Title

Small RNA-Directed Silencing: The Fly Finds Its Inner Fission Yeast

UMMS Affiliation

Department of Biochemistry and Molecular Pharmacology

Publication Date

2013-04-22

Document Type

Article

Subjects

RNA, Small Interfering

Disciplines

Biochemistry, Biophysics, and Structural Biology | Genetics and Genomics | Molecular Genetics

Abstract

Several recent studies demonstrate that piRNAs guide Piwi protein to repress transposon transcription in fly ovaries, much as fission yeast use siRNAs to silence repeat sequences. Still mysterious though is how Piwi targets euchromatic transposons for silencing, but not the specialized heterochromatic loci that produce piRNA precursors.

DOI of Published Version

10.1016/j.cub.2013.03.033

Source

Curr Biol. 2013 Apr 22;23(8):R318-20. doi: 10.1016/j.cub.2013.03.033. Link to article on publisher's site

Journal/Book/Conference Title

Current biology : CB

Related Resources

Link to Article in PubMed

PubMed ID

23618667

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