This collection showcases journal articles and other publications and presentations written by faculty and researchers of the Department of Medicine's Division of Cardiovascular Medicine.

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Publications from 2018

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Plasma Circulating Extracellular RNAs in Left Ventricular Remodeling Post-Myocardial Infarction, Kirsty M. Danielson, Kahraman Tanriverdi, Jane E. Freedman, and Saumya Das

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Barriers to Healthcare Access and Long-Term Survival After an Acute Coronary Syndrome, Nathaniel A. K. Erskine, Molly E. Waring, David D. McManus, Darleen M. Lessard, Catarina I. Kiefe, and Robert J. Goldberg

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Antiplatelet Therapy Changes for Patients With Myocardial Infarction With Recurrent Ischemic Events: Insights Into Contemporary Practice From the TRANSLATE-ACS (Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) Study, Alexander C. Fanaroff, Lisa A. Kaltenbach, Eric D. Peterson, Mohammed W. Akhter, Mark B. Effron, Timothy D. Henry, and Tracy Y. Wang

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Antiplatelet Therapy Changes for Patients With Myocardial Infarction With Recurrent Ischemic Events: Insights Into Contemporary Practice From the TRANSLATE-ACS (Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) Study, Alexander C. Fanaroff, Lisa A. Kaltenbach, Eric D. Peterson, Mohammed W. Akhter, Mark B. Effron, Timothy D. Henry, and Tracy Y. Wang

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Device Therapies Among Patients Receiving Primary Prevention Implantable Cardioverter-Defibrillators in the Cardiovascular Research Network, Robert T. Greenlee, Jerry H. Gurwitz, and David D. McManus

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Micro RNAs from DNA Viruses are Found Widely in Plasma in a Large Observational Human Population, Milka Koupenova-Zamor, Eric O. Mick, Heather A. Corkrey, Tianxiao Huan, Lauren Clancy, Ravi Shah, Emelia J. Benjamin, Daniel Levy, Evelyn A. Kurt-Jones, Kahraman Tanriverdi, and Jane E. Freedman

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Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity, Milka Koupenova-Zamor and Katya Ravid

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Recent Trends in Oral Anticoagulant Use and Post-Discharge Complications Among Atrial Fibrillation Patients with Acute Myocardial Infarction, Amartya Kundu, Kevin O. Day, Darleen M. Lessard, Joel M. Gore, Hong Yu, Mohammed W. Akhter, Daniel Z. Fisher, Robert M. Hayward Jr, Nils Henninger, Alok Kapoor, Jorge L. Yarzebski, Robert J. Goldberg, and David D. McManus

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Efficacy and safety of direct oral anticoagulants approved for cardiovascular indications: Systematic review and meta-analysis, Raghavendra Charan Makam, David C. Hoaglin, David D. McManus, Victoria Wang, Joel M. Gore, Frederick A. Spencer, Richeek Pradhan, Hoang Tran, Hong Yu, and Robert J. Goldberg

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Atrial fibrillation is associated with anterior predominant white matter lesions in patients presenting with embolic stroke, Yunis M. Mayasi, Johanna Helenius, David D. McManus, Richard P. Goddeau Jr, Adalia H. Jun-O'Connell, Majaz Moonis, and Nils Henninger

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Indexed Left Atrial Adipose Tissue Area Is Associated With Severity of Atrial Fibrillation and Atrial Fibrillation Recurrence Among Patients Undergoing Catheter Ablation, Saket R. Sanghai, Mayank Sardana, Barinder Hansra, Darleen M. Lessard, Seth T. Dahlberg, Gerard P. Aurigemma, Timothy P. Fitzgibbons, and David D. McManus

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Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: The Framingham Offspring Study, Mayank Sardana, Darleen M. Lessard, Bruce A. Barton, Gary F. Mitchell, Aditya Vaze, and David D. McManus

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Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study, Laila Staerk, Biqi Wang, Sarah R. Preis, Martin G. Larson, Steven A. Lubitz, Patrick T. Ellinor, David D. McManus, Darae Ko, Lu-Chen Weng, Kathryn L. Lunetta, Lars Frost, Emelia J. Benjamin, and Ludovic Trinquart

