Integrated Specialty Pharmacy With Total Medical Expenditures Among Members of an Accountable Care Organization, Apurv Soni, Brian S. Smith, Thomas Scornavacca, Bill McElnea, Alice Shakman, Eric W. Dickson, and David D. McManus

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Mobile health assessments of geriatric elements in older patients with atrial fibrillation: The Mobile SAGE-AF Study (M-SAGE), Katherine Trymbulak, Eric Y. Ding, Francesca Marino, and Zi-Yue Wang

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Relations between plasma microRNAs, echocardiographic markers of atrial remodeling, and atrial fibrillation: Data from the Framingham Offspring study, Aditya Vaze, Khanh-Van T. Tran, Kahraman Tanriverdi, Mayank Sardana, Darleen M. Lessard, J. Kevin Donahue, Bruce A. Barton, Gerard P. Aurigemma, Amiya Mandapati, Jane E. Freedman, and David D. McManus

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Hearing loss and cognitive decline among older adults with atrial fibrillation: the SAGE-AF study, Weijia Wang, Darleen M. Lessard, Hawa Ozien Abu, David D. McManus, Tanya Mailhot, Jerry H. Gurwitz, Robert Goldberg, and Jane Saczynski

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Incident frailty and cognitive impairment by heart failure status in older patients with atrial fibrillation: the SAGE-AF study, Weijia Wang, Darleen M. Lessard, Jane Saczynski, Robert J. Goldberg, Alan S. Go, Tenes Paul, Ely Gracia, and David D. McManus

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The Impact of COVID-19 on Cardiovascular Training Programs: Challenges, Responsibilities and Opportunities, Gaby Weissman, James A. Arrighi, Naomi F. Botkin, Julie B. Damp, Friederike K. Keating, Venu Menon, Lisa J. Rose-Jones, Harsimran S. Singh, Victor Soukoulis, and Andrew M. Kates

Publications from 2019

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TRACE-CORE Dataset on Religious Practices and Long-Term Survival after Hospital Discharge for an Acute Coronary Syndrome, Hawa O. Abu, Kate L. Lapane, Molly E. Waring, Christine M. Ulbricht, Randolph S. Devereaux, David D. McManus, Jeroan J. Allison, Catarina I. Kiefe, and Robert J. Goldberg

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Religious practices and long-term survival after hospital discharge for an acute coronary syndrome, Hawa Ozien Abu, Kate L. Lapane, Molly E. Waring, Christine M. Ulbricht, Randolph S. Devereaux, David D. McManus, Jeroan J. Allison, Catarina I. Kiefe, and Robert J. Goldberg

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Religiosity and Patient Activation Among Hospital Survivors of an Acute Coronary Syndrome, Hawa Ozien Abu, David D. McManus, Catarina I. Kiefe, and Robert J. Goldberg

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Religious practices and changes in health-related quality of life after hospital discharge for an acute coronary syndrome, Hawa Ozien Abu, David D. McManus, Darleen M. Lessard, Catarina I. Kiefe, and Robert J. Goldberg

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Changes in Anticoagulant Utilization Among United States Nursing Home Residents With Atrial Fibrillation From 2011 to 2016, Matthew Alcusky, David D. McManus, Anne L. Hume, Marc Fisher, Jennifer Tjia, and Kate L. Lapane

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Atrial Fibrillation Detection from Wrist Photoplethysmography Signals Using Smartwatches, Syed Khairul Bashar, Dong Han, Shirin Hajeb-Mohammadalipour, Eric Y. Ding, Cody Whitcomb, David D. McManus, and Ki H. Chon

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VERB: VFCDM-Based Electrocardiogram Reconstruction and Beat Detection Algorithm, Syed Khairul Bashar, Allan J. Walkey, David D. McManus, and Ki H. Chon

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Evaluation of prophylactic dosages of Enoxaparin in non-surgical elderly patients with renal impairment, Nibal Chamoun, Hady Ghanem, Ahmad Hachem, Essa Hariri, Christelle Lteif, Hanine Mansour, Hani Dimassi, Richard Zalloum, and Georges Ghanem

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JNK and cardiometabolic dysfunction, Siobhan M. Craige, Kai Chen, Robert M. Blanton, John F. Keaney Jr., and Shashi Kant

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Point-of-care technologies in heart, lung, blood and sleep disorders from the Center for Advancing Point-of-Care Technologies, Eric Y. Ding, Emily Ensom, Nathaniel Hafer, Bryan Buchholz, Mary Ann Picard, Denise Dunlap, Eugene Rogers, Carl Lawton, Ainat Koren, Craig M. Lilly, Timothy P. Fitzgibbons, and David D. McManus

