Laminin binding proteins
Department of Cancer Biology
Animals; Cytosol; Integrins; Laminin; Lectins; Neoplasm Proteins; Receptors, Immunologic; Receptors, Laminin; Signal Transduction
Cancer Biology | Neoplasms
Cells express many proteins that bind to laminin, the major adhesive component of basement membranes. Some of these, specifically integrins, function as transmembrane receptors that 'signal' the presence of laminin on the cell surface to the cytoplasm. Lectins constitute a second class of laminin binding proteins that may augment integrin function by interacting with laminin carbohydrate. Caution must be used in ascribing functions to other laminin binding proteins, especially cytosolic proteins.
DOI of Published Version
Bioessays. 1991 Sep;13(9):469-73. Link to article on publisher's site
BioEssays : news and reviews in molecular, cellular and developmental biology
Mercurio, Arthur M. and Shaw, Leslie M., "Laminin binding proteins" (1991). Cancer Biology Publications and Presentations. 121.