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Magnitude and impact of multiple chronic conditions with advancing age in older adults hospitalized with acute myocardial infarction, Mayra Tisminetzky, Hoa L. Nguyen, Jerry H. Gurwitz, David D. McManus, Joel M. Gore, Sonal Singh, Jorge L. Yarzebski, and Robert J. Goldberg

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Increase in white blood cell count is associated with the development of atrial fibrillation after an acute coronary syndrome, Hoang V. Tran, Nathaniel A. K. Erskine, Hoa L. Nguyen, David D. McManus, Hamza H. Awad, Catarina I. Kiefe, and Robert J. Goldberg

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RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome, Matija Zelic, Justine E. Roderick, Joanne A. O'Donnell, Jesse Lehman, Sung Eun Lim, Harish P. Janardhan, Chinmay M. Trivedi, Manolis Pasparakis, and Michelle A. Kelliher

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Assessing the Readability of Medical Documents: A Ranking Approach, Jiaping Zheng and Hong Yu

Publications from 2017

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Atrial fibrillation, cognition and dementia: A review, Summer Aldrugh, Mayank Sardana, Nils Henninger, Jane S. Saczynski, and David D. McManus

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Outcomes Among Older Patients Receiving Implantable Cardioverter-Defibrillators for Secondary Prevention: From the NCDR ICD Registry, Jarrod K. Betz, David F. Katz, Pamela N. Peterson, Ryan T. Borne, Sana M. Al-Khatib, Yongfei Wang, Carolina Malta Hansen, David D. McManus, Jehu S. Mathew, and Frederick A. Masoudi

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Burden of Psychosocial and Cognitive Impairment in Patients With Atrial Fibrillation, John A. Bostrom, Jane S. Saczynski, Alexandra M. Hajduk, Kevin Donahue, Lawrence S. Rosenthal, Clifford Browning, Cynthia Ennis, Kevin C. Floyd, Heather Richardson, Nada Esa, Jessica Ogarek, and David D. McManus

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Implications of an inpatient warfarin dosing nomogram on safety outcomes post-discharge, Nibal Chamoun, C. Gabriela Macias, Jennifer L. Donovan, Robert A. Klugman, Joel M. Gore, Pascale Salameh, and Maichi T. Tran

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The role of RNA uptake in platelet heterogeneity, Lauren Clancy, Lea M. Beaulieu, Kahraman Tanriverdi, and Jane E. Freedman

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Platelet Transcriptome Heterogeneity: A Role for RNA Uptake in Vascular Health and Disease, Lauren R. Clancy

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A Robust Motion Artifact Detection Algorithm for Accurate Detection of Heart Rates From Photoplethysmographic Signals Using Time-Frequency Spectral Features, Duy Dao, S M. Salehizadeh A, Yeonsik Noh, Jo Woon Chong, Chae Ho Cho, David D. McManus, Chad E. Darling, and Yitzhak Mendelson

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A Historical Perspective on Presentations of Hypertensive Acute Heart Failure, Chad E. Darling, Jiaoyuan Elisabeth Sun, Jordan Goldberg, Peter Pang, Christopher W. Baugh, Darleen M. Lessard, and David D. McManus

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Cardiometabolic disease in South Asians: A global health concern in an expanding population, A. Das, B. Ambale-Venkatesh, J. A. C. Lima, Jane E. Freedman, A. Spahillari, R. Das, S. Das, R. V. Shah, and V. L. Murthy

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Activation of Inflammatory and Pro-Thrombotic Pathways in Acute Stress Cardiomyopathy, Timothy P. Fitzgibbons, Yvonne J. K. Edwards, Peter Shaw, Aline Iskandar, Mohamed Ahmed, Josiah T. Bote, Tejen Shah, Sumita Sinha, Robert E. Gerszten, John F. Keaney Jr., Michael R. Zile, and Gerard P. Aurigemma

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Challenges and Opportunities in Linking Long Noncoding RNAs to Cardiovascular, Lung, and Blood Diseases, Jane E. Freedman; Joseph M. Miano; and National Heart, Lung, and Blood Institute Workshop Participants

