Title

Single-molecule tracking in eukaryotic cell nuclei

UMMS Affiliation

Department of Biochemistry and Molecular Pharmacology; RNA Therapeutics Institute

Publication Date

2007-1

Document Type

Article

Subjects

Carbocyanines; Cell Nucleus; Green Fluorescent Proteins; HeLa Cells; Humans; Microscopy, Fluorescence; Nuclear Proteins; RNA-Binding Proteins; Recombinant Fusion Proteins; Ribonucleoprotein, U1 Small Nuclear; Transfection

Disciplines

Analytical Chemistry | Biochemistry | Biochemistry, Biophysics, and Structural Biology | Molecular Biology

Abstract

Visualization of single fluorescent molecules (single-molecule tracking, SMT) within cells provides a real-time molecular view of physiological processes in vivo.

DOI of Published Version

10.1007/s00216-006-0763-0

Source

Siebrasse JP, Grünwald D, Kubitscheck U. Single-molecule tracking in eukaryotic cell nuclei. Anal Bioanal Chem. 2007 Jan;387(1):41-4. doi:10.1007/s00216-006-0763-0.

Journal/Book/Conference Title

Analytical and bioanalytical chemistry

Comments

At the time of publication, David Grünwald was not yet affiliated with the University of Massachusetts Medical School.

Related Resources

Link to Article in PubMed

PubMed ID

17033772

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