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Accuracy and Usability of a Novel Algorithm for Detection of Irregular Pulse Using a Smartwatch Among Older Adults: Observational Study, Eric Y. Ding, Dong Han, Cody Whitcomb, Syed Khairul Bashar, Oluwaseun Adaramola, Apurv Soni, Jane Saczynski, Timothy P. Fitzgibbons, Majaz Moonis, Steven A. Lubitz, Darleen M. Lessard, Mellanie True Hills, Bruce A. Barton, Ki Chon, and David D. McManus

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Coronary disease is not associated with robust alterations in inflammatory gene expression in human epicardial fat, Timothy P. Fitzgibbons, Nancy Lee, Khanh-Van T. Tran, Sarah M. Nicoloro, Mark Kelly, Stanley Kc Tam, and Michael P. Czech

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Wake Forest University long-term follow-up of type 2 myocardial infarction: The Wake-Up T2MI Registry, Hanumantha R. Jogu and Waqas Qureshi

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Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis, Shashi Kant, Siobhan M. Craige, Kai Chen, Michaella M. Reif, Heather Learnard, Mark Kelly, Amada D. Caliz, Khanh-Van T. Tran, Kasmir Ramo, Owen M. Peters, Marc R. Freeman, Roger J. Davis, and John F. Keaney Jr.

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Orbital Atherectomy for Calcific Coronary Artery Disease in Patients With Severe Aortic Stenosis: A Safety and Feasibility Study, Ibrahim Kassas, Ahmed Nagy, Alvaro Alonso, Mohammed W. Akhter, Craig Smith, Mohamed Ahmed, Abdul Moiz Hafiz, Jennifer Walker, and Nikolaos Kakouros

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Proteomics Profiling and Risk of New-Onset Atrial Fibrillation: Framingham Heart Study, Darae Ko, Mark D. Benson, Debby Ngo, Qiong Yang, Martin G. Larson, Thomas J. Wang, Ludovic Trinquart, David D. McManus, Steven A. Lubitz, Patrick T. Ellinor, Ramachandran S. Vasan, Robert E. Gerszten, Emelia J. Benjamin, and Honghuang Lin

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The role of platelets in mediating a response to human influenza infection, Milka Koupenova-Zamor, Heather A. Corkrey, Olga Vitseva, Giorgia Manni, Catherine J. Pang, Lauren Clancy, Chen Yao, Jeffrey J. Rade, Daniel Levy, Jennifer P. Wang, Robert W. Finberg, Evelyn A. Kurt-Jones, and Jane E. Freedman

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Pollen-derived RNAs Are Found in the Human Circulation, Milka Koupenova-Zamor, Eric O. Mick, Heather A. Corkrey, Anupama Singh, Selim E. Tanriverdi, Olga Vitseva, Daniel Levy, Allison M. Keeler, Marzieh Ezzaty Mirhashemi, Mai K. Elmallah, Mark Gerstein, Joel Rozowsky, Kahraman Tanriverdi, and Jane E. Freedman

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Detection of Bleeding Events in Electronic Health Record Notes Using Convolutional Neural Network Models Enhanced With Recurrent Neural Network Autoencoders: Deep Learning Approach, Rumeng Li, Baotian Hu, Feifan Liu, Weisong Liu, Francesca Cunningham, David D. McManus, and Hong Yu

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Gait Speed and Mood, Cognition, and Quality of Life in Older Adults With Atrial Fibrillation, Francesca Marino, Darleen M. Lessard, Jane S. Saczynski, David D. McManus, Luke G. Silverman-Lloyd, Christopher M. Benson, Michael J. Blaha, and Molly E. Waring

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Circulating microRNAs miR-331 and miR-195 differentiate local luminal a from metastatic breast cancer, Peter McAnena, Kahraman Tanriverdi, Catherine Curran, K. Gilligan, Jane E. Freedman, James A. L. Brown, and Michael J. Kerin

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Geriatric Conditions and Prescription of Vitamin K Antagonists vs. Direct Oral Anticoagulants Among Older Patients With Atrial Fibrillation: SAGE-AF, David D. McManus, Catarina I. Kiefe, Darleen M. Lessard, Francesca Marino, Robert J. Goldberg, Jerry H. Gurwitz, Weijia Wang, and Bruce A. Barton