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A paradigm shift for socioeconomic justice and health: from focusing on inequalities to aiming at sustainable equity, Juan E. Garay and David E. Chiriboga

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Accuracy, Reproducibility And Bias Of Next Generation Sequencing For Quantitative Small RNA Profiling: A Multiple Protocol Study Across Multiple Laboratories, Maria D. Giraldez, Kahraman Tanriverdi, Jane E. Freedman, and Muneesh Tewari

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Race and place differences in patients hospitalized with an acute coronary syndrome: Is there double jeopardy? Findings from TRACE-CORE, Robert J. Goldberg, Joel M. Gore, David D. McManus, Richard H. McManus, Mayra Tisminetzky, Darleen M. Lessard, Jerry H. Gurwitz, David C. Parish, Jeroan J. Allison, Connie Ng Hess, Tracy Wang, and Catarina I. Kiefe

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Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits, Tianxiao Huan, George Chen, Chunyu Liu, Anindya Bhattacharya, Jian Rong, Brian H. Chen, Sudha Seshadri, Kahraman Tanriverdi, Jane E. Freedman, Martin G. Larson, Joanne M. Murabito, and Daniel Levy

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Hdac3 regulates lymphovenous and lymphatic valve formation, Harish P. Janardhan, Zachary J. Milstone, Masahiro Shin, Nathan D. Lawson, John F. Keaney Jr., and Chinmay M. Trivedi

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Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies, Roby Joehanes, Kahraman Tanriverdi, Jane E. Freedman, and Peter J. Munson

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Differential Impact of Serial Measurement of Nonplatelet Thromboxane Generation on Long-Term Outcome After Cardiac Surgery, Nikolaos Kakouros, Tyler J. Gluckman, John V. Conte, Thomas S. Kickler, Katherine Laws, Bruce A. Barton, and Jeffrey J. Rade

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Pacemaker malfunction risks within the electromagnetically rich hospital environment, Nikolaos Kakouros and Stavros N. Kakouros

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A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress, Shashi Kant, Claire L. Standen, Caroline Morel, Dae Young Jung, Jason K. Kim, Wojciech Swat, Richard A. Flavell, and Roger J. Davis

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CHIP-ping Away at Atherosclerosis, John F. Keaney Jr.

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Thrombosis and platelets: an update, Milka Koupenova-Zamor, Beate E. Kehrel, Heather A. Corkrey, and Jane E. Freedman

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Peer Review Practices for Evaluating Biomedical Research Grants: A Scientific Statement From the American Heart Association, Lucy Liaw, Lance B. Becker, Nehal N. Mehta, and Laura Liscum

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Methylome-wide Association Study of Atrial Fibrillation in Framingham Heart Study, Honghuang Lin, Xiaoyan Yin, Zhijun Xie, Kathryn L. Lunetta, Steven A. Lubitz, Martin G. Larson, Darae Ko, Jared W. Magnani, Michael M. Mendelson, Chunyu Liu, David D. McManus, Daniel Levy, Patrick T. Ellinor, and Emelia J. Benjamin

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Short-Term Exposure to Ambient Air Pollution and Biomarkers of Systemic Inflammation: The Framingham Heart Study, Wenyuan Li, Kirsten S. Dorans, Elissa H. Wilker, Mary B. Rice, Petter L. Ljungman, Joel D. Schwartz, Brent A. Coull, Petros Koutrakis, Diane R. Gold, John F. Keaney Jr., Ramachandran S. Vasan, Emelia J. Benjamin, and Murray A. Mittleman

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Relations of Liver Fat With Prevalent and Incident Atrial Fibrillation in the Framingham Heart Study, Michelle T. Long, Xiaoyan Yin, Martin G. Larson, Patrick T. Ellinor, Steven A. Lubitz, David D. McManus, Jared W. Magnani, Laila Staerk, Darae Ko, Robert H. Helm, Udo Hoffmann, Raymond T. Chung, and Emelia J. Benjamin

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Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study, Steven A. Lubitz, Xiaoyan Yin, David D. McManus, Lu-Chen Weng, Hugo J. Aparicio, Allan J. Walkey, Jose Rafael Romero, Carlos S. Kase, Patrick T. Ellinor, Philip A. Wolf, Sudha Seshadri, and Emelia J. Benjamin

