Simultaneous correction of the influence of skin color and fat on tissue spectroscopy by use of a two-distance fiber-optic probe and orthogonalization technique
Department of Anesthesiology
Adipose Tissue; *Algorithms; Artifacts; Equipment Design; Equipment Failure Analysis; Fiber Optic Technology; Humans; Muscle, Skeletal; Optical Fibers; Phantoms, Imaging; Pilot Projects; Skin Pigmentation; Spectroscopy, Fourier Transform Infrared; Transducers
Anesthesiology | Optics
We have demonstrated simultaneous correction for the optical interference of skin and fat in tissue spectra by using a two-distance fiber-optic probe. We obtained the correction by orthogonalizing the spectra collected at a long source-detector distance (SD) to the spectra collected at a short SD and mapped to the long SD space. The method was validated in tissuelike three-layer phantoms as well as preliminarily in human tissue. After the correction, a partial-least-squares model of the phantoms showed enhanced prediction performance.
DOI of Published Version
Opt Lett. 2005 Sep 1;30(17):2269-71. DOI 10.1364/OL.30.002269
Yang, Ye; Landry, Michelle R.; Soyemi, Olusola O.; Shear, Michael A.; Anunciacion, Dulce; and Soller, Babs R., "Simultaneous correction of the influence of skin color and fat on tissue spectroscopy by use of a two-distance fiber-optic probe and orthogonalization technique" (2005). Anesthesiology and Perioperative Medicine Publications. 97.