Let a hundred flowers bloom: the role of context dependence in creating phenotypic diversity following targeted therapy
Program in Systems Biology
Cancer Biology | Cell Biology | Computational Biology | Molecular Biology | Systems Biology
Using a newly developed computational platform, COSPER, Litvin et al. (2015) identify context-dependent interactions between MEK and interferon signaling that underlie sensitivity and resistance to MEK inhibition in melanoma.
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Citation: Mol Cell. 2015 Mar 5;57(5):763-4. doi: 10.1016/j.molcel.2015.02.030. Link to article on publisher's site
Lee, Michael J., "Let a hundred flowers bloom: the role of context dependence in creating phenotypic diversity following targeted therapy" (2015). Program in Systems Biology Publications and Presentations. 61.