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Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors, David D. McManus, Jian Rong, Tianxiao Huan, Sean Lacey, Kahraman Tanriverdi, Peter J. Munson, Martin G. Larson, Roby Joehanes, Venkatesh Murthy, Ravi Shah, Jane E. Freedman, and Daniel Levy

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Stroke and Circulating Extracellular RNAs, Eric O. Mick, Ravi Shah, Kahraman Tanriverdi, Venkatesh Murthy, Mark Gerstein, Joel Rozowsky, Robert Kitchen, Martin G. Larson, Daniel Levy, and Jane E. Freedman

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Histone deacetylase 1 and 2 are essential for murine neural crest proliferation, pharyngeal arch development and craniofacial morphogenesis., Zachary J. Milstone, Grace Lawson, and Chinmay M. Trivedi

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Cross-sectional relations of whole-blood miRNA expression levels and hand grip strength in a community sample, Joanne M. Murabito, Jian Rong, Kathryn L. Lunetta, Tianxiao Huan, Honghuang Lin, Qiang Zhao, Jane E. Freedman, Kahraman Tanriverdi, Daniel Levy, and Martin G. Larson

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Role of Energy Metabolism in the Thermogenic Gene Program, Minwoo Nam

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Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression, Minwoo Nam, Thomas E. Akie, Masato Sanosaka, Siobhan M. Craige, Shashi Kant, John F. Keaney Jr., and Marcus P. Cooper

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Ten-Year (2001-2011) Trends in the Incidence Rates and Short-Term Outcomes of Early Versus Late Onset Cardiogenic Shock After Hospitalization for Acute Myocardial Infarction, Hoa L. Nguyen, Jorge L. Yarzebski, Darleen M. Lessard, Joel M. Gore, David D. McManus, and Robert J. Goldberg

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Serum brain-derived neurotrophic factor and risk of atrial fibrillation, Faisal Rahman, Jayandra J. Himali, Xiaoyan Yin, Alexa S. Beiser, Patrick T. Ellinor, Steven A. Lubitz, Ramachandran S. Vasan, Jared W. Magnani, David D. McManus, Sudha Seshadri, and Emelia J. Benjamin

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Change in Cognitive Function in the Month After Hospitalization for Acute Coronary Syndromes: Findings From TRACE-CORE (Transition, Risks, and Actions in Coronary Events-Center for Outcomes Research and Education), Jane S. Saczynski, David D. McManus, Molly E. Waring, Darleen M. Lessard, Milena D. Anatchkova, Jerry H. Gurwitz, Jeroan J. Allison, Arlene S. Ash, Richard H. McManus, David C. Parish, Robert J. Goldberg, and Catarina I. Kiefe

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Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia, Louis A. Saddic, Sarah M. Nicoloro, Olga T. Gupta, Michael P. Czech, Joshua Gorham, Stanton K. Shernan, Christine E. Seidman, Jon G. Seidman, Sary F. Aranki, Simon C. Body, Timothy P. Fitzgibbons, and Jochen D. Muehlschlegel

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Beta-Blocker Use Is Associated With Impaired Left Atrial Function in Hypertension, Mayank Sardana, Amer Ahmed Syed, Zeba Hashmath, Timothy S. Phan, Maheswara R. Koppula, Uzma Kewan, Zoubair Ahmed, Ravikantha Chandamuri, Swapna Varakantam, Ejaz Shah, Ryan Gorz, Scott R. Akers, and Julio A. Chirinos

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Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes, Ravi Shah, Venkatesh Murthy, Kahraman Tanriverdi, Eric O. Mick, and Jane E. Freedman

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Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes, Ravi Shah, Venkatesh Murthy, Kahraman Tanriverdi, Eric O. Mick, and Jane E. Freedman

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Subclinical Atherosclerosis, Statin Eligibility, and Outcomes in African American Individuals: The Jackson Heart Study, Ravi V. Shah, Aferdita Spahillari, Stanford Mwasongwe, J. J. Carr, James G. Terry, Robert J. Mentz, Daniel Addison, Udo Hoffmann, Jared Reis, Jane E. Freedman, Joao A. C. Lima, Adolfo Correa, and Venkatesh L. Murthy

