Title

Cytoskeleton--plasma membrane interactions

UMMS Affiliation

Department of Cell Biology

Date

11-6-1992

Document Type

Article

Subjects

Cell Adhesion; Cell Membrane; Cell Movement; Cell Physiology; Cells; Cytoskeleton; Homeostasis; Humans

Disciplines

Cell Biology | Life Sciences | Medicine and Health Sciences

Abstract

Proteins at the boundary between the cytoskeleton and the plasma membrane control cell shape, delimit specialized membrane domains, and stabilize attachments to other cells and to the substrate. These proteins also regulate cell locomotion and cytoplasmic responses to growth factors and other external stimuli. This diversity of cellular functions is matched by the large number of biochemical mechanisms that mediate the connections between membrane proteins and the underlying cytoskeleton, the so-called membrane skeleton. General organizational themes are beginning to emerge from examination of this biochemical diversity.

Rights and Permissions

Citation: Science. 1992 Nov 6;258(5084):955-64.

Related Resources

Link to article in PubMed

PubMed ID

1439807