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Design and Preliminary Findings From a New Electronic Cohort Embedded in the Framingham Heart Study, David D. McManus, Ludovic Trinquart, Emelia J. Benjamin, Emily S. Manders, Kelsey Fusco, Lindsey S. Jung, Nicole L. Spartano, Vik Kheterpal, Christopher Nowak, Mayank Sardana, and Joanne M. Murabito

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Histone Deacetylase 1 and 2 are Essential for Early Cardiac Development, Zachary J. Milstone

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Exercise Rescues Gene Pathways Involved in Vascular Expansion and Promotes Functional Angiogenesis in Subcutaneous White Adipose Tissue, So Yun Min, Heather Learnard, Shashi Kant, Olga Gaelikman, Raziel Rojas-Rodriguez, Tiffany DeSouza, Anand Desai, John F. Keaney Jr., Silvia Corvera, and Siobhan M. Craige

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Heart rate, mortality, and the relation with clinical and subclinical cardiovascular diseases: results from the Gutenberg Health Study, Thomas Munzel, Omar Hahad, Tommaso Gori, Sebastian Hollmann, Natalie Arnold, Jurgen H. Prochaska, Andreas Schulz, Manfred Beutel, Norbert Pfeiffer, Irene Schmidtmann, Karl J. Lackner, John F. Keaney Jr., and Philipp S. Wild

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Anticoagulant Prescribing for Non-Valvular Atrial Fibrillation in the Veterans Health Administration, Adam J. Rose, Robert J. Goldberg, David D. McManus, Alok Kapoor, Victoria Wang, Weisong Liu, and Hong Yu

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Geriatric Elements and Oral Anticoagulant Prescribing in Older Atrial Fibrillation Patients: SAGE-AF, Jane S. Saczynski, Saket Sanghai, Catarina I. Kiefe, Darleen M. Lessard, Francesca Marino, Robert J. Goldberg, Jerry H. Gurwitz, Weijia Wang, Bruce A. Barton, and David D. McManus

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Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study, Joel Salinas, Honghuang Lin, Hugo J. Aparico, Tianxiao Huan, Chunyu Liu, Jian Rong, Alexa Beiser, Jayandra J. Himali, Jane E. Freedman, Martin G. Larson, Jonathan Rosand, Hermona Soreq, Daniel Levy, and Sudha Seshadri

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Provider-Level Variation in Smoking Cessation Assistance Provided in the Cardiology Clinics: Insights From the NCDR PINNACLE Registry, Mayank Sardana, Yuanyuan Tang, Jared W. Magnani, Ira S. Ockene, Jeroan J. Allison, Suzanne V. Arnold, Phillip G. Jones, Thomas M. Maddox, Salim S. Virani, and David D. McManus

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Age-and-sex stratified prevalence of atrial fibrillation in rural Western India: Results of SMART-India, a population-based screening study, Apurv Soni, Sunil Karna, Nisha Fahey, Saket Sanghai, Harshil Patel, Shyamsundar Raithatha, Sunil Thanvi, Somashekhar Nimbalkar, Ben Freedman, Jeroan J. Allison, and David D. McManus

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Comparison of On-Site Versus Remote Mobile Device Support in the Framingham Heart Study Using the Health eHeart Study for Digital Follow-up: Randomized Pilot Study Set Within an Observational Study Design, Nicole L. Spartano, Honghuang Lin, Fangui Sun, Kathryn L. Lunetta, Ludovic Trinquart, Maureen Valentino, Emily S. Manders, Mark J. Pletcher, Gregory M. Marcus, David D. McManus, Emelia J. Benjamin, Caroline S. Fox, Jeffrey E. Olgin, and Joanne M. Murabito

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Micro-RNAs Are Related to Epicardial Adipose Tissue in Participants With Atrial Fibrillation: Data From the MiRhythm Study, Khanh-Van T. Tran, Jordan Majka, Saket Sanghai, Mayank Sardana, Darleen M. Lessard, Zachary J. Milstone, Kahraman Tanriverdi, Jane E. Freedman, Timothy P. Fitzgibbons, and David D. McManus

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Circulating extracellular RNAs, myocardial remodeling, and heart failure in patients with acute coronary syndrome, Khanh-Van T. Tran, Kahraman Tanriverdi, Gerard P. Aurigemma, Darleen M. Lessard, Mayank Sardana, Matthew Parker, Amir Y. Shaikh, Matthew Gottbrecht, Zachary Milstone, Selim E. Tanriverdi, Olga Vitseva, John F. Keaney Jr., Catarina I. Kiefe, David D. McManus, and Jane E. Freedman