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Association of Multiorgan Computed Tomographic Phenomap With Adverse Cardiovascular Health Outcomes: The Framingham Heart Study, Ravi V. Shah, Ashish S. Yeri, Venkatesh L. Murthy, Joe M. Massaro, Ralph Sr. D'Agostino, Jane E. Freedman, Michelle T. Long, Caroline S. Fox, Saumya Das, Emelia J. Benjamin, Ramachandran S. Vasan, Christopher J. O'Donnell, and Udo Hoffmann

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Small RNA-seq during acute maximal exercise reveal RNAs involved in vascular inflammation and cardiometabolic health: brief report, Ravi Shah, Luke Wooster, Cole Shields. Bailey, Kahraman Tanriverdi, Lea M. Beaulieu, Jane E. Freedman, and Saumya Das

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Decreased Thromboembolic Stroke but not Atherosclerosis or Vascular Remodeling in Mice with ROCK2-deficient Platelets, Nikola Sladojevic, Goo Taeg. Oh, Hyung-Hwan Kim, Lea M. Beaulieu, Herve Falet, Karol Kaminski, Jane E. Freedman, and James K. Liao

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RAHI-SATHI Indo-U.S. Collaboration: The Evolution of a Trainee-Led Twinning Model in Global Health Into a Multidisciplinary Collaborative Program, Apurv Soni, Nisha Fahey, Abraham Jaffe, Tiffany A. Moore Simas, Nancy Byatt, Michael Chin, David D. McManus, Michaela Tracey, Jasmine A. Khubchandani, Haley Newman, Allison Earon, Hannah Rosenfield, Anna Handorf, Brittany Novak, John Bostrom, Anindita Deb, Milagros C. Rosal, Patricia A. McQuilkin, Heena Santry, Melissa A. Fischer, and Jeroan J. Allison

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Study protocol for Smartphone Monitoring for Atrial fibrillation in Real-Time in India (SMART-India): a community-based screening and referral programme, Apurv Soni, Nisha Fahey, Shyamsundar Raithatha, Anna Handorf, John Bostrom, Ravi Shah, Robert J. Goldberg, Jeroan J. Allison, and David D. McManus

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Ideal Cardiovascular Health, Cardiovascular Remodeling, and Heart Failure in Blacks: The Jackson Heart Study, Aferdita Spahillari, Jane E. Freedman, and Ravi V. Shah

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Association Between Leukocyte Telomere Length and the Risk of Incident Atrial Fibrillation: The Framingham Heart Study, Laila Staerk, Biqi Wang, Kathryn L. Lunetta, Robert H. Helm, Darae Ko, Jason A. Sherer, Patrick T. Ellinor, Steven A. Lubitz, David D. McManus, Ramachandran S. Vasan, Emelia J. Benjamin, and Ludovic Trinquart

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Magnitude and Characteristics of Patients Who Survived an Acute Myocardial Infarction, Mayra Tisminetzky, Tracy Y. Wang, Jerry H. Gurwitz, Lisa A. Kaltenbach, David D. McManus, Joel M. Gore, Eric Peterson, and Robert J. Goldberg

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Underuse of Effective Cardiac Medications Among Women, Middle-Aged Adults, and Racial/Ethnic Minorities With Coronary Artery Disease (from the National Health and Nutrition Examination Survey 2005 to 2014), Hoang Tran, Molly E. Waring, David D. McManus, Nathaniel Erskine, Van T. H. Do, Catarina I. Kiefe, and Robert J. Goldberg

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When Rhythm Changes Cause the Blues: New-Onset Atrial Fibrillation during Sepsis, Allan J. Walkey and David D. McManus

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MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage, Christine M. Willinger, Kahraman Tanriverdi, Jane E. Freedman, Martin G. Larson, and Daniel Levy

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Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits, Chen Yao, Roby Joehanes, Andrew D. Johnson, Tianxiao Huan, Chunyu Liu, Jane E. Freedman, Peter J. Munson, David A. Hill, Marc Vidal, and Daniel Levy

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Association of Parental Obesity and Diabetes Mellitus With Circulating Adipokines in Nonobese Nondiabetic Offspring, Justin P. Zachariah, Rene Quiroz, Danielle Enserro, Charlotte Andersson, John F. Keaney Jr., Lisa M. Sullivan, and Ramachandran S. Vasan

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Prospective Relation of Circulating Adipokines to Incident Metabolic Syndrome: The Framingham Heart Study, Justin P. Zachariah, Rene Quiroz, Kerrie P. Nelson, Zhaoyang Teng, John F. Keaney Jr., Lisa M. Sullivan, and Ramachandran S. Vasan

Publications from 2016

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Temporal trends in all-cause mortality according to smoking status: Insights from the Global Registry of Acute Coronary Events, Yaron Arbel, Gordon FitzGerald, Andrew T. Yan, Mary K. Tan, Keith A. A. Fox, Joel M. Gore, Phillippe Gabriel Steg, Kim A. Eagle, David Brieger, Gilles Montalescot, Andrzej Budaj, Jose Lopez-Sendon, Alvaro Avezum, Christopher B. Granger, and Shaun G. Goodman

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Magnitude, treatment, and impact of diabetes mellitus in patients hospitalized with non-ST segment elevation myocardial infarction: A community-based study, Hamza H. Awad, Mayra Tisminetzky, Diana Metry, David D. McManus, Jorge L. Yarzebski, Joel Gore, and Robert J. Goldberg

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Hepatic steatosis is associated with cardiometabolic risk in a rural Indian population: A prospective cohort study, Anamitra Barik, Jane E. Freedman, and Abhijit Chowdhury

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Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys, Dan H. Barouch, Hyung-joo Kang, and Wenjun Li

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Platelet functional and transcriptional changes induced by intralipid infusion, Lea M. Beaulieu, Olga Vitseva, Kahraman Tanriverdi, Alper Kucukural, Eric O. Mick, Naomi Hamburg, Joseph Vita, and Jane E. Freedman

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Decade-long trends in the timeliness of receipt of a primary percutaneous coronary intervention, Han-Yang Chen, Joel M. Gore, Kate L. Lapane, Jorge L. Yarzebski, Sharina D. Person, Catarina I. Kiefe, and Robert J. Goldberg

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Decade-Long Trends in the Frequency of 90-Day Rehospitalizations After Hospital Discharge for Acute Myocardial Infarction, Han-Yang Chen, Mayra Tisminetzky, Jorge D. Yarzebski, Joel M. Gore, and Robert J. Goldberg

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Fitness in Young Adults as an Independent Predictor of Risk for Cardiovascular Disease, David E. Chiriboga and Ira S. Ockene

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A comparison of the CHARGE-AF and the CHA2DS2-VASc risk scores for prediction of atrial fibrillation in the Framingham Heart Study, Ingrid E. Christophersen, Xiaoyan Yin, Martin G. Larson, Steven A. Lubitz, Jared W. Magnani, David D. McManus, Patrick T. Ellinor, and Emelia J. Benjamin

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Blood-Derived Extracellular RNA and Platelet Pathobiology: Adding Pieces to a Complex Circulating Puzzle, Lauren Clancy and Jane E. Freedman

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PGC-1alpha dictates endothelial function through regulation of eNOS expression, Siobhan M. Craige, Swenja Kroller-Schon, Chunying Li, Shashi Kant, Shenghe Cai, Kai Chen, Mayur M. Contractor, Yongmei Pei, Eberhard Schulz, and John F. Keaney Jr.

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IL-10 prevents aging-associated inflammation and insulin resistance in skeletal muscle, Sezin Dagdeviren, Dae Young Jung, Randall H. Friedline, Hye Lim Noh, Jong Hun Kim, Payal R. Patel, Nicholas Tsitsilianos, Kunikazu Inashima, Duy A. Tran, Xiaodi Hu, Marilia M. Loubato, Siobhan M. Craige, Jung Yeon Kwon, Ki Won. Lee, and Jason K. Kim

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Biological Therapies for Atrial Fibrillation: Ready for Prime Time, J. Kevin Donahue