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Is Left Ventricular Global Longitudinal Strain by Two-Dimensional Speckle Tracking Echocardiography in Sepsis Cardiomyopathy Ready for Prime Time Use in the ICU, Venu Madhav Velagapudi, Rahul Pidikiti, and Dennis A. Tighe

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Physical, cognitive, and psychosocial conditions in relation to anticoagulation satisfaction among elderly adults with atrial fibrillation: The SAGE-AF study, Weijia Wang, Jane Saczynski, Darleen M. Lessard, Tanya Mailhot, Bruce A. Barton, Molly E. Waring, Felix Sogade, Robert M. Hayward Jr., Robert Helm, and David D. McManus

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Characteristics Associated With Facebook Use and Interest in Digital Disease Support Among Older Adults With Atrial Fibrillation: Cross-Sectional Analysis of Baseline Data From the Systematic Assessment of Geriatric Elements in Atrial Fibrillation (SAGE-AF) Cohort, Molly E. Waring, Mellanie T. Hills, Darleen M. Lessard, Jane S. Saczynski, Brooke A. Libby, Marta M. Holovatska, Alok Kapoor, Catarina I. Kiefe, and David D. McManus

Publications from 2018

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Are we “missing the big picture” in transitions of care? Perspectives of healthcare providers managing patients with unplanned hospitalization, Hawa Ozien Abu, Milena D. Anatchkova, Nathaniel A. K. Erskine, Joanne Lewis, David D. McManus, Catarina I. Kiefe, and Heena P. Santry

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TIP55, a splice isoform of the KAT5 acetyltransferase, is essential for developmental gene regulation and organogenesis, Diwash Acharya, Bernadette Nera, Zachary J. Milstone, Lauren Bourke, Yeonsoo Yoon, Jaime A. Rivera-Pérez, Chinmay M. Trivedi, and Thomas G. Fazzio

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Dabigatran Versus Rivaroxaban for Secondary Stroke Prevention in Patients with Atrial Fibrillation Rehabilitated in Skilled Nursing Facilities, Matthew Alcusky, Anne L. Hume, Marc Fisher, Jennifer Tjia, Robert J. Goldberg, David D. McManus, and Kate L. Lapane

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Impact of training primary care physicians in behavioral counseling to reduce cardiovascular disease risk factors in Ecuador, Manuel E. Baldeon, Marco Fornasini, Nancy Flores, Philip A. Merriam, Milagros C. Rosal, Juan C. Zevallos, and Ira S. Ockene

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Motion and Noise Artifact-Resilient Atrial Fibrillation Detection using a Smartphone, Jo Woon Chong, Chae Ho Cho, Fatemehsadat Tabei, Duy Le-Anh, Nada Esa, David D. McManus, and Ki H. Chon

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Plasma Circulating Extracellular RNAs in Left Ventricular Remodeling Post-Myocardial Infarction, Kirsty M. Danielson, Kahraman Tanriverdi, Jane E. Freedman, and Saumya Das

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Barriers to Healthcare Access and to Improvements in Health-Related Quality of Life After an Acute Coronary Syndrome (From TRACE-CORE), Nathaniel A. K. Erskine, Barbara L. Gandek, Hoang V. Tran, Hawa Ozien Abu, David D. McManus, Catarina I. Kiefe, and Robert J. Goldberg

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Barriers to Healthcare Access and Long-Term Survival After an Acute Coronary Syndrome, Nathaniel A. K. Erskine, Molly E. Waring, David D. McManus, Darleen M. Lessard, Catarina I. Kiefe, and Robert J. Goldberg

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Antiplatelet Therapy Changes for Patients With Myocardial Infarction With Recurrent Ischemic Events: Insights Into Contemporary Practice From the TRANSLATE-ACS (Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) Study, Alexander C. Fanaroff, Lisa A. Kaltenbach, Eric D. Peterson, Mohammed W. Akhter, Mark B. Effron, Timothy D. Henry, and Tracy Y. Wang

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Antiplatelet Therapy Changes for Patients With Myocardial Infarction With Recurrent Ischemic Events: Insights Into Contemporary Practice From the TRANSLATE-ACS (Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) Study, Alexander C. Fanaroff, Lisa A. Kaltenbach, Eric D. Peterson, Mohammed W. Akhter, Mark B. Effron, Timothy D. Henry, and Tracy Y. Wang

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Device Therapies Among Patients Receiving Primary Prevention Implantable Cardioverter-Defibrillators in the Cardiovascular Research Network, Robert T. Greenlee, Jerry H. Gurwitz, and David D. McManus

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Sex-differences in post-discharge outcomes among patients hospitalized for atrial fibrillation, Bindu Kalesan, Amartya Kundu, Aditya Vaze, Elizabeth Pino, Allan J. Walkey, Ramachandran S. Vasan, and David D. McManus

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SUPPORT-AF: Piloting a Multi-Faceted, Electronic Medical Record-Based Intervention to Improve Prescription of Anticoagulation, Alok Kapoor, Azraa Amroze, Jessica G. Golden, Sybil L. Crawford, Kevin O'Day, Rasha Elhag, Ahmed Nagy, Steve A. Lubitz, Jane S. Saczynski, Jomol Mathew, and David D. McManus

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Relation of Orthostatic Hypotension With New-Onset Atrial Fibrillation (From the Framingham Heart Study), Darae Ko, Sarah R. Preis, Steven A. Lubitz, David D. McManus, Ramachandran S. Vasan, Naomi M. Hamburg, Emelia J. Benjamin, and Gary F. Mitchell

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Micro RNAs from DNA Viruses are Found Widely in Plasma in a Large Observational Human Population, Milka Koupenova-Zamor, Eric O. Mick, Heather A. Corkrey, Tianxiao Huan, Lauren Clancy, Ravi Shah, Emelia J. Benjamin, Daniel Levy, Evelyn A. Kurt-Jones, Kahraman Tanriverdi, and Jane E. Freedman

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Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity, Milka Koupenova-Zamor and Katya Ravid

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Recent Trends in Oral Anticoagulant Use and Post-Discharge Complications Among Atrial Fibrillation Patients with Acute Myocardial Infarction, Amartya Kundu, Kevin O. Day, Darleen M. Lessard, Joel M. Gore, Hong Yu, Mohammed W. Akhter, Daniel Z. Fisher, Robert M. Hayward Jr, Nils Henninger, Alok Kapoor, Jorge L. Yarzebski, Robert J. Goldberg, and David D. McManus

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Extraction of Information Related to Adverse Drug Events from Electronic Health Record Notes: Design of an End-to-End Model Based on Deep Learning, Fei Li, Weisong Liu, and Hong Yu

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Efficacy and safety of direct oral anticoagulants approved for cardiovascular indications: Systematic review and meta-analysis, Raghavendra Charan Makam, David C. Hoaglin, David D. McManus, Victoria Wang, Joel M. Gore, Frederick A. Spencer, Richeek Pradhan, Hoang Tran, Hong Yu, and Robert J. Goldberg

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Atrial fibrillation is associated with anterior predominant white matter lesions in patients presenting with embolic stroke, Yunis M. Mayasi, Johanna Helenius, David D. McManus, Richard P. Goddeau Jr, Adalia H. Jun-O'Connell, Majaz Moonis, and Nils Henninger

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Histone Deacetylase 3 (HDAC3) Regulates Lymphatic Vascular Development, Harish P. Palleti Janardhan

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Multi-ethnic genome-wide association study for atrial fibrillation, Carolina Roselli, Nada Esa, David D. McManus, Kahraman Tanriverdi, and Patrick T. Ellinor

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Indexed Left Atrial Adipose Tissue Area Is Associated With Severity of Atrial Fibrillation and Atrial Fibrillation Recurrence Among Patients Undergoing Catheter Ablation, Saket R. Sanghai, Mayank Sardana, Barinder Hansra, Darleen M. Lessard, Seth T. Dahlberg, Gerard P. Aurigemma, Timothy P. Fitzgibbons, and David D. McManus

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Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: The Framingham Offspring Study, Mayank Sardana, Darleen M. Lessard, Bruce A. Barton, Gary F. Mitchell, Aditya Vaze, and David D. McManus

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Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study, Laila Staerk, Biqi Wang, Sarah R. Preis, Martin G. Larson, Steven A. Lubitz, Patrick T. Ellinor, David D. McManus, Darae Ko, Lu-Chen Weng, Kathryn L. Lunetta, Lars Frost, Emelia J. Benjamin, and Ludovic Trinquart

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A Novel Personalized Motion and Noise Artifact (MNA) Detection Method for Smartphone Photoplethysmograph (PPG) Signals, Fatemehsadat Tabei, Rajnish Kumar, Tra Nguyen Phan, David D. McManus, and Jo Woon Chong