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Characterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction, John D. Eicher, Yoshiyuki Wakabayashi, Olga Vitseva, Nada Esa, Yanqin Yang, Jun Zhu, Jane Freedman, David D. McManus, and Andrew D. Johnson

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Emerging evidence for beneficial macrophage functions in atherosclerosis and obesity-induced insulin resistance, Timothy P. Fitzgibbons and Michael P. Czech

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Diverse human extracellular RNAs are widely detected in human plasma, Jane E. Freedman, Eric Mick, Lea M. Beaulieu, Selim E. Tanriverdi, Milka Koupenova-Zamor, Ekaterina Mikhalev, and Kahraman Tanriverdi

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Decade-Long Trends (2001-2011) in the Incidence and Hospital Death Rates Associated with the In-Hospital Development of Cardiogenic Shock after Acute Myocardial Infarction, Robert J. Goldberg, Raghavendra Charan P. Makam, Jorge L. Yarzebski, David D. McManus, Darleen M. Lessard, and Joel M. Gore

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Spontaneous coronary artery dissection in a patient with autosomal dominant polycystic kidney disease: a case report, Peeyush Grover and Timothy P. Fitzgibbons

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Practical Care Support During the Early Recovery Period After Acute Coronary Syndrome, Alexandra M. Hajduk, Jacquelyn E. Hyde, Molly E. Waring, Darleen M. Lessard, David D. McManus, Elizabeth B. Fauth, Stephenie C. Lemon, and Jane S. Saczynski

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Perspective: Randomized Controlled Trials Are Not a Panacea for Diet-Related Research, James R. Hebert, Edward A. Frongillo, Swann A. Adams, Gabrielle M. Turner-McGrievy, Thomas G. Hurley, Donald R. Miller, and Ira S. Ockene

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Atrial Fibrillation Is Associated With a Worse 90-Day Outcome Than Other Cardioembolic Stroke Subtypes, Nils Henninger, Richard P. Goddeau, Ameeta Karmarkar, Johanna Helenius, and David D. McManus

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Performance of the GRACE Risk Score 2.0 Simplified Algorithm for Predicting 1-Year Death After Hospitalization for an Acute Coronary Syndrome in a Contemporary Multiracial Cohort, Wei Huang, Gordon FitzGerald, Robert J. Goldberg, Joel M. Gore, Richard H. McManus, Hamza H. Awad, Molly E. Waring, Jeroan J. Allison, Jane S. Saczynski, Catarina I. Kiefe, Keith A. A. Fox, Frederick A. Anderson Jr., David D. McManus, and TRACE-CORE Investigators

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Risk Factors for Nonplatelet Thromboxane Generation After Coronary Artery Bypass Graft Surgery, Nikolaos Kakouros, Saman Nazarian, Patrizia B. Stadler, Thomas Kickler, and Jeffrey J. Rade

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Postmenopausal Hormone Therapy and Atherosclerosis--Time Is of the Essence, John F. Keaney Jr. and Caren G. Solomon

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Atrial fibrillation without comorbidities: Prevalence, incidence and prognosis (from the Framingham Heart Study), Eun-Jeong Kim, Xiaoyan Yin, Joao D. Fontes, Jared W. Magnani, Steven A. Lubitz, David D. McManus, Sudha Seshadri, Ramachandran S. Vasan, Patrick T. Ellinor, Martin G. Larson, Emelia J. Benjamin, and Michael Rienstra

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Metabolomic Profiling in Relation to New-Onset Atrial Fibrillation (from the Framingham Heart Study), Darae Ko, David D. McManus, and Michael Rienstra

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Metabolomic Profiling in Relation to New-Onset Atrial Fibrillation (from the Framingham Heart Study), Darae Ko, David D. McManus, and Michiel Rienstra

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Relation of Atrial Fibrillation in Acute Myocardial Infarction to In-Hospital Complications and Early Hospital Readmission, Amartya Kundu, Kevin O'Day, Amir Y. Shaikh, Darleen M. Lessard, Jane S. Saczynski, Jorge L. Yarzebski, Chad E. Darling, Ramses Thabet, Mohammed W. Akhter, Kevin C. Floyd, Robert J. Goldberg, and David